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Blood Cells Mol Dis ; 37(1): 8-11, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-16750922

RESUMO

A cross-sectional prevalence study of anemia was undertaken on 412 pregnant women in northeast Thailand during January 2003 to May 2004. With standardized diagnostic protocols and the CDC criteria of anemia [hemoglobin (Hb) < 11 g/dl at < or = 12 weeks of gestation and Hb < 10.5 g/dl at < or = 20 weeks of gestation], 71 (17.2%) subjects were anemic. Of these, 42 (59.2%) subjects had thalassemia, 5 (7.0%) had iron deficiency, 18 (25.4%) had combined thalassemia and iron deficiency and 6 (8.5%) had no thalassemia nor iron deficiency. Adjusted logistic regression analyses indicated that various thalassemia genotypes were significantly related to anemia, while homozygous Hb E had the highest risk with an odds ratio (OR) of 44.8 (95% CI 12.6-159.7). In comparison, iron deficiency demonstrated a much lower risk with OR of 3.1 (95% CI 1.4-6.8). This finding suggests that the contribution of iron deficiency to pregnancy associated anemia in this region is low.


Assuntos
Anemia/etiologia , Hemoglobinopatias/complicações , Complicações Hematológicas na Gravidez/etiologia , Talassemia/complicações , Adulto , Anemia/genética , Estudos Transversais , Feminino , Genótipo , Hemoglobina E/genética , Hemoglobinopatias/genética , Humanos , Deficiências de Ferro , Razão de Chances , Gravidez , Prevalência , Tailândia/epidemiologia , Talassemia/genética
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