Postoperative effects on lower third molars of using mouthwashes with super-oxidized solution versus 0.2% chlorhexidine gel: A randomized double-blind trial.

BACKGROUND: The main objective of the present study is to evaluate the effects and possible benefits with regard to the postoperative period of lower third molar extractions, comparing the intraalveolar application of a bioadhesive gel of 0.2% chlorhexidine (CHX) to the use of a mouthwash with a super-oxidized solution, (SOS) Dermacyn® Wound Care (Oculus Innovative Sciences lnc., California, USA). MATERIAL AND METHODS: A randomized double-blind study was carried out in 20 patients with a split-mouth design, with a total of 40 extractions of symmetrically impacted bilateral lower third molars. Patients were divided into two groups, a control group (C = 20) and an experimental group (D = 20). Any infectious complications, wound healing, plaque accumulation in the stitches, and presence of trismus and inflammation were evaluated using the distance between different facial points, at three, eight, and fifteen days after extraction. Pain, swelling, and amount of analgesics taken were evaluated using the VAS scale throughout the 15 days following extraction. Tolerance to treatment was evaluated using a verbal scale. Results were statistically compared using the Student's t- and chi-squared tests. RESULTS: No statistically significant differences were found between the two groups with regard to infectious complications, swelling, or wound healing. Use of analgesics and self-reported pain levels were slightly lower in the experimental group than in the control group during days 6 and 7 of the study (p < 0.05). The global treatment tolerance was satisfactory and similar in both groups. CONCLUSIONS: Both CHX and SOS are effective at improving the postoperative period after extraction of lower third molars.

Modificaciones en la composición del fluido crevicular en pacientes en tratamiento ortodóncico / Composition changes in gingival crevicular fluid during orthodontic treatment

El fluido crevicular, exudado inflamatorio que se encuentra en el surco gingival, lo integran distintos constituyentes derivados de la placa microbiológica, células inflamatorias y tejido del hospedador que son marcadores diagnósticos de la destrucción de los tejidos en la enfermedad periodontal. El objetivo de esta revisión es describir las modificaciones que sufre el fluido crevicular como consecuencia de la inflamación de los tejidos periodontales cuando se inicia un tratamiento ortodóncico. Resultados: La aplicación de aparatología ortodóncica induce la liberación y el aumento en el fluido crevicular de distintos mediadores bioquímicos: IL-1 beta, IL-8, factor de necrosis tumoral alfa o prostaglandinaE2 y de neuropéptidos como la sustancia P. Los niveles de fosfatasa ácida y alcalina y lactato deshidrogenasa aumentan también con la inflamación. Conclusión: El análisis de los componentes del fluido crevicular es un método no invasivo válido para el estudio de la respuesta celular del ligamento periodontal durante el tratamiento ortodóncico (AU)

Gingival crevicular fluid, an inflammatory exudate, located in the gingival groove is integrated by different components that come from microbiologic plaque, inflammatory cells and tissue, these parameters are used to diagnose tissue loss in the subject’s periodontal disease. The aim of this review is to describe the changes in crevicular fluid as a result of periodontal tissues´ inflammation as orthodontic treatment begins. Results: A significant release and increment of different biochemical substances (Interleukin-1b, interleukin-8, TNF, prostaglandin E2and neuropeptides such as substance P) is produced as the treatment evolves. Inflamation raises alkaline phosphatase, acid phosphatase and lactate dehydrogenase levels. Conclusion: Crevicular fluid’s analysis is a useful-non-invasive approach to study the periodontal ligament response to orthodontic treatment (AU)