1.
Org Lett
; 11(12): 2579-81, 2009 Jun 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19514792
RESUMO
The tetracyclic indole alkaloid (-)-arboricine has been prepared using an asymmetric organocatalytic Pictet-Spengler reaction as the key step followed by a diastereoselective Pd-catalyzed iodoalkene/enolate cyclization. The absolute stereochemistry was unequivocally proven by X-ray crystallographic analysis and appeared to be opposite to the published structure in the original paper.