Simultaneous Implant and Guided Bone Regeneration Using Bovine-Derived Xenograft and Acellular Dermal Matrix in Aesthetic Zone.

INTRODUCTION: Implant placement in the maxillary anterior area requires sufficient quantity and quality of both soft and hard tissue. In cases where soft and hard tissues are insufficient, additional regeneration using biomaterials is recommended. Treatment using bovine-derived xenograft and acellular dermal matrix (ADM) may increase bone volume and soft tissue thickness. Case and management: A 65-year-old woman sought help for discomfort and aesthetic issues with her denture, reporting missing teeth (11, 12, 13, 14, and 21) and bone volume shrinkage due to disuse atrophy. Intraoral examination revealed 1 mm gingival thickness. CBCT showed labio-palatal bone thickness of 6.0 mm, 5.8 mm, and 4.7 mm for teeth 21, 12 and 14, respectively. Implant planning and surgical guide fabrication were carried out before the surgery. Surgery included the placement of implants 3.3 mm in diameter and 12 mm in length, with the use of xenograft and ADM. Three months post-op, improvements in soft and hard tissues were observed, with a final prosthesis being a long-span implant-supported bridge. CONCLUSIONS: Disuse alveolar atrophy causes soft and hard tissue deficiency. The use of xenograft and ADM show favourable results even on a geriatric patient.

Evaluation of physiological responses to mental workload in n-back and arithmetic tasks.

Working memory tasks, such as n-back and arithmetic tasks, are frequently used in studying mental workload. The present study investigated and compared the sensitivity of several physiological measures at three levels of difficulty of n-back and arithmetic tasks. The results showed significant differences in fixation duration and pupil diameter among three task difficulty levels for both n-back and arithmetic tasks. Pupil diameters increase with increasing mental workload, whereas fixation duration decreases. Blink duration and heart rate (HR) were significantly increased as task difficulty increased in the n-back task, while root mean square of successive differences (RMSSD) and standard deviation of R-R intervals (SDNN) were significantly decreased in the arithmetic task. On the other hand, blink rate and Galvanic Skin Response (GSR) were not sensitive enough to assess the differences in task difficulty for both tasks. All significant physiological measures yielded significant differences between low and high task difficulty except for SDNN.Practitioner summary: This study aimed to assess the sensitivity levels of several physiological measures of mental workload in n-back and arithmetic tasks. It showed that pupil diameter was the most sensitive in both tasks. This study also found that most physiological indices are sensitive to an extreme change in task difficulty levels.

Accident patterns and prevention measures for occupational injuries in the Philippine food and beverage manufacturing industry.

BACKGROUND: The manufacturing industry is one of the catalysts for the Philippines. However, this sector is one of the most dangerous industries in the Philippines considering the frequency of occupational injuries. OBJECTIVE: To determine the primary and root causes of recorded accidents, demographics of the person involved, and solutions to prevent the recurrence of certain accidents. METHODS: This study analyzed 185 occupational injury cases in a food and beverage manufacturing company in the Philippines from January to December 2018. A comprehensive classification system was established to examine and code each case in terms of age, gender, working shift, employee type, tenure, department, category, activity during the accident, root cause of injury, injury classification, direct cause of injury, type of injury, part of body injured, agent of injury, and location of the accident. Cramer's V analysis and Phi coefficient analyses were employed on the subject cases to determine the significant factors and the corresponding extent of significance. RESULTS: The results showed that the majority of the occupational injuries were caused by stepping on, striking against, or stuck by objects (77 cases, 41.6%), caught in between (34 cases, 18.4%), fall (34 cases, 18.4%), and exposure or contact with extreme temperatures (24 cases, 13%). Interestingly, female workers who had accidents were more likely due to inadequate hazard information or lack of procedures whereas male workers were more likely due to failure to secure. The prevention measures such as passive safeguards and personal protective equipment, pictograms, and regular safety audits were derived from the results of these analyses. CONCLUSIONS: This study is the first comprehensive analysis of occupational injuries in the food and beverage industry in the Philippines. The findings can be applied to positively influence the effectiveness of prevention and rehabilitation programs mitigating workplace injuries and illnesses.

Effects of human performance improvement and operational learning on organizational safety culture and occupational safety and health management performance.

Human performance improvement (HPI) is a strategic approach for reducing and controlling human errors, while operational learning (OL) is part of the organization's knowledge management system focusing on day-to-day operations. This study explores the influence of HPI and OL on the development of organizational safety culture, occupational safety and health (OSH) management performance in one of Indonesia's largest oil producers. First, we conducted a focus group discussion with top management and then surveyed 260 workers. The data were then analysed using partial least squares structural equation modelling, finding that HPI has a positive significant influence on OL. Furthermore, HPI and OL have positive significant influences on OSH management performance, such that OL mediates the effects of HPI on organizational safety culture, OSH management performance. These findings imply the need to prioritize and implement measures to improve organizational safety culture, OSH management performance.

The Evaluation of Preference and Perceived Quality of Health Communication Icons Associated with COVID-19 Prevention Measures.

Icons have been widely utilized to describe and promote COVID-19 prevention measures. The purpose of this study was to analyze the preference and subjective design features of 133 existing icons associated with COVID-19 prevention measures published by the health and medical organizations of different countries. The 133 icons represent nineteen different function names, such as "Wash Hands" and "Wear Face Mask". A total of 57 participants were recruited to perform two different tests: ranking test and subjective rating test. The ranking test was conducted to elicit the preference ranking of seven icon designs representing each function name. It was followed by a subjective rating test using 13 semantic scales on the two most preferred icons to analyze their perceived quality. Spearmen correlation was applied to derive the possible correlations between users' rankings and the semantic scales, and Friedman's test was also performed to determine the true difference between ranking in terms of each semantic scale to provide a fully meaningful interpretation of the data. Generally, findings from the current study showed that the image presented in the icon is the key point that affects the icons' perceived quality. Interestingly, Spearman's correlation analysis between preference ranking and semantic scales showed that vague-clear, weak-strong, incompatible-compatible, and ineffective-effective were the four strongest semantic scales that highly correlated with the preference ranking. Considering the significant relationships between the semantic distances and the functions, images depicted in an icon should be realistic and as close as possible to its respected function to cater to users' preferences. In addition, the results of Spearman's correlation and Friedman's test also inferred that compatibility and clarity of icon elements are the main factors determining a particular icon's preferability. This study is the first comprehensive study to evaluate the icons associated with the COVID-19 prevention measures. The findings of this study can be utilized as the basis for redesigning icons, particularly for icons related to COVID-19 prevention measures. Furthermore, the approach can also be applied and extended for evaluating other medical icons.

Evaluation of Masticatory Performance and Patient Satisfaction Before and After Posterior Implant Restoration

ABSTRACT Objective: To evaluate the improvement in masticatory performances two weeks after posterior implant restoration. Material and Methods: Nine patients with missing first and second molars were included in the study. Masticatory performances were evaluated using subjective and objective methods utilizing color-changeable chewing gum and the visual analog scale (VAS) assessment. The subjects were asked to chew the color-changeable chewing gums before and two weeks after the posterior implant restoration. Their expectations regarding aesthetics and function were verified on the VAS before implant placement. Additionally, the VAS was used for the posttreatment completion rating two weeks after the implant restoration. Results: Significant differences in masticatory performance were noted at baseline (before implant posterior restoration) and two weeks after implant restoration (p<0.05). The posttreatment aesthetic and functional expectations ratings significantly exceeded the expectations (p<0.05). Conclusion: Masticatory performances were improved two weeks after implant restoration. In addition, the significant posttreatment ratings of the patients exceeded their initial expectations. In particular, patients with poor masticatory functions demonstrated significant improvements and satisfaction following implant restoration compared to those with good mastication. These findings indicate that a posterior implant restoration can increase the masticatory performance.

GIS-based approaches on the accessibility of referral hospital using network analysis and the spatial distribution model of the spreading case of COVID-19 in Jakarta, Indonesia.

BACKGROUND: The outbreak of the novel coronavirus (COVID-19) has rapidly spread, causing million confirmed cases, thousands of deaths, and economic losses. The number of cases of COVID-19 in Jakarta is the largest in Indonesia. Furthermore, Jakarta is the capital city of Indonesia which has the densest population in the country. There is need for geospatial analysis to evaluate the demand in contrast to the capacity of Referral Hospitals and to model the spreading case of Covid-19 in order to support and organize an effective health service. METHODS: We used the data from local government publicity for COVID-19 as trusted available sources. By using the verifiable data by observation from the local government, we estimated the spatial pattern of distribution of cases to estimate the growing cases. We performed service area and Origin-Destination (OD) Cost Matrix in support to existing referral hospital, and to create Standard Deviational Ellipse (SDE) model to determine the spatial distribution of COVID-19. RESULTS: We identified more than 12.4 million people (86.7%) based on distance-based service area, live in the well served area of the referral hospital. A total 2637 positive-infected cases were identified and highly concentrated in West Jakarta (1096 cases). The results of OD cost matrix in a range of 10 km show a total 908 unassigned cases from 24 patient's centroid which was highly concentrated in West Jakarta. CONCLUSIONS: Our results indicate the needs for additional referral hospitals specializing in the treatment of COVID-19 and spatial illustration map of the growth of COVID-19' case in support to the implementation of social distancing in Jakarta.

Preference ranking test for different icon design formats for smart living room and bathroom functions.

The current study illustrates the icon design process for 20 functions for a smart living room and smart bathroom of a commercial smart building control system. For each function name, seven icon formats (image-related, concept-related, semi-abstract, arbitrary, word, abbreviation, and combined) were developed by 30 graduate students and compared with a preference ranking test by another 13 executive MBA students. The results indicated that the combined, image-related, concept-related, semi-abstract, word, and abbreviation each had nine, four, three, two, one and one function names ranked as the most preferred format, respectively. Since all the design formats except the arbitrary format were ranked as the most preferred at least once, it is worthwhile to generate seven icon formats for a given function and chose the most preferred based on the ranking test result. The participatory design and ranking test evaluation approach can be applied for the design and evaluation of visual icons in other application contexts.

Management of Systemic Steroid in HIV Patient with Toxoplasma Papillitis.

BACKGROUND: Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. Ocular manifestations are seen in both congenital and acquired toxoplasmosis. These can include focal inflammation within or around the optic nerve head (papillitis). Purpose of this study is evaluating the efficacy of systemic steroid in HIV patient with toxoplasma papillitis. CASE PRESENTATION: We present a case report of a male, 46 years old with a decrease of visual acuity on the right eye for three weeks before admission to the hospital. An ophthalmology examination showed visual acuity of the right eye 1/60, mild dilatation of the pupil and posterior synechiae, vitreous was hazy, and fundus examination showed optic nerve head not well demarcated and hyperaemic with the good retina and macula reflex. Laboratory examination showed reactive anti-Toxoplasma immunoglobulin G. Patient had been treated with antiretroviral and anti-Toxoplasma drugs, then he was given steroid 250 mg intravenously four times per day for three days and tapering off orally. Visual acuity on the right eye improve from 1/60 became 6/60 after use of steroid on the third day. DISCUSSION: Steroid can improve visual acuity for toxoplasma papillitis in this patient. But the long term and close follow up in steroid therapy is needed.

The perceived quality of in-vehicle auditory signals: a structural equation modelling approach.

The current study applied Structural Equation Modelling to analyse the relationship among pitch, loudness, tempo and timbre and their relationship with perceived sound quality. Twenty-eight auditory signals of horn, indicator, door open warning and parking sensor were collected from 11 car brands. Twenty-one experienced drivers were recruited to evaluate all sound signals with 11 semantic differential scales. The results indicate that for the continuous sounds, pitch, loudness and timbre each had a direct impact on the perceived quality. Besides the direct impacts, pitch also had an impact on loudness perception. For the intermittent sounds, tempo and timbre each had a direct impact on the perceived quality. These results can help to identify the psychoacoustic attributes affecting the consumers' quality perception and help to design preferable sounds for vehicles. In the end, a design guideline is proposed for the development of auditory signals that adopts the current study's research findings as well as those of other relevant research. Practitioner Summary: This study applied Structural Equation Modelling to analyse the relationship among pitch, loudness, tempo and timbre and their relationship with perceived sound quality. The result can help to identify psychoacoustic attributes affecting the consumers' quality perception and help to design preferable sounds for vehicles.

Psychophysical evaluation of auditory signals in passenger vehicles.

Twenty-one experienced drivers were recruited for the evaluation of sounds of four functions (horn, indicator, door open warning, and parking sensor) made by 11 car brand names. Each participant was required to evaluate all of the above sound signals by a pair-comparison test. After the comparison test, each participant was shown his/her pair-comparison result and was asked to comment on their preference and appropriateness of a sound. The physical properties and interview data were compared and summarized to propose design recommendations. Our results indicate that complex tones and a fundamental frequency around 450 Hz were most preferred for horns while for indicators the preferred sounds had a higher dominant frequency [corrected].To reduce monotony, the indicators with double clicks and an OFF time interval of between 330 and 400 ms between two clicks were most preferred. Regarding door warning sounds, the waveform starting with a higher intensity then fading towards zero intensity is most preferred while for parking sensors, sounds beginning with a longer OFF time (about 500 ms) and having 3 or 4 distinctive tempo variations were most preferred. The relationship between pleasurability and pitch, loudness, and the tempo of sound signals basically followed an inverted-U function. Sound designers should avoid using very extreme parameter values when generating sound for a given function.

Effect of cholecalciferol on GLUT4 expression in adipocyte of diabetic rats / Journal of the ASEAN Federation of Endocrine Societies

@#This research was conducted to examine the effect of cholecalciferol on fasting blood glucose (FBG), adipocyte diameter and glucose transporter (GLUT) 4 expression in adipocytes of diabetic rats. Nineteen male Wistar strain diabetic rats were divided into 4 groups (K, X1, X2 and X3). Cholecalciferol was administered in the amount of 6.25 μg/kg in X1, 12.5 μg/kg in X2 and 25 μg/kg in X3 per orem, once daily for 14 days. Group K received the placebo. There were no significant differences in FBG (p=0.199) and adipocyte diameter (p=0.218) between groups but there were significant differences in the expression of GLUT4 between control and treatment groups. Thus, cholecalciferol can increase GLUT4 expression in adipocyte without altering FBG and adipocyte diameter of diabetic rats.

Graphical fault tree analysis for fatal falls in the construction industry.

The current study applied a fault tree analysis to represent the causal relationships among events and causes that contributed to fatal falls in the construction industry. Four hundred and eleven work-related fatalities in the Taiwanese construction industry were analyzed in terms of age, gender, experience, falling site, falling height, company size, and the causes for each fatality. Given that most fatal accidents involve multiple events, the current study coded up to a maximum of three causes for each fall fatality. After the Boolean algebra and minimal cut set analyses, accident causes associated with each falling site can be presented as a fault tree to provide an overview of the basic causes, which could trigger fall fatalities in the construction industry. Graphical icons were designed for each falling site along with the associated accident causes to illustrate the fault tree in a graphical manner. A graphical fault tree can improve inter-disciplinary discussion of risk management and the communication of accident causation to first line supervisors.

Matching performance of vehicle icons in graphical and textual formats.

The current research classified 82 vehicle icons into seven categories (image-related, concept-related, semi-abstract, arbitrary, abbreviation, word, and combined) for their matching accuracy, matching sequence, and matching time. These data can be compared and used as a framework for future icon development. Forty participants, all with a university degree, took part in this experiment. Half of the participants had intensive driving experience, while the other half never driven a car. The results indicated that on average, word icons had a significantly greater matching accuracy than the other icon formats; ranging from 4.7 to 20.8% difference. Regarding the matching sequence, participants matched image-related icons before other icon formats. Arbitrary and combined icons took significantly longer to match than other icon formats by 1.4-6.2 s. Based on the high matching accuracy (86.3%) and high ratings on subjective design features, word format can be used for functions describable using simple English for users with English reading ability. Confusion matrices showed that 63.2% of the misunderstandings were caused by similarity in format or function.