Histological examination of tooth-derived biomaterials obtained from different devices.

AIM: The aim of the present study was to investigate the histological differences between samples processed by different devices and to confirm safe clinical application of different dentin matrix obtained from three devices: BonMaker, Tooth Transformer, and Smart Dentin Grinder in regeneration of maxillary defects. RESEARCH DESIGN: The study involved 39 patients with two-wall or three-wall defects who underwent bone augmentation procedures in the maxilla using dentin matrix grafts from the BonMaker, Tooth Transformer, and Smart Dentin Grinder devices. Histological examination was conducted on samples obtained from patients who received each device. In this article, histological samples have been selected and are presented. RESULTS: In all patients, bone defects were successfully augmented with ground dentin matrix. The histological examination revealed no inflammation and a good connection between the bone and dentin matrix and clinically all patients were qualified for implant placement. CONCLUSIONS: After comparing the BonMaker, Tooth Transformer, and Smart Dentin Grinder devices in our practice, we concluded that all these systems have the potential for obtaining regenerative material from the patient's teeth.

Comparison of clinical efficacy of three different dentin matrix biomaterials obtained from different devices.

AIM: The aim of the present study was to propose the clinical efficacy of the different dentin matrix obtained from three devices (BonMaker, Tooth Transformer, and Smart Dentin Grinder) and to show their morphological, physical, and biochemical characteristics using scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) spectroscopy, and Raman spectroscopy. RESEARCH DESIGN AND METHODS: The study included 70 patients who underwent bone augmentation using the BonMaker, Tooth Transformer, and Smart Dentin Grinder devices. In addition, 84 implants were placed. Furthermore, four samples, one for each device and one non-demineralized control, were analyzed with scanning electron microscopy (SEM), energy-dispersive X-ray analysis, and Raman spectroscopy. RESULTS: In all patients, augmentation of bone defects with ground dentin matrix was successful, and implants showed correct osseointegration. The morphological organization, the chemical composition, and the presence of organic molecules in the dentin samples processed by the three different devices were demonstrated using SEM, energy-dispersive X-ray analysis, and Raman spectroscopy. CONCLUSIONS: Comparing BonMaker, Tooth Transformer, and Smart Dentin Grinder devices in our practice, we concluded that these systems, even with different structural and chemical differences of the dentin granules, have a comparable potential for obtaining regenerative material from the patient's own teeth.

Socket preservation or guided bone regeneration - a case report.

The greatest challenge of modern implantology is the loss of bone tissue in esthetic region of maxilla and mandible. Significant bone changes caused for example by cysts, unerupted teeth or traumatic extraction often provoke bilateral or trilateral bone defects. Thanks to the possibility of applying demineralized dentin and dentin blocks gained from extracted teeth of the patient, it is possible to successfully regenerate bone tissue especially in the esthetic zone. AIM: The aim of the study was to present a case of a patient who underwent bone augmentation for implantation. In addition, a review of the literature illustrating the effectiveness of autogenous bone graft material derived from ground teeth in augmentation procedures was performed. A CASE REPORT: The paper presents a case of a 26-year-old man in whom bone defect was augmented with material derived from dentin blocks and partially demineralized dentin processed in the BonMaker device after extraction of the root of tooth 11. A systematic review of literature was conducted analyzing articles published between 1975 and 2020. From 80 articles, 25 were selected for this study. CONCLUSIONS: The presented case and the systematic review of literature indicate that tooth-derived bone graft material prepared from extraction can effectively restore alveolar bone defect. The results we get so far are very satisfying. Further studies should be performed to confirm the osteogenic effects and safety use of this tooth based graft material.