[A case of primary diagnosis of patent ductus arteriosus at the age of 75 years]. / Sluchai pervichnoi diagnostiki otkrytogo arterial'nogo protoka u patsientov v vozraste 75 let.

The paper describes a case of primary diagnosis of functioning patent ductus arteriosus in a 75-year-old female patient.

[The prolonged-action form of Lomir (isradipine) in the treatment of mild and moderate essential hypertension]. / Forma lomira (isradipina) prolongirovannogo deistviia pri lechenii miagkoi i umerennoi éssentsial'noi gipertonii.

24-hour monitoring of arterial pressure has been performed outpatiently in 20 subjects with mild or moderate essential hypertension using portable system Space Labs 90207. The design of the study implied 2 weeks of observation without any treatment followed by a 4-week course of lomir SRO-5 plus a 2-week course of lomir administration in a double dose. Control examination was performed at the end of each period. It was established that a 4-week lomir course results in a lowering of systolic and diastolic pressure by 8.4 + -2.1 and 6.9 + -1.3 mm Hg, respectively. Double-dose lomir was also effective: a fall in both systolic and diastolic pressure by 15.6 + -3.2 and 8.1 + -1.8 mm Hg, respectively, was achieved.

[Blood pressure variability (based on 24-hour monitoring data) in mild arterial hypertension]. / Variabel'nost' arterial'nogo davleniia (po dannym 24-chasovogo monitorirovaniia) pri miagkoi arterial'noi gipertonii.

To evaluate the condition of target organs in patients with mild arterial hypertension (MAH) under normal and high arterial pressure variability (APV), the authors examined 84 MAH males aged 40-60 and 14 matched healthy controls. At 24-h monitoring it was revealed that 32% of MAH patients had high variability of daytime and night arterial pressure which occurred more frequently in atherosclerotic lesion of extracranial carotid artery portions. MAH patients with high APV against those with normal APV develop carotid artery atherosclerosis 3.5 times more frequently, vascular disorders of the fundus of the eye stage II with angiosclerosis and thickening of the interventricular septum 2.5 and 1.8 times more frequently, respectively.