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1.
Biomark Med ; 17(4): 219-230, 2023 02.
Artigo em Inglês | MEDLINE | ID: mdl-37129507

RESUMO

Aim: This work was designed to investigate the relationship between cardiac outcomes and Naples Prognostic Score (NPS) among heart failure (HF) patients. Materials & methods: This retrospective observational study enrolled 298 consecutive individuals hospitalized for New York Heart Association class 3-4 HF. The primary outcome was all-cause mortality. Secondary outcomes were rehospitalization and in-hospital death. Results: The high NPS group had a statistically greater rate of all-cause mortality (p < 0.001). In Cox regression analysis, integrating NPS considerably improved the performance of the full model over the baseline model (adjusted hazard ratio = 2.28; p = 0.004). Based on time-dependent receiver operating characteristic curve analysis, the NPS model outperformed the baseline and CONUT score models in discriminatory power in predicting the probability of survival. Conclusion: NPS was associated with short- and midterm mortality as well as rehospitalization.


Heart failure is a serious condition that affects millions of individuals around the world. This study was designed to investigate whether there is a relationship between Naples Prognostic Score (NPS) and worse outcomes in heart failure patients. A total of 298 patients with advanced heart failure were included in the study. Patients with a high NPS are more likely to pass away and need to be readmitted to the hospital. NPS also predicted survival more accurately than some other variables at an average of 15 months follow-up. In conclusion, NPS was found to be useful in predicting short- and medium-term mortality and readmissions in patients with advanced heart failure.


Assuntos
Insuficiência Cardíaca , Humanos , Prognóstico , Mortalidade Hospitalar , Readmissão do Paciente , Estudos Retrospectivos
2.
J Arrhythm ; 37(3): 550-555, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34141006

RESUMO

BACKGROUND: The purpose of this meta-analysis was to evaluate the impact of image integration technique on clinical and procedural outcomes in patients undergoing radiofrequency catheter ablation of atrial fibrillation with a three-dimensional electroanatomic mapping system. METHODS: Randomized controlled trials were identified through a systematic literature search of PubMed and CENTRAL databases from inception to April 2020. The primary outcome was arrhythmia recurrence during the follow-up period. The secondary outcomes were the difference in total procedural time and fluoroscopy time. RESULTS: Four studies with a total of 749 patients were included. The pooled result showed no statistically significant difference between the groups with respect to arrhythmia recurrence (RR, 0.75; 95% CI, 0.47-1.21), fluoroscopy time (MD, -6 minutes; 95% CI, -23.4 to 11.3), and total procedural time (MD, 1.1 minutes; 95% CI, -31.8 to 34.1). CONCLUSION: Image integration to guide radiofrequency catheter ablation for patients with atrial fibrillation does not improve clinical and procedural outcomes.

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