[Condition of the human skin during a stay in a hermetically closed compartment]. / Sostoianie kozhi cheloveka vo vremia prebyvaniia v germetichno-zamknutom pomeshchenii.

The skin of healthy men kept in an enclosed environment was examined. It was found that exposure resulted in increases of the secretions of the sebaceous glands and sebum cutaneum, number and size of comedones, lipolytic activity of microorganisms, concentration of comedonogenic acids and skin irritating acids. It also caused a greater risk of papular and pustular rashes. Changes in lipid metabolism were consistent with the skin clinical state as well as with the subjective sensations of dirty skin, desquamation and itching. The severity of the above changes was correlated with the pretest physiological and hygienic status of the subjects.

[Evaluation of human skin function in a sealed room by a chromatographic method]. / Otsenka sostoianiia kozhi cheloveka v germopomeshchenii s pomoshch'iu khromatograficheskogo metoda.

Gas-liquid chromatogrophy was used to study the skin and sebum cutaneum of 6 male test subjects (aged 45-55) before and after 30-day enclosure. The greatest changes were seen in the composition of free fatty acids of lipids of the facial skin (increase of palmito-oleic acid). The lipid composition of the sebum cutaneum of the healthy subjects differed from that of the acne-bearing subjects. It is recommended to use the ratio of palmitic acid to palmito-oleic acid as a measure of changes of fatty acids in the sebum cutaneum of healthy people in an unusual environment.