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1.
PLoS Negl Trop Dis ; 17(11): e0011372, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37956163

RESUMO

Mycetomas are endemic diseases in tropical and sub-tropical countries of Africa, Asia and America, mainly affecting rural populations living below the poverty line. We report a particular case of a mycetoma associated with pregnancy whose evolution was good, but at the cost of significant financial expenses. This was a 39-year-old woman who developed a fungal mycetoma due to Madurella mycetomatis from the ingunocrural region. The patient had to develop several previous pregnancies on this site of mycetoma, the outcome of which was favorable. The last pregnancy was accompanied by an aggravation of the mycetoma in the form of polyfistulized inflammatory swelling of the right inguino-crural region emitting black grains. Magnetic Resonance Imaging (MRI) of the region showed invasion of the adductor muscles at the level of the root of the thigh on its antero-internal side with no sign of pelvic extension or underlying bone lesion. The patient was treated by surgery associated with antifungal treatment. The evolution was favorable for pregnancy and mycetoma.


Assuntos
Madurella , Micetoma , Feminino , Humanos , Gravidez , Adulto , Micetoma/diagnóstico , Micetoma/tratamento farmacológico , Micetoma/cirurgia , Antifúngicos/uso terapêutico , África , Ásia
2.
Int J Dermatol ; 59(2): 137-142, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31630401

RESUMO

BACKGROUND: The pathogenesis of lichen planus (LP) is mostly autoimmune, while psychological and infectious factors are recognized to trigger or aggravate the disease. An association with diabetes is reported. Our objective was to determine the epidemio-clinical characteristics of LP and its associated factors. METHODS: This multicentric, prospective study was conducted over a 6-month period. The histopathology was only performed for atypical forms. Patients with a notion of drug intake before the rash were excluded. Anti-hepatitis C Virus (HCV) antibodies screening was systematical in case of mucosal damage. The data were analyzed using the SPSS IBM 20 software. RESULTS: The average age was 38 years. Women represented 84.6% (n = 66) of the studied population. The patients were married in 61.5%. Obesity or overweight status was noted in 41%. A marital or relational conflict was found in 25.6%. History of LP was reported in 24.4% (n = 19). Pruritus was found in 96.2%. The locations were as follows: skin (97.4%), mucous membranes (15.4%), and hair and nails (5.1%). Lesions were diffuse in 56.4%. The clinical forms were as follows: typical (52.6%), erythematosquamous (17%), warty (14.5%), pigmented (14.5%), and blaschkolinear (one case). Histopathology confirmed the diagnosis of LP in 91.4%. Blood sugar level was high in one case. Hepatitis B surface antigen (HBsAg) was positive in 3.03%. Anti-HIV and anti-HCV antibodies were negative. CONCLUSION: Lichen planus is a relatively rare disease in sub-Saharan Africa and is seen more in adults. The clinical manifestations are polymorphic, but the mucosal damage is rarely isolated.


Assuntos
Líquen Plano/epidemiologia , Líquen Plano/patologia , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Estudos Transversais , Feminino , Antígenos de Superfície da Hepatite B/sangue , Humanos , Relações Interpessoais , Líquen Plano/complicações , Líquen Plano/psicologia , Masculino , Estado Civil , Pessoa de Meia-Idade , Obesidade/epidemiologia , Estresse Ocupacional/epidemiologia , Estudos Prospectivos , Prurido/etiologia , Senegal/epidemiologia , Pigmentação da Pele , Adulto Jovem
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