Assuntos
Actinomicose/diagnóstico , Broncopneumonia/diagnóstico , Abscesso Pulmonar/diagnóstico , Actinomicose/cirurgia , Broncopneumonia/microbiologia , Broncopneumonia/cirurgia , Diagnóstico Diferencial , Humanos , Abscesso Pulmonar/microbiologia , Abscesso Pulmonar/cirurgia , Neoplasias Pulmonares/diagnóstico , Masculino , Pessoa de Meia-IdadeRESUMO
Malignant mesothelioma is a relatively uncommon malignancy. Although the pathogenesis is primarily related to asbestos, the role of ionizing radiation is more controversial. We report the case of a 41-year-old male who developed pleural mesothelioma. He had both, a prior short asbestos exposure and a thoracic radiotherapy for Hodgkin's disease 26years before. The evidence for radiotherapy as cause for mesothelioma is expanding and the diagnosis of mesothelioma in patients who had previous irradiation should be kept in mind.
Assuntos
Doença de Hodgkin/radioterapia , Neoplasias Pulmonares/diagnóstico , Mesotelioma/diagnóstico , Neoplasias Induzidas por Radiação/diagnóstico , Neoplasias Pleurais/diagnóstico , Adulto , Humanos , Neoplasias Pulmonares/etiologia , Masculino , Mesotelioma/etiologia , Mesotelioma Maligno , Neoplasias Pleurais/etiologia , Pleurisia/etiologia , Radiografia TorácicaRESUMO
Acquired eosinophilia is currently classified into secondary (reactional to underlying diseases), clonal (presence of a bone marrow histological, cytogenetic or molecular marker of a myeloid malignancy) and idiopathic (neither secondary nor clonal) categories. We report the case of a 47-year-old male who was admitted to the hospital for Staphylococcus aureus recurring infections. An hypereosinophilia was discovered and led to molecular analysis. The identification of FIP1L1-PDGFRA fusion gene permitted the diagnostic of clonal eosinophilia. Treatment by imatinib mesylate induced an haematological remission, the control of the infection and thoracotomy cicatrization. This case is original because of its infectious presentation and the efficacy of imatinib mesylate to control the infectious process.