RESUMO
Cathepsin H was secreted into the blood plasma of cancer patients before and after surgery. In the mandibular osteoradionecrosis group, there was a tendency for cathepsin H level to decrease, although only in cases free from recurrent tumor growth. Constant levels of cathepsin H were maintained after specific treatment, even in tumor recurrence-free cases. Secretion of such enzymes may be considered a characteristic of tumor-bearing organism. Biochemical assay of cathepsin H level may be used as another procedure for diagnosing different patterns of malignant growth.
Assuntos
Biomarcadores Tumorais/sangue , Catepsinas/sangue , Cisteína Endopeptidases , Neoplasias/sangue , Animais , Catepsina H , Feminino , Humanos , Masculino , Camundongos , Neoplasias Experimentais/sangue , Gravidez , Complicações Neoplásicas na Gravidez/sangue , RatosAssuntos
Neoplasias Faciais/terapia , Neoplasias Maxilomandibulares/terapia , Psicoterapia , Neoplasias Faciais/complicações , Neoplasias Faciais/psicologia , Humanos , Neoplasias Maxilomandibulares/complicações , Neoplasias Maxilomandibulares/psicologia , Transtornos Mentais/etiologia , Transtornos Mentais/prevenção & controle , Psicopatologia , Transtornos Psicofisiológicos/etiologia , Transtornos Psicofisiológicos/prevenção & controleRESUMO
The results of postoperative treatment of 102 cases operated upon for malignant neoplasms of the maxillofacial region are set forth. In 58 among them some concommitant diseases were observed involving mostly the cardiovascular system. During the operation, however, no complications in all the patients were noted except for the development of hypotension in time of anesthetizing in one case. Prophylaxis and treatment were performed depending on the phase of the postoperative period.
Assuntos
Neoplasias Mandibulares/cirurgia , Neoplasias Maxilares/cirurgia , Neoplasias Bucais/cirurgia , Idoso , Feminino , Seguimentos , Humanos , Neoplasias Labiais/cirurgia , Masculino , Pessoa de Meia-Idade , Metástase Neoplásica , Neoplasias das Glândulas Salivares/cirurgia , Neoplasias da Língua/cirurgiaAssuntos
Celulite (Flegmão)/cirurgia , Doenças Maxilares/complicações , Osteomielite/complicações , Adolescente , Adulto , Idoso , Antibacterianos/uso terapêutico , Celulite (Flegmão)/etiologia , Dermatoses Faciais/etiologia , Dermatoses Faciais/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Cuidados Pós-OperatóriosRESUMO
The results of treatment in 67 patients with associated injuries of the face and other regions of the body are analysed. Sixteen of them died. Their poor state was conditioned not by facial injuries but by traumas of other organs and system of the organism. It is concluded that such patients should be treated not in stomatological but in special traumatological departments for polytraumas. Surgery is first to be performed in the region where the damage is most hazardous. But the first step is to prevent aspiration of blood from the oral cavity into the respiratory tract followed by the fixation of jaw fragments.