Research Progress, Hotspots, and Trends of Using BIM to Reduce Building Energy Consumption: Visual Analysis Based on WOS Database.

With the development of engineering technology, building information modeling (BIM) has attracted more and more attention and has been studied by many experts on building energy consumption in recent years. It is necessary to analyze and forecast the application trend and prospect of BIM technology in building energy consumption. Based on 377 articles published in the WOS database, this study adopts the technique of combining scientometrics and bibliometrics to obtain relevant research hotspots and quantitative analysis results. The findings demonstrate that the building energy consumption field has made extensive use of BIM technology. However, there are still some limitations that can be improved, and the use of BIM technology in construction renovation projects should be emphasized. This study can help readers better understand the application status of BIM technology and its trajectory of development with regard to building energy consumption, providing a valuable reference for future research.

Acute stress enhances learning and memory by activating acid-sensing ion channels in rats.

Acute stress has been shown to enhance learning and memory ability, predominantly through the action of corticosteroid stress hormones. However, the valuable targets for promoting learning and memory induced by acute stress and the underlying molecular mechanisms remain unclear. Acid-sensing ion channels (ASICs) play an important role in central neuronal systems and involves in depression, synaptic plasticity and learning and memory. In the current study, we used a combination of electrophysiological and behavioral approaches in an effort to explore the effects of acute stress on ASICs. We found that corticosterone (CORT) induced by acute stress caused a potentiation of ASICs current via glucocorticoid receptors (GRs) not mineralocorticoid receptors (MRs). Meanwhile, CORT did not produce an increase of ASICs current by pretreated with GF109203X, an antagonist of protein kinase C (PKC), whereas CORT did result in a markedly enhancement of ASICs current by bryostatin 1, an agonist of PKC, suggesting that potentiation of ASICs function may be depended on PKC activating. More importantly, an antagonist of ASICs, amiloride (10 µM) reduced the performance of learning and memory induced by acute stress, which is further suggesting that ASICs as the key components involves in cognitive processes induced by acute stress. These results indicate that acute stress causes the enhancement of ASICs function by activating PKC signaling pathway, which leads to potentiated learning and memory.