RESUMO
The routing of patients plays a key role in early detection of oncologic diseases. The clear conception of this technique still is not adequately formed in many regions. In Tchelyabinsk oblast the developed scheme of routing of patients in case of suspicion on malignant neoplasm is an integral part of organizational complex of preventive activities. From 2005, this approach resulted in the increase of detection rate of tumors of I-II stages and in the decrease of indicators of identified primary neglected processes one-year and lethality.
Assuntos
Neoplasias/diagnóstico , Neoplasias/terapia , Lesões Pré-Cancerosas/diagnóstico , Lesões Pré-Cancerosas/terapia , Detecção Precoce de Câncer , Feminino , Humanos , Masculino , Federação Russa/epidemiologiaRESUMO
The data on combined photon-neutron radiation therapy of brain tumors (23 patients) are presented. Total focal dose (NSD) of photon radiation was 48-60 isoGy; neutron radiation--2.4 Gy (OBE equivalent to gamma radiation of 14.4 Gy). Out of 23 patients, 15 (65.2%) had suffered from tumor disease for a long time which continued after surgery or combined treatment, while 8 (34.8%) were followed up after treatment for primary brain tumor. First symptoms were evaluated. Dehydration therapy was given to 16 (69.6%). Photon- neutron radiation therapy follow-up was up 12 months. Immediate results were assessed every week. The number of complaints went down by approximately 12-15%; improvement was reported in 13 (56.5%), stabilization--9 (39.2%), deterioration--1 (4.8%). According to CT examination of the brain one month later, condition at focal site was unchanged in 17 (73.9%), 10% regression of tumor--6(26.1%). General aggravation of symptoms without roentgenological signs of tumor progression was registered in one case 3 months later. Brain tumor relapsed in still another patient 4 months later. All patients survived 12 months. These indices were 1.5-2 times higher than those for treatment of similar pathology using photon component alone.