RESUMO
OBJECTIVE: Chlamydophila pneumoniae is a common agent of respiratory infections. Severe acute neurological infections are very infrequently linked to this bacterium. We report such a case and give a rapid overview of published cases of acute encephalitis occurring after a respiratory infection due to C. pneumoniae. PATIENT AND METHODS: A 12-year-old child without any prior medical history was hospitalized for encephalitis associated to respiratory symptoms. RESULTS: C. pneumoniae DNA was identified by multiplex PCR assay in respiratory secretions and C. pneumoniae IgM and IgG antibodies were assessed in the serum. This bacterium was not detected in CSF, nor was any other pathogen. A macrolide treatment was prescribed for two weeks. The outcome was good without any sequels. CONCLUSIONS: This observation correlates to the few similar cases reported in the medical literature. C. pneumoniae must be suggested in the etiological diagnosis of acute encephalitis, notably in a context of respiratory infection, when no more common cause can be identified.
Assuntos
Pneumonia por Clamídia/complicações , Chlamydophila pneumoniae/isolamento & purificação , Encefalite/etiologia , Doença Aguda , Antibacterianos/uso terapêutico , Anticorpos Antibacterianos/sangue , Criança , Pneumonia por Clamídia/tratamento farmacológico , Pneumonia por Clamídia/microbiologia , Chlamydophila pneumoniae/imunologia , DNA Bacteriano/análise , Dor de Orelha/etiologia , Encefalite/líquido cefalorraquidiano , Encefalite/tratamento farmacológico , Hematúria/etiologia , Humanos , Imunoglobulina G/sangue , Imunoglobulina G/imunologia , Imunoglobulina M/sangue , Imunoglobulina M/imunologia , Josamicina/uso terapêutico , Masculino , Sinusite/etiologia , Vômito/etiologiaRESUMO
The aim of this study was to determine the susceptibility rates and patterns in P. aeruginosa strains isolated from 2002 to 2005 in a teaching Hospital of Tunisia. Susceptibility to antibiotics was assessed according to CA-SFM guidelines. During this period, 1368 strains of P. aeruginosa were identified, they were isolated mainly from pus (52.9%), respiratory samples (19.5 %), urine (10.6%), and blood cultures (5%). The percentages of resistant isolates were as follows: ticarcilline: 26.2%; ceftazidime: 21.8%; imipenem: 19.6%; gentamicin: 39.3%; amikacin: 19.2%, and ciprofloxacin: 21.6%. Nosocomial infections in P. aeruginosa are responsible for important morbidity and mortality rates, the survey of resistance to antibiotics is necessary for an efficient treatment.
