Seroprevalence of anti-Toxoplasma gondii IgG antibody and risk factors among abattoir workers in Uyo, Southern Nigeria.

CONTEXT: The asymptomatic nature of toxoplasmosis with its severe consequences, especially in populations with high HIV infection rate, makes it a disease of public health importance. Being a zoonosis, Toxoplasma gondii infection may be high among people who work with animals. Thus, there is the need to determine the prevalence of the infection among abattoir workers in Uyo, where HIV prevalence rate is in double digits, which could lead to reactivation of toxoplasmosis in those with immunosuppression. AIM: To determine the prevalence and associated risk factors of T. gondii infection in abattoir workers in Uyo. SETTINGS AND DESIGN: A descriptive cross-sectional study that was conducted among persons who work with livestock and birds, in Uyo and its environs. METHODOLOGY: The study was conducted among 339 workers in abattoirs in Uyo and its environs. Data were collected using interviewer-administered questionnaire and detection of IgG antibodies to T. gondii using ELISA technique and HIV testing using the national algorithm. Data were analyzed using STATA statistical software version 20, and statistically significant level was set at P < 0.05. RESULTS: The seroprevalence of T. gondii IgG antibodies among the study participants was 55.8%. At a univariate level, many factors were associated with T. gondii seropositivity; they were age, sex, level of education, ethnicity, occupation in the abattoir, type of animal exposure, always washing hands before eating in the workplace, and taking of raw/unpasteurized milk. However, after multivariate analysis, participants exposed to poultry, butchers/raw meat sellers, and those who had worked for more than 5 years in abattoirs were at a greater risk of being T. gondii IgG seropositive; odds ratio (OR) 5.46 [confidence interval (CI) 1.88, 15.86]; OR 1.89 (CI 1.14, 3.14), and OR 1.25 (CI 1.25, 6.42), respectively. CONCLUSION: T. gondii IgG seroprevalence is high among abattoir workers in Uyo, and there is a need for Akwa Ibom State government to establish enlightenment and prevention programs for these occupationally exposed and other populations at risk of infection.

High blood pressure in a semi-urban community in south-south Nigeria: a community-based study.

BACKGROUND: Non communicable diseases (NCDs) are taking their toll in most low and middle income countries; incidentally, in the same populations that are struggling to deal with communicable diseases, hence presenting a picture of "double tragedy". Most of the researches conducted on NCDs are facility-based; often in urban locations. OBJECTIVE: To determine the prevalence of high BP in a semi-urban community in Nigeria. METHODS: It was a cross-sectional study, where all the adult residents of the community were enrolled. Data was collected using a multi-section questionnaire, including anthropometric measurements. Data entry and analysis was done using SPSS 17.0 for windows and STATA 10. RESULTS: The results showed that 47.0% of the study population had a raised BP ≥140/90mmHg. At a univariate level, age, sex, higher income, more people in the household, daily cigarette smoking, daily alcohol intake and BMI, showed increased risk for high BP. However, sleeping for at least 8 hours a day showed protective influence against raised BP among the participants. In the adjusted model, only age, sex and BMI remained statistically significant with Odds Ratio (OR) of 1.04 (95%CI; 1.00, 1.08), 0.45 (95%CI; 0.22, 0.90) and 1.08(95%CI; 1.03, 1.13) respectively. The model had an area under curve of 71.9%. CONCLUSION: It was concluded that there is a high prevalence of raised BP in this semi-urban community, thus the need for intervention and preventive services to curb the looming epidemic of hypertension in this community in particular, and Nigeria as a whole, cannot be overemphasized.

Motorcycle Road Traffic Injuries in Southern Nigeria: The Small Motorcycle as a Prevention Strategy

Background: The commonest mode of public transportation in Uyo is by motorcycle. There are two sizes of motorcycle in common use - the big one (Qlink or Skygo model; made in China) and the small one (C90; made in China). The study was carried out to determine if there is a lower risk of RTI severe enough to be brought to the hospital; attributable to using a small motorcycle. Methods: Motorcycle RTI victims admitted at the Accident and Emergency department of the University of Uyo Teaching Hospital (UUTH); were reviewed prospectively over a 15 month period. Three community visual surveys of the proportion of small to large motorcycles were also conducted. Results: A total of 131 RTI victims were reviewed over 15 months. The visual surveys of motorcycles in Uyo revealed that the mean proportion of small to large is 38 to 62; a ratio of 1:1.6. Eighty-three (63.3) of the 131 RTI's involved motorcycles. 74 of these occurred in large motorcycles. There was a statistically significant relationship between motorcycle size and occurrence of an RTI severe enough to be brought to hospital. Conclusion: There is a lower risk of RTI severe enough to be brought to hospital; from using a small motorcycle