1.
Kidney Int
; 102(2): 449, 2022 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35870820
2.
Antivir Ther
; 22(4): 357-359, 2017.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27879484
RESUMO
It is unclear whether immunosuppression is a risk factor for herpes encephalitis. Herein, we describe a rare case of herpes simplex virus type 2 encephalitis in a patient treated with low-dose methotrexate for HLA-B27-associated spondyloarthritis. The patient was successfully treated with acyclovir but presented sequelae of encephalitis. Here we discuss the possible role of low-dose methotrexate therapy as a risk factor of neurological herpes reactivation and severe disease. The host-related and viral risk factors are also addressed.