Kindchenschema and cuteness elicit interest in caring for and playing with young children, but less so when children are masked.

Cuteness in the young has long been theorized to elicit care and protection. Most research on this topic has focused on human infants, despite theories suggesting that cuteness may elicit broader social interest that could support learning and development beyond infancy. In four experiments (N = 531 adults, 98 children), we tested whether 'kindchenschema'-facial features associated with cuteness-and perceived cuteness elicit interest in playing with and caring for children, and whether masks disrupt these processes. Participants viewed images of children's faces, masked or unmasked. Kindchenschema correlated with perceived cuteness and age, and these variables predicted adults' interest in playing with and caring for children. Masks did not reduce cuteness ratings or interest in children, although they weakened relations between perceived cuteness and interest, and between perceived age and interest. Cuteness and related signals may guide adults' interactions with children, fostering learning and development.

What are the kids doing? Exploring young children's activities at home and relations with externally cued executive function and child temperament.

Young children spend a lot of time at home, yet there is little empirical research on how they spend that time and how it relates to developmental outcomes. Prior research suggests less-structured time-where children practice making choices and setting goals-may develop self-directed executive function in 6-year-olds. But less-structured time may be related to executive function for other reasons-for example, because it provides opportunities to acquire conceptual knowledge relevant to using executive function on tasks. We thus tested the possibility that less-structured time is also related to younger children's externally cued executive function. In this remote online study, caregivers of 93 3- to 5-year-olds indicated the amount of time their child was typically spending in various activities while at home during the early phase of the COVID-19 pandemic. Activities were categorized as structured (primarily lessons with specific goals defined by adults or an app), less-structured (wide range of activities permitting choice and interaction with caregiver), passive (e.g., watching TV or videos), and primarily physical (e.g., bike riding). Children's externally cued executive function was assessed via the Dimensional Change Card Sort (DCCS). Time and variety in less-structured activities were related to successful switching on the DCCS, controlling for age, family income, caregiver education, and verbal knowledge. Caregivers were more involved in less-structured versus structured activities. Caregiver ratings of children's temperament were related to how children's time was spent. These findings suggest several new avenues for studying young children's activities at home and their relations with developmental outcomes. A video abstract of this article can be viewed at https://youtu.be/3aGmpSnjuCs.

Rethinking Executive Function and Its Development.

Research on executive function in early childhood has flourished in recent years. Much of this work is premised on a view of development of executive function as the emergence of a set of domain-general component processes (e.g., working memory updating, inhibitory control, shifting). This view has shaped how we think about relations between executive function and other aspects of development, the role of the environment in executive-function development, and how best to improve executive function in children who struggle with it. However, there are conceptual and empirical reasons to doubt that executive function should be defined in this way. I argue that the development of executive function is better understood as the emergence of skills in using control in the service of specific goals. Such goals activate and are influenced by mental content such as knowledge, beliefs, norms, values, and preferences that are acquired with development and are important to consider in understanding children's performance on measures of executive function. This account better explains empirical findings than the component-process view; leads to specific, testable hypotheses; and has implications for theory, measurement, and interventions.

Group Influences on Engaging Self-Control: Children Delay Gratification and Value It More When Their In-Group Delays and Their Out-Group Doesn't.

Self-control emerges in a rich sociocultural context. Do group norms around self-control influence the degree to which children use it? We tested this possibility by assigning 3- to 5-year-old children to a group and manipulating their beliefs about in-group and out-group behavior on the classic marshmallow task. Across two experiments, children waited longer for two marshmallows when they believed that their in-group waited and their out-group did not, compared with children who believed that their in-group did not wait and their out-group did. Group behavior influenced children to wait more, not less, as indicated by comparisons with children in a control condition who were assigned to a group but received no information about either groups' delay behavior (Experiment 1). Children also subsequently valued delaying gratification more if their in-group waited and their out-group did not (Experiment 2). Childhood self-control behavior and related developmental outcomes may be shaped by group norms around self-control, which may be an optimal target for interventions.

Using language to get ready: Familiar labels help children engage proactive control.

A key developmental transition is the ability to engage executive functions proactively in advance of needing them. We tested the potential role of linguistic processes in proactive control. Children completed a task in which they could proactively track a novel (target) shape on a screen as it moved unpredictably amid novel distractors and needed to identify where it disappeared. Children almost always remembered which shape to track, but those who learned familiar labels for the target shapes before the task had nearly twice the odds of tracking the target compared with those who received experience with the targets but no labels. Children who learned labels were also more likely to spontaneously vocalize labels when the target appeared. These findings provide the first evidence of a causal role for linguistic processes in proactive control and suggest new ideas about how proactive control develops, why language supports a variety of executive functions, and how interventions might best be targeted.

Getting ready to use control: Advances in the measurement of young children's use of proactive control.

A key developmental transition in executive function is in the temporal dynamics of its engagement: children shift from reactively calling to mind task-relevant information as needed, to being able to proactively maintain information across time in anticipation of upcoming demands. This transition is important for understanding individual differences and developmental changes in executive function; however, methods targeting its assessment are limited. We tested the possibility that Track-It, a paradigm developed to measure selective sustained attention, also indexes proactive control. In this task children must track a target shape as it moves unpredictably among moving distractors, and identify where it disappears, which may require proactively maintaining information about the target or goal. In two experiments (5-6 year-olds, Ns = 33, 64), children's performance on Track-It predicted proactive control across two established paradigms. These findings suggest Track-It measures proactive control in children. Theoretical possibilities regarding how proactive control and selective sustained attention may be related are also discussed.

Beyond personal control: The role of developing self-control abilities in the behavioral constellation of deprivation.

We agree with Pepper & Nettle that personal control is important in understanding people's willingness to engage in future-oriented behavior. However, this does not imply that self-control abilities play no role, for self-control abilities do influence whether individuals engage in future-oriented behavior. Personal control may also shape the development of self-control abilities, so contrasting the two may be a false dichotomy.

Seeing conflict and engaging control: Experience with contrastive language benefits executive function in preschoolers.

Engaging executive function often requires overriding a prepotent response in favor of a conflicting but adaptive one. Language may play a key role in this ability by supporting integrated representations of conflicting rules. We tested whether experience with contrastive language that could support such representations benefits executive function in 3-year-old children. Children who received brief experience with language highlighting contrast between objects, attributes, and actions showed greater executive function on two of three 'conflict' executive function tasks than children who received experience with contrasting stimuli only and children who read storybooks with the experimenter, controlling for baseline executive function. Experience with contrasting stimuli did not benefit executive function relative to reading books with the experimenter, indicating experience with contrastive language, rather than experience with contrast generally, was key. Experience with contrastive language also boosted spontaneous attention to contrast, consistent with improvements in representing contrast. These findings indicate a role for language in executive function that is consistent with the Cognitive Complexity and Control theory's key claim that coordinating conflicting rules is critical to overcoming perseveration, and suggest new ideas for testing theories of executive function.

Young Children Detect and Avoid Logically Inconsistent Sources: The Importance of Communicative Context and Executive Function.

The reported research tested the hypothesis that young children detect logical inconsistency in communicative contexts that support the evaluation of speakers' epistemic reliability. In two experiments (N = 194), 3- to 5-year-olds were presented with two speakers who expressed logically consistent or inconsistent claims. Three-year-olds failed to detect inconsistencies (Experiment 1), 4-year-olds detected inconsistencies when expressed by human speakers but not when read from books, and 5-year-olds detected inconsistencies in both contexts (Experiment 2). In both experiments, children demonstrated skepticism toward testimony from previously inconsistent sources. Executive function and working memory each predicted inconsistency detection. These findings indicate logical inconsistency understanding emerges in early childhood, is supported by social and domain general cognitive skills, and plays a role in adaptive learning from testimony.

A meta-analysis of the Dimensional Change Card Sort: Implications for developmental theories and the measurement of executive function in children.

The Dimensional Change Card Sort (DCCS) is a widely used measure of executive function in children. In the standard version, children are shown cards depicting objects that vary on two dimensions (e.g., colored shapes such as red rabbits and blue boats), and are told to sort them first by one set of rules (e.g., shape) and then by another (e.g., color). Most 3-year-olds persist in sorting by the pre-switch rules, whereas 5-year-olds switch flexibly. We conducted a meta-analysis of standard and experimental versions of the task (N = 69 reports, 426 conditions) to examine the influence of diverse task variations on performance. Age, how the test stimuli were labeled for the child, emphasis on conflict in the verbal introduction of the post-switch rules, and the number of pre-switch trials each independently predicted switching on the standard DCCS, whereas pre-switch feedback, practice, and task modality did not. Increasing the relative salience of the post-switch dimension was associated with higher rates of switching, and, conversely, decreasing post-switch salience was associated with lower rates of switching, and under both kinds of manipulation performance continued to be associated with age. Spatially separating the dimensional values was associated with higher rates of switching, and it was confirmed that the degree of spatial separation matters, with children benefiting most when the dimensional values are fully spatially segregated. Switch rates tended to be higher in versions on which children were prompted to label the stimuli compared to when the experimenter provided labels, and lower when reversal instructions were used in conjunction with the standard task stimuli. Theoretical and practical implications for the study and measurement of executive function in early childhood are discussed.

Children's use of moral behavior in selective trust: discrimination versus learning.

Does valence play a role in children's sensitivity to and use of moral information in the service of selective learning? In the present experiment, we explored this question by presenting 3- to 5-year-old children with informants who behaved in ways consistent or inconsistent with sociomoral norms, such as helping a peer retrieve a toy or deliberately tearing a peer's artwork. "Good" versus "bad" informants were contrasted with putatively neutral-behaving informants. In an effort to specify the role that moral information plays in guiding children's selective trust, we measured children's ability to discriminate the informants as well as their willingness to learn from them. We found that children were significantly more likely to discriminate negatively behaving agents from neutral ones than they were to discriminate positively behaving agents from neutral ones. In contrast, children did not differ in the degree to which they used negative versus positive moral information in their selective learning; both types of information were used to guide trust across domains of knowledge. Results are discussed in terms of the positive-negative asymmetry observed and the different forms that a negativity bias might take.

Bottom-up and top-down dynamics in young children's executive function: Labels aid 3-year-olds' performance on the Dimensional Change Card Sort.

Executive function (EF) improves between the ages of 3 and 5 and has been assessed reliably using the Dimensional Change Card Sort (DCCS), a task in which children first sort bivalent cards by one dimension (e.g., shape) and then are instructed to sort by a different dimension (e.g., color). Three-year-olds typically perseverate on the pre-switch dimension, whereas 5-year-olds switch flexibly. Labeling task stimuli can facilitate EF performance (Jacques & Zelazo, 2005; Kirkham, Cruess, & Diamond, 2003), but the nature of this effect is unclear. In 3 experiments we examined 2 hypotheses deriving from different theoretical perspectives: first, that labels facilitate performance in a more bottom-up fashion, by biasing attention to relevant task rules (Kirkham et al., 2003); and second, that labels aid performance in a more top-down fashion by prompting reflection and an understanding of the hierarchical nature of the task (Zelazo, 2004). Children performed better on the DCCS when labels referred to the relevant sorting dimension (Experiment 1). This was a function of the content of the labels rather than the change in auditory signal across phases (Experiment 2). Furthermore, labeling the opposite dimension only did not have a symmetrically negative effect on performance (Experiment 3). Together, these results suggest external, verbal labels bias children to attend to task-relevant information, likely through interaction with emerging top-down, endogenous control.

Association of folate receptor (FOLR1, FOLR2, FOLR3) and reduced folate carrier (SLC19A1) genes with meningomyelocele.

BACKGROUND: Meningomyelocele (MM) results from lack of closure of the neural tube during embryologic development. Periconceptional folic acid supplementation is a modifier of MM risk in humans, leading toan interest in the folate transport genes as potential candidates for association to MM. METHODS: This study used the SNPlex Genotyping (ABI, Foster City, CA) platform to genotype 20 single polymorphic variants across the folate receptor genes (FOLR1, FOLR2, FOLR3) and the folate carrier gene (SLC19A1) to assess their association to MM. The study population included 329 trio and 281 duo families. Only cases with MM were included. Genetic association was assessed using the transmission disequilibrium test in PLINK. RESULTS: A variant in the FOLR2 gene (rs13908), three linked variants in the FOLR3 gene (rs7925545, rs7926875, rs7926987), and two variants in the SLC19A1 gene (rs1888530 and rs3788200) were statistically significant for association to MM in our population. CONCLUSION: This study involved the analyses of selected single nucleotide polymorphisms across the folate receptor genes and the folate carrier gene in a large population sample. It provided evidence that the rare alleles of specific single nucleotide polymorphisms within these genes appear to be statistically significant for association to MM in the patient population that was tested.

Characteristics of a spina bifida population including North American Caucasian and Hispanic individuals.

BACKGROUND: Meningomyelocele (MM) is a common human birth defect. MM is a disorder of neural development caused by contributions from genes and environmental factors that result in the NTD and lead to a spectrum of physical and neurocognitive phenotypes. METHODS: A multidisciplinary approach has been taken to develop a comprehensive understanding of MM through collaborative efforts from investigators specializing in genetics, development, brain imaging, and neurocognitive outcome. Patients have been recruited from five different sites: Houston and the Texas-Mexico border area; Toronto, Canada; Los Angeles, California; and Lexington, Kentucky. Genetic risk factors for MM have been assessed by genotyping and association testing using the transmission disequilibrium test. RESULTS: A total of 509 affected child/parent trios and 309 affected child/parent duos have been enrolled to date for genetic association studies. Subsets of the patients have also been enrolled for studies assessing development, brain imaging, and neurocognitive outcomes. The study recruited two major ethnic groups, with 45.9% Hispanics of Mexican descent and 36.2% North American Caucasians of European descent. The remaining patients are African-American, South and Central American, Native American, and Asian. Studies of this group of patients have already discovered distinct corpus callosum morphology and neurocognitive deficits that associate with MM. We have identified maternal MTHFR 667T allele as a risk factor for MM. In addition, we also found that several genes for glucose transport and metabolism are potential risk factors for MM. CONCLUSIONS: The enrolled patient population provides a valuable resource for elucidating the disease characteristics and mechanisms for MM development.