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1.
PLoS One ; 7(2): e31064, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22363547

RESUMO

We present a rectangle-based segmentation algorithm that sets up a graph and performs a graph cut to separate an object from the background. However, graph-based algorithms distribute the graph's nodes uniformly and equidistantly on the image. Then, a smoothness term is added to force the cut to prefer a particular shape. This strategy does not allow the cut to prefer a certain structure, especially when areas of the object are indistinguishable from the background. We solve this problem by referring to a rectangle shape of the object when sampling the graph nodes, i.e., the nodes are distributed non-uniformly and non-equidistantly on the image. This strategy can be useful, when areas of the object are indistinguishable from the background. For evaluation, we focus on vertebrae images from Magnetic Resonance Imaging (MRI) datasets to support the time consuming manual slice-by-slice segmentation performed by physicians. The ground truth of the vertebrae boundaries were manually extracted by two clinical experts (neurological surgeons) with several years of experience in spine surgery and afterwards compared with the automatic segmentation results of the proposed scheme yielding an average Dice Similarity Coefficient (DSC) of 90.97±2.2%.


Assuntos
Algoritmos , Processamento de Imagem Assistida por Computador/métodos , Automação , Glioblastoma/patologia , Humanos , Imageamento Tridimensional , Imageamento por Ressonância Magnética , Coluna Vertebral/patologia
2.
J Craniomaxillofac Surg ; 40(5): 396-9, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21862340

RESUMO

Dislocation of the mandibular condyle into the middle cranial fossa is a rare complication of mandibular trauma due to anatomical and biomechanical factors. Owing to the proximity of the temporal glenoid fossa to the middle meningeal artery, there is the risk of serious sequelae in case of trauma. The authors report the case of a 36-year-old male patient, who was beaten up in a family dispute and presented with complex mandibular and maxillofacial fractures, including mandibular condyle intrusion into the middle cranial fossa causing extensive meningeal bleeding. The patient underwent immediate surgery, with evacuation of the epidural haematoma via a temporal approach. In addition open reduction and reconstruction of the temporal glenoid fossa via anatomic reduction of the fragments was performed. A functional occlusion was re-established via miniplate reconstruction of the complex mandibular body and ramus fractures. Prompt diagnosis and a multidisciplinary approach are essential to minimize the complications. Advanced imaging modalities of computed tomography are indicated. Treatment options should be individualized in particular in case of suspected neurological injury.


Assuntos
Fossa Craniana Média/lesões , Hematoma Epidural Craniano/etiologia , Luxações Articulares/complicações , Côndilo Mandibular/lesões , Fraturas Mandibulares/complicações , Adulto , Placas Ósseas , Ossos Faciais/lesões , Seguimentos , Fixação Interna de Fraturas/instrumentação , Hematoma Epidural Craniano/cirurgia , Humanos , Imageamento Tridimensional/métodos , Luxações Articulares/cirurgia , Masculino , Côndilo Mandibular/cirurgia , Fraturas Mandibulares/cirurgia , Artérias Meníngeas/lesões , Procedimentos de Cirurgia Plástica/métodos , Fraturas Cranianas/complicações , Osso Temporal/lesões , Osso Temporal/cirurgia , Articulação Temporomandibular/lesões , Articulação Temporomandibular/cirurgia , Tomografia Computadorizada por Raios X/métodos , Violência
3.
Neurosurgery ; 69(3): 689-95, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21508880

RESUMO

BACKGROUND: Symptomatic patients with a brainstem cavernoma are treated surgically with increasing frequency. Generally, the patient's benefit from this difficult surgical intervention is quantified by the assessment of neurological symptoms. OBJECTIVE: To document the beneficial effect of surgery in a larger patient population by assessing the postoperative quality of life (QoL). METHODS: In a series of 71 surgically treated patients, a detailed neurological status was assessed by Patzold Rating and Karnofsky Performance Status Scale. Patients rated their QoL with the Short Form 36 Health Survey. To document the effect of surgery on QoL, we devised a supplementary questionnaire. The last 24 patients completed Short Form 36 Health Survey pre- and postoperatively. RESULTS: Karnofsky Performance Status Scale improved in 44 of 71 surgical patients (62%), remained unchanged in 19 (27%), and deteriorated in 8 (11%) individuals. Patzold Rating showed a more detailed picture of the neurological symptoms. It correlated significantly with Karnofsky Performance Status Scale, which underscores its usefulness for patients with brainstem lesions. In the Short Form 36 Health Survey score, the Mental Component Summary improved with surgery (paired test, P = .015). In addition, 58 individuals (82%) declared a clear subjective benefit of surgery. CONCLUSION: The results of this large series support the notion that microsurgical removal of a brainstem cavernoma represents an effective therapy in experienced hands and is generally associated with good clinical outcome, both neurologically and in terms of QoL.


Assuntos
Tronco Encefálico/cirurgia , Hemangioma Cavernoso/psicologia , Hemangioma Cavernoso/cirurgia , Qualidade de Vida , Adolescente , Adulto , Idoso , Hemorragia Cerebral/etiologia , Criança , Transtornos Neurológicos da Marcha/etiologia , Humanos , Imageamento por Ressonância Magnética , Masculino , Microcirurgia , Pessoa de Meia-Idade , Exame Neurológico , Testes Neuropsicológicos , Procedimentos Neurocirúrgicos , Complicações Pós-Operatórias , Período Pós-Operatório , Resultado do Tratamento , Adulto Jovem
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