RESUMO
PURPOSE: Chemotherapy treatment can lead to cardiovascular toxicity and physical impairment prior to autologous hematopoietic stem cell transplantation (auto-HSCT). Cardiovascular adjustments during exercise and the exercise capacity remain unknown in patients prior to auto-HSCT. Thus, the hemodynamic responses during exercise and exercise capacity were evaluated using a novel effort test in patients prior to auto-HSCT. METHODS: Thirty patients prior to auto-HSCT (BMT group: 44.6 ± 14.1 years) and 23 control participants (CON group: 43.9 ± 16.6 years) performed the 6-Minute Step Test (6MST) to assess their exercise capacity and the hemodynamic responses during exercise. Systolic and diastolic blood pressure (SBP and DBP), heart rate (HR), and oxygen saturation (SpO2) were measured during the test. Rate-pressure product (RPP) was calculated multiplying SBP by HR. The highest HR value recorded during the test was compared with the maximum HR predicted by age and was used as % of maximum HR (%HRmax). RESULTS: The number of steps up and down performed by the BMT group was lower than CON (108.8 ± 25.3 vs. 127.5 ± 34.4 steps, P = 0.02). The BMT group showed a higher magnitude of increase in SBP and RPP during the 6MST when compared to CON (ΔSBP: 18.5 ± 11.45 vs. 8.30 ± 18.46 mmHg, P = 0.01; and ΔRPP: 8197.3 ± 3829.1 vs. 6170.9 ± 3568.9 mmHg beats min-1, P = 0.05). The BMT group exhibited higher SpO2 and HR values throughout the protocol (P < 0.05), reaching a higher %HRmax than CON group (76.9 ± 9.6 vs. 66.4 ± 8.9%, P < 0.01). CONCLUSIONS: Patients with indication for auto-HSCT have exacerbated chronotropic and pressor responses during exercise and reduced exercise capacity in the 6MST.
Assuntos
Exercício Físico/fisiologia , Transplante de Células-Tronco Hematopoéticas/métodos , Hemodinâmica/fisiologia , Neoplasias/fisiopatologia , Condicionamento Pré-Transplante/métodos , Transplante Autólogo/métodos , Adulto , Feminino , Humanos , MasculinoRESUMO
A prática de exercícios físicos, como o método Pilates (MP), tem sido considerada como terapia coadjuvante na manutenção da autonomia e independência de idosos. O objetivo do estudo foi analisar, através de uma revisão sistemática, a influência do MP na capacidade funcional de idosos. O MP, de acordo com os trabalhos analisados, promoveu melhoras significativas na autonomia funcional de idosos. Entretanto, ressalta-se a necessidade de mais estudos, visto que trabalhos com essa temática são escassos.
The practice of physical exercises, such as the Pilates (MP) method, has been considered as adjuvant therapy in maintaining autonomy and independence of the elderly. The objective of the study was to analyze, through a systematic review, the influence of MP on the functional capacity of the elderly. The MP, according to the analyzed works, promoted significant improvements in the functional autonomy of the elderly. However, there is a need of more studies, since works with this subject are scarce.
La práctica de ejercicios físicos, como el método Pilates (MP), ha sido considerado como terapia coadyuvante en el mantenimiento de la autonomía e independencia de ancianos. El objetivo del estudio fue analizar, a través de una revisión sistemática, la influencia del MP en la capacidad funcional de ancianos. El MP, de cuerdo con los trabajos analizados, promovió mejoras significativas en la autonomía funcional de ancianos. Sin embargo, se resalta la necesidad de más estudios, ya que trabajos con esa temática son escasos.
