RESUMO
The up-to-date possibilities of transfusion therapy are presented in the article. The authors analyzed their own experience and made a review of literature. The study considers the mechanisms of treatment, immunological and infectious risks, indications and contraindications for application of transfusion therapy in surgical practice.
Assuntos
Substitutos Sanguíneos , Transfusão de Sangue , Cirurgia Geral/métodos , Substitutos Sanguíneos/classificação , Substitutos Sanguíneos/farmacologia , Transfusão de Sangue/métodos , Procedimentos Médicos e Cirúrgicos sem Sangue , Contraindicações , Humanos , Avaliação de Resultados em Cuidados de Saúde , Medição de Risco , Reação TransfusionalRESUMO
On the ground of analysis of clinical experience and review of literature, the author is considering the problems of etiology, pathogenesis, clinic, diagnostics and treatment of disseminated intravascular clotting syndrome in surgical practice.
Assuntos
Coagulação Sanguínea , Diagnóstico por Imagem/métodos , Coagulação Intravascular Disseminada , Coagulação Intravascular Disseminada/sangue , Coagulação Intravascular Disseminada/diagnóstico , Coagulação Intravascular Disseminada/cirurgia , Humanos , Complicações Pós-Operatórias , Fatores de RiscoRESUMO
On the basis of literature data and personal clinical experience the author gives clinical interpretation of hemostasiogram tests used in clinical practice and an algorithm of the clinical analysis of the hemostasiogram allowing detection of concrete disorders in the hemostasis mechanisms and decision on the pathogenetically substantiated program of therapy for bleedings in surgical practice.
Assuntos
Algoritmos , Testes de Coagulação Sanguínea/normas , Coagulação Sanguínea , Perda Sanguínea Cirúrgica/prevenção & controle , Hemorragia Pós-Operatória/prevenção & controle , Humanos , Hemorragia Pós-Operatória/sangueRESUMO
On the basis of clinical experience the author substantiates the algorithm of clinico-laboratory emergency diagnostics and differential diagnostics of acute bleedings caused by disturbances of the primary and secondary hemostasis.
Assuntos
Algoritmos , Técnicas de Diagnóstico do Sistema Digestório , Emergências , Hemorragia Gastrointestinal/diagnóstico , Transtornos Hemostáticos/complicações , Doença Aguda , Hemorragia Gastrointestinal/etiologia , HumanosRESUMO
In the paper the authors are making an analysis of the courses of hemotransfusion complications and recommend a system of measures to prevent them.
Assuntos
Incompatibilidade de Grupos Sanguíneos/prevenção & controle , Transfusão de Sangue/métodos , Incompatibilidade de Grupos Sanguíneos/epidemiologia , HumanosRESUMO
The authors made an analysis of results of examination of 41 patients with ischemic heart disease treated by the standard medicamentous therapy and when using different methods of photohemotherapy against its background. It was established that medicamentous therapy during 2 weeks failed to result in a substantial improvement of rheological properties of blood, while its combination with photohemotherapy could give a considerable positive effect coinciding with clinical improvement of the patient's state. Shorter terms are required to correct hemorheological indices when autotransfusions of photomodified blood are used.
Assuntos
Transfusão de Sangue Autóloga/métodos , Sangue/efeitos da radiação , Hemorreologia/efeitos da radiação , Isquemia Miocárdica/terapia , Terapia Ultravioleta/métodos , Idoso , Transfusão de Sangue Autóloga/instrumentação , Viscosidade Sanguínea/efeitos dos fármacos , Viscosidade Sanguínea/efeitos da radiação , Fármacos Cardiovasculares/uso terapêutico , Cateterismo Periférico , Terapia Combinada , Quimioterapia Combinada , Feminino , Hemorreologia/efeitos dos fármacos , Humanos , Masculino , Pessoa de Meia-Idade , Isquemia Miocárdica/sangue , Fatores de Tempo , Terapia Ultravioleta/instrumentaçãoRESUMO
The effectiveness of a suspension of erythrocytes in the new colloid preservative "Modegel" (in 1:1 ratio) was studied in the complex treatment of 31 patients with severe gastroduodenal bleedings. It was established that the hemodynamic, antianemic action of the suspension was not inferior (and even excels) to the action of the whole preserved blood and the erythrocytic mass. The suspension transfusion has a favorable effect upon functions of the liver and kidneys, corrects the acidic-alkaline state of the recipients' blood, decreases the lipid peroxidation and has detoxicating properties. During transfusion of the suspension hypocoagulation of blood doesn't take place. The temperature reactions following the suspension transfusion are rare. The suspension of erythrocytes "Modegel" deserves wide introduction to clinical practice.
Assuntos
Transfusão de Eritrócitos/métodos , Hemorragia Gastrointestinal/terapia , Doença Aguda , Adolescente , Adulto , Idoso , Preservação de Sangue , Estudos de Avaliação como Assunto , Feminino , Hemorragia Gastrointestinal/sangue , Hemorragia Gastrointestinal/fisiopatologia , Gelatina , Géis , Hemodinâmica , Humanos , Masculino , Pessoa de Meia-IdadeAssuntos
Transfusão de Sangue Autóloga/métodos , Sangue/efeitos da radiação , Procedimentos Cirúrgicos Operatórios , Terapia Ultravioleta/métodos , Adulto , Idoso , Transfusão de Sangue Autóloga/normas , Terapia Combinada , Relação Dose-Resposta à Radiação , Feminino , Homeostase/efeitos da radiação , Humanos , Medições Luminescentes , Masculino , Pessoa de Meia-Idade , Terapia Ultravioleta/normasRESUMO
Under study was the influence of different regimens of blood photomodification on the course of the tumor process. Experiments were carried out on 460 syngeneic mice with a model of Lewis adenocarcinoma of lungs and melanoma B 16. It was established that the influence of APMB on the course of the tumor process is dose-dependent and when specially selected the regimen of APMB may have an antitumoral effect. The transfusion of the photomodified donor blood may facilitate the suppression of antitumoral immune reaction of the recipient organism.