Counseling increases immediate postpartum Long-Acting Reversible Contraception (LARC) acceptability in Hispanic women.

OBJECTIVE: Determine if providing basic contraceptive counseling during prenatal visits increases pregnant Hispanic women's acceptance of immediate postpartum long-acting reversible contraception (LARC). STUDY DESIGN: Respondents completed a short survey consisting of demographic information, an acculturation scale, and perceptions of immediate postpartum LARC use. After reading a brief educational excerpt on intrauterine devices (IUDs) and the subdermal contraceptive implant, LARC acceptability was reassessed. The study included 198 Hispanic women, ages 14 and older, in the 2nd or 3rd trimester of pregnancy receiving care at an academic practice along the United States-Mexico border in West Texas. Analysis was performed using a McNemar test, univariate and multivariable relative risk (RR) regression. RESULTS: Prior to an educational intervention, 34.5% of respondents indicated that they were planning to use immediate postpartum LARC. Following the educational intervention, 74.5% of respondents indicated they would consider a postpartum LARC. The pre/post comparison on the intent to use postpartum LARC showed that a significant number of respondents changed their intention to use LARC after reading the educational intervention (RR= 2.54, p<0.0001). LARC acceptability was high among single women, those less than 25-years-old, women with current unintended pregnancies, and women using a contraceptive method that failed when they became pregnant. CONCLUSION: In communities with a high proportion of Hispanic women, postpartum contraceptive counseling is crucial for patient education and family planning. When women are provided with brief, structured contraceptive counseling during prenatal visits, they are more willing to consider use of an immediate postpartum LARC for their future family planning.

Pregnancy Inhibits Mammary Carcinogenesis by Persistently Altering the Hypothalamic-Pituitary Axis.

Early full-term pregnancy is known to reduce the lifetime risk of breast cancer. Although the phenomenon of parity-induced protection is well-established, the physiological mechanisms involved in this protection are not clear. Earlier reports have shown that pregnancy results in alterations of hormone levels. How pregnancy affects hypothalamic hormones and how the change, if any, influences breast cancer is not well understood. Seven-week-old female Lewis rats were given N-methyl-N-nitrosourea. Two weeks post carcinogen exposure, a set of females were housed with males to generate the parous rats and another set of rats served as the nulliparous controls. Mammary tumorigenesis was assessed for 9 months. Hypothalamic and pituitary levels of hormones were measured at various timepoints. Further, animals were also challenged with growth hormone and prolactin secretagogues to test the effect of pregnancy on the hypothalamic-pituitary hormonal axis. Persistent alterations in the level of growth hormone-releasing hormone, thyrotropin releasing hormone, dopamine, and somatostatin in the hypothalamus of parous animals was observed. Further, we also observed that pregnancy had a significant effect on the pituitary gland and its response to growth hormone and prolactin secretagogues. Our studies using the rodent model system demonstrate that pregnancy could be reducing the risk of breast cancer by persistently altering the hypothalamic-pituitary axis, which could have implications for breast cancers in humans as well.