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Sci Rep ; 14(1): 12883, 2024 06 05.
Artigo em Inglês | MEDLINE | ID: mdl-38839874

RESUMO

Exhaust emissions, which count among the most common causes of premature death worldwide, can cause irreversible changes in cells, leading to their damage or degeneration. In this research, L929 line cells were observed after exposure in the BAT-CELL chamber to exhaust gases emitted from a Euro 6 compression-ignition engine. Real road traffic conditions were simulated, taking into account air resistance while driving at speeds of 50 km/h, 120 km/h and idling engine. Morphological analysis of the cells was performed using an environmental scanning electron microscope. It has been observed that diesel exhaust fumes can cause inflammation, which can induce apoptosis or leads to necrotic cell death. The impact of the vehicle exhaust gases can inhibit cell proliferation by almost three times. Moreover, a correlation has been observed between the speed of the inflammatory reaction in cells and the presence of specific hydrocarbon compounds that determine the toxicity of exhaust gases. Research has shown that the toxicity of the emitted exhaust gases has been the highest at the driving speed of 120 km/h. In order to reduce the harmful effects of exhaust emissions, ecological alternatives and the supplementation of legal provisions regarding the compounds subject to limitation are necessary.


Assuntos
Sobrevivência Celular , Hidrocarbonetos , Emissões de Veículos , Emissões de Veículos/toxicidade , Emissões de Veículos/análise , Animais , Camundongos , Sobrevivência Celular/efeitos dos fármacos , Linhagem Celular , Hidrocarbonetos/toxicidade , Microscopia Eletrônica de Varredura , Poluentes Atmosféricos/toxicidade , Poluentes Atmosféricos/análise
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