Assuntos
Decápodes/efeitos dos fármacos , Atividade Motora/efeitos dos fármacos , Compostos Policíclicos/farmacologia , Tetrodotoxina/farmacologia , Toxinas Biológicas/farmacologia , Animais , Antitoxinas , Técnicas In Vitro , Larva/efeitos dos fármacos , Compostos Policíclicos/antagonistas & inibidores , Compostos Policíclicos/toxicidade , Relação Estrutura-Atividade , Fatores de Tempo , Toxinas Biológicas/toxicidadeRESUMO
The mass spectra of grayanotoxin III and some of its mono-, di, and tri-ester derivatives are discussed. Some of the physiological responses of this compound class are also presented. The extraction of this material from a natural source is discussed as well as the schemes for ester derivatization and spectral characterization of all compounds studied. High resolution mass spectral analysis and comparison of the mass spectra of similar compounds were used to define possible fragmentation mechanisms.
Assuntos
Plantas Tóxicas/análise , Toxinas Biológicas/análise , Diterpenos/análise , Espectrometria de MassasAssuntos
Antibacterianos , Benzofenonas , Fenômenos Químicos , Química , Cristalização , Conformação Molecular , PlantasRESUMO
A phytochemical investigation of the acidic fraction from an ethanolic extract of the roots of Ruscus aculeatus L. (Liliaceae) has resulted in the isolation and identification of a sterol mixture, a fatty acid mixture, chrysophanic acid, a new compound named euparone and an incompletely characterized phenolic substance.