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Toxicon ; 180: 43-48, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32298663

RESUMO

Zearalenone, an oestogenic mycotoxin produced by Fusarium sp., occurs naturally in agricultural commodities. Economic losses and health concerns associated to mycotoxins has attracted research interest towards exploring novel approaches to detoxify mycotoxin-contaminated food and feed. The aim of the present work was to study the ability of 11 aflatoxin-degrading Bacillus strains to degrade ZEA. In addition, a qualitative assessment of protease, amylase and cellulase activity of the studied Bacillus strains was made. All strains were able to degrade 58-96.9% ZEA after 72 h. Toxicity towards Artemia salina was significantly reduced (P < 0.0001). Degradation extracts fluorescence decreased 50% indicating a probable cleavage of the lactone ring. Strains RC1A, RC3A and RC6A showed a remarkable enzymatic activity, showing potential to be used as feed additives.


Assuntos
Aflatoxinas/metabolismo , Amilases/metabolismo , Bacillus/metabolismo , Celulases/metabolismo , Peptídeo Hidrolases/metabolismo , Zearalenona/metabolismo , Agricultura , Inativação Metabólica
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