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1.
Skinmed ; 21(3): 208-210, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37634110

RESUMO

An 11-year-old boy presented with serial autoamputations of the right 4th and 5th toes during the past 6 years. This was associated with sensory loss on the right leg and development of constriction bands around the right 2nd and 3rd digits for the past 5 months. For a year, the patient had been treated with paucibacillary, multi-drug therapy (PB-MDT) with a presumptive diagnosis of leprosy. He was born from a nonconsanguinous marriage and the birth was uneventful. The developmental milestones were normal, and no family history of any congenital anomalies was reported.


Assuntos
Ainhum , Masculino , Humanos , Criança , Pele , Extremidade Inferior , Dedos do Pé
2.
Pan Afr Med J ; 42: 261, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36338563

RESUMO

Pigmented dermatofibromasarcoma protuberans (DFSP) is a rare variant of DFSP which is an intermediate-grade tumour due to its tendency for local reccurence. Morphology of this variant impose a differential diagnosis that is must know for a pathologist. We describe two cases that presented with pigmented papulo-nodular form involving back and lower limb in middle aged to an elderly female. Histopathology coupled with immunohistochemistry yielded daignosis of Bedner tumour. A surgical histopathologist needs to have knowledge of all differential of pigmented neoplasm of skin just to ensure not to skip this rare entity.


Assuntos
Dermatofibrossarcoma , Neoplasias Cutâneas , Pessoa de Meia-Idade , Idoso , Feminino , Humanos , Dermatofibrossarcoma/patologia , Neoplasias Cutâneas/patologia , Pele/patologia , Imuno-Histoquímica , Diagnóstico Diferencial
5.
Cureus ; 13(8): e17514, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34603886

RESUMO

Introduction Hansen's disease is a chronic infectious disease caused by Mycobacterium leprae. India declared the elimination of leprosy in December 2005, but a slow resurgence of the disease still continues in several parts of India. The diagnosis of leprosy is primarily clinical but slit-skin smear microscopy aids in an accurate diagnosis. There are very few studies on clinico-bacteriological patterns of leprosy at this post-elimination phase. Aim This study aimed to analyze the clinical and bacteriological findings of newly diagnosed cases of Hansen's disease in the post-elimination era. Materials and methods This is a descriptive, hospital-based, retrospective study of newly diagnosed cases of Hansen's disease, enrolled in the Hansen's disease clinic attached to the dermatology outpatient department (OPD) of a tertiary care hospital in North India. A retrospective chart review of newly diagnosed cases of leprosy for a period of one year was done. Information about demographics, clinical characteristics, spectrum of disease, and slit skin smear data of patients were collected. Statistical analysis was performed using SPSS Version 16.0 (Chicago, IL, SPSS Inc.). Result A total of 116 patients were included of which 68.1% (79) were males. The age of patients ranged from 7 to 72 years and children (<15 years) constituted 6% (7/116) of all cases. The most common clinical spectrum was borderline lepromatous leprosy 37.9% (44/116) followed by lepromatous leprosy 32.8% (38/116). Out of 116 cases, 39.6% of cases showed slit-skin smear positivity. Conclusion The study brings forth evidence on the slow re-emergence of leprosy in India. In this study, multibacillary cases outnumber the paucibacillary cases; also, childhood cases were encountered indicating active community spread of the disease in the "post-elimination era." There is an urgent need to step up the surveillance for Hansen's disease to curb the further spread of the bacilli in the community.

12.
Int J Mycobacteriol ; 9(2): 220-222, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32474549

RESUMO

Tuberculosis verrucosa cutis (TBVC) is a common paucibacillary form of cutaneous tuberculosis caused by exogenous reinfection in previously sensitized individuals. The typical morphology is usually observed as a single verrucous plaque with inflammatory borders mostly on the hands, knees, ankle, and buttocks; however, several atypical morphologies of the lesions have also been described. TBVC occurring in sporotrichoid pattern is relatively rare. We report a case of a rare sporotrichoid presentation of TBVC in a 38-year-old male patient in the absence of any primary tuberculous focus.


Assuntos
Pele/patologia , Tuberculose Cutânea/diagnóstico , Adulto , Antituberculosos/uso terapêutico , Mãos/microbiologia , Mãos/patologia , Humanos , Masculino , Pele/microbiologia , Resultado do Tratamento , Tuberculose Cutânea/classificação , Tuberculose Cutânea/tratamento farmacológico
13.
J Dtsch Dermatol Ges ; 17(10): 1063-1065, 2019 Oct.
Artigo em Alemão | MEDLINE | ID: mdl-31631538
16.
Dermatol Pract Concept ; 8(1): 43-47, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29445574

RESUMO

Verrucous hemangioma (VH) is a rare, congenital and localized vascular malformation, which usually presents as warty, bluish, vascular papules, plaques, or nodules, mainly on the lower extremities. Linear presentation of the disease is rare. A deep biopsy is necessary to confirm the clinical diagnosis by histopathological examination, with dermoscopy acting as a useful tool for evaluating the precise vascular structure. Here, we report on a 13-year-old female child with linear VH presenting over her foot since infancy and dermoscopic findings of VH along with the clinical-pathologic features.

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