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Skin Res Technol ; 14(1): 45-52, 2008 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-18211601

RESUMO

BACKGROUND/PURPOSE: The efficacy of cosmetics on human skin measured under normal mild laboratory environment might be discounted by exterior environment factors such as wind, UV exposure, etc. Few studies have focused on the 'genuine' efficacy of cosmetics on human skin during exposure to external rigorous environment. The aim of this study was to develop a model for the evaluation of the efficacy of cosmetics on human skin under simulated rigorous environment. METHODS: We measured skin water content and transepidermal water loss (TEWL) before and after products application under simulated windy and sub-erythema UV exposure treatment in a constant temperature and humidity laboratory. RESULTS: The results showed that the products had higher water content and lower TEWL at 2, 4 and 8 h of products application, and ameliorated the skin moisturization situation after a 3-week continuous use of the products. In addition, the products might protect the skin to maintain the normal water content and TEWL under the simulated windy or sub-erythema UV exposure treatment in our laboratory when compared with untreated area. CONCLUSION: Our data indicate that this model may provide a more accurate evaluation for the genuine moisturizing effect of cosmetics under external natural climate.


Assuntos
Cosméticos/farmacologia , Emolientes/farmacologia , Fenômenos Fisiológicos da Pele , Pele/efeitos dos fármacos , Adulto , Bochecha/fisiologia , Cosméticos/farmacocinética , Capacitância Elétrica , Emolientes/farmacocinética , Ambiente Controlado , Feminino , Antebraço/fisiologia , Humanos , Pele/efeitos da radiação , Raios Ultravioleta , Perda Insensível de Água , Vento
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