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8.
Maturitas ; 3(2): 135-44, 1981 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-6270507

RESUMO

The effects on blood-clotting factors, plasma lipids and endometrial proliferation of two types of oral oestrogen therapy (a) cyclical therapy with 0.625 mg/day conjugated equine oestrogens for 3 wk followed by 1 wk without treatment, and (b) continuous therapy with 2 mg/day oestriol) were investigated in a 5-mth study involving 22 post-menopausal women. Assays were performed in order to measure blood-clotting factors (activity of the factor II-VII-X complex, anti-thrombin III, euglobulin lysis time) and plasma lipids (total cholesterol, triglycerides, lipoprotein electrophoresis) before treatment and after 3 and 4 mth of treatment. The only significant change found to have occurred was a decrease in the beta: alpha lipoproteins ratio; this was greater in the group treated with conjugated equine oestrogens, but was also statistically significant in the group treated with oestriol. Endometrial proliferation was investigated indirectly by means of the medroxyprogesterone acetate (MPA) test before treatment and after 5 mth of treatment. The response to MPA at the end of 5 mth of treatment in patients previously unresponsive, showed endometrial proliferation to have occurred during treatment with conjugated equine oestrogens but not during treatment with oestriol.


Assuntos
Coagulação Sanguínea/efeitos dos fármacos , Endométrio/efeitos dos fármacos , Estriol/farmacologia , Lipídeos/sangue , Menopausa/efeitos dos fármacos , Fatores de Coagulação Sanguínea/análise , Colesterol/sangue , Ensaios Clínicos como Assunto , Estrogênios Conjugados (USP) , Feminino , Hormônio Foliculoestimulante/sangue , Humanos , Lipoproteínas/sangue , Pessoa de Meia-Idade , Distribuição Aleatória , Triglicerídeos/sangue
16.
Minerva Med ; 70(49): 3365-8, 1979 Nov 10.
Artigo em Italiano | MEDLINE | ID: mdl-503353

RESUMO

The influence of various maternal and neonatal factors on blood bilirubin is examined. An increase in neonatal values may be due to the relatively advanced age of the mother, whereas neonatal age, sex and weight, increase in maternal weight during pregnancy, and maternal body surface area would appear to be without influence.


Assuntos
Bilirrubina/sangue , Peso ao Nascer , Antígenos de Grupos Sanguíneos , Superfície Corporal , Peso Corporal , Feminino , Humanos , Recém-Nascido , Idade Materna , Gravidez , Fatores Sexuais
17.
Minerva Med ; 70(49): 3349-55, 1979 Nov 10.
Artigo em Italiano | MEDLINE | ID: mdl-228220

RESUMO

A case of trophoblastic disease in a twin pregnancy is described from its diagnosis to follow-up after emptying of the uterine cavity. The possible causes of trophoblastic disease are discussed.


Assuntos
Neoplasias Trofoblásticas/patologia , Adulto , Edema/tratamento farmacológico , Feminino , Feto , Furosemida/uso terapêutico , Humanos , Hipotireoidismo/diagnóstico , Placenta/patologia , Gravidez , Tireoglobulina/uso terapêutico , Gêmeos , Útero/patologia
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