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1.
Pediatr Nephrol ; 2024 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-38358551

RESUMO

BACKGROUND: On February 6th, 2023, two consecutive earthquakes struck southeastern Türkiye with magnitudes of 7.7 and 7.6, respectively. This study aimed to analyze the clinical and laboratory findings, as well as management of pediatric victims with Crush Syndrome (CS) and Acute Kidney Injury (AKI). METHODS: The study included pediatric earthquake victims who were presented to Mersin University Hospital. Clinical and laboratory characteristics of the patients were collected retrospectively. RESULTS: Among 649 patients, Crush injury (CI), CS and AKI was observed in 157, 59, and 17 patients, respectively. White blood cell count (12,870 [IQR: 9910-18700] vs. 10,545 [IQR: 8355-14057] /µL, P < 0.001), C-reactive protein (51.27 [IQR: 14.80-88.78] vs. 4.59 [1.04-18.25] mg/L, P < 0.001) and myoglobin levels (443.00 [IQR: 198.5-1759.35] vs. 17 [11.8-30.43] ng/ml) were higher in patients with CS, while their sodium (IQR: 134 [131-137] vs. 136 [134-138] mEq/L, P < 0.001) levels were lower compared to non-CS patients. An increase in myoglobin levels was identified as an independent risk factor for developing CS (OR = 1.017 [1.006-1.027]). Intravenous fluid replacement was administered to the patients with CS at a dose of 4000 cc/m2/day. Hypokalemia was observed in 51.9% of the CS patients on the third day. All patients with AKI showed improvement and no deaths were reported. CONCLUSIONS: Hyponatremia and increase in inflammation markers associated with CS may be observed. An increase in myoglobin levels was identified as a risk factor for CS. Hypokalemia may be seen as a complication of vigorous fluid therapy during hospitalization.

2.
J Reprod Infant Psychol ; 42(1): 62-77, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-35345941

RESUMO

OBJECTIVE: This study was conducted to determine the prevalence of fear of childbirth and affecting factors in pregnant women in Turkey. MATERIALS AND METHODS: This was a cross-sectional study and included a total of 2025.    Pregnant Women Assessment, some variables related to previous and current perinatal processes and Wijma Delivery Expectancy/Experience Questionnaire (version A) were used for data collection. FINDINGS: In this sample, 42.4% of the women reported fear of childbirth. What the women were afraid of most was the development of unwanted conditions at childbirth, obscurity/uncertainty, and negative attitudes of health professionals. The factors causing fear of childbirth were the low education level, unemployment status, low financial status, stillbirth, unplanned pregnancy, indecisiveness about the type of delivery, not attending prenatal education programs, negative effects of other people, insufficient social support, confiding in the healthcare centre and health professional, negative, and indecisive birth perceptions, prior negative birth experiences and not feeling ready for childbirth (p < 0.001). CONCLUSIONS: The prevalence of fear of childbirth in this Turkish sample, especially in the multipara is higher than in Western countries. Causes of fear of childbirth can vary with countries and even with each region of a country.


Assuntos
Parto Obstétrico , Gestantes , Gravidez , Feminino , Humanos , Turquia , Prevalência , Estudos Transversais , Parto , Medo
3.
Acta Ortop Bras ; 31(spe1): e239997, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37082157

RESUMO

Objectives: This study was designed to investigate the possible relationship between the anatomical location of the PFF (head-neck fractures) and the demographic features, comorbidities, and risk factors of elderly patients. Methods: 233 patients aged 65 years and over, who were admitted to the emergency department with a diagnosis of proximal femur fracture were included in this study. Results: Most patients (59.6%) had a trochanteric fracture. The incidence of trochanteric fractures had a statistically significant positive correlation with age. Falls at ground level were found to be highly associated with trochanteric fractures (92,8%). At least one complication was observed in 57 (41,0%) cases and 31 (22,3%) died in one year, of the patients with trochanteric fractures. Comorbidity was not related to fracture location statistically. Fall ground level (p = 0.013), complication rate (73.7%; p <0.001), and Charlesen comorbidity index (p = 0.019) were statistically significantly associated with death. The logistic regression analysis of variables determined that only the quantity of comorbidities may be related to femoral neck fractures (p = 0.047). Conclusion: Female patients with trochanteric fractures were found to be older than male patients. Fall ground level, mortality, and complications were more frequently seen in patients with trochanteric fractures. Level of Evidence II, Retrospective study.


Objetivos: Este estudo foi desenhado para investigar a possível relação entre a localização anatômica da PFP (fraturas de cabeça e pescoço) e as características demográficas, comorbidades e fatores de risco de pacientes idosos. Métodos: Foram incluídos 233 pacientes com idade igual ou superior a 65 anos, admitidos no pronto-socorro com diagnóstico de fratura do fêmur proximal. Resultados: A maioria dos pacientes (59,6%) apresentou fratura trocantérica. A incidência de fraturas trocanterianas apresentou correlação positiva estatisticamente significativa com a idade. Verificou-se que as quedas no nível do solo estão altamente associadas às fraturas trocantéricas (92,8%). Pelo menos uma complicação foi observada em 57 (41%) casos e 31 (22,3%) morreram em um ano, dos pacientes com fraturas trocantéricas. A comoborbidade não foi realizada estatisticamente com a localização da fratura. Queda do nível do solo (p = 0,013), taxa de complicações (73,7%; p < 0,001), índice de comorbidade charlesen (p = 0,019) foram estatisticamente significativamente associados à morte. Na análise de regressão logística das variáveis, determinou-se que apenas a quantidade de comorbidades pode estar relacionada às fraturas do colo do fêmur (p = 0,047). Conclusão: Pacientes do sexo feminino com fraturas trocantéricas foram consideradas mais velhas do que pacientes do sexo masculino. Queda no nível do solo, mortalidade e complicações foram observadas com mais frequência em pacientes com fraturas trocantéricas. Nível de evidência II, Estudo retrospectivo .

4.
Ir J Med Sci ; 192(2): 861-870, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-35420366

RESUMO

BACKGROUND: This study was aimed at determining the risk factors associated with mortality in elderly patients with severe hyponatremia admitted to the emergency department. MATERIALS AND METHODS: The data of patients aged ≥ 65 years who were admitted to the emergency department and whose serum sodium levels were < 125 mEq/L were retrospectively collected. RESULTS: Mortality was associated with chronic liver disease/cirrhosis (p = 0.036), metastatic tumor (p = 0.007) and solid tumor (p = 0.013) cancers, antiarrhythmic drug use (p = 0.003), potassium-sparing diuretic use (p = 0.044), antineoplastic drug use (p = 0.0029), and dialysis treatment (p = 0.015). The following cutoff values were determined to be predictive of mortality: urea > 63.6 (AUC: 0.771; p = 0.0001), creatinine > 1.39 (AUC: 0.675; p = 0.0003), potassium > 4.64 (AUC: 0.711; p = 0.0001), C-reactive protein > 44 (AUC: 0.765; p = 0.0001), white blood cell count > 12.21 (AUC: 0.688; p = 0.0001), hemoglobin < 11.2 (AUC: 0.611; p = 0.0103), and Charlson comorbidity index > 2 (AUC: 0.739; p = 0.0001). The use of antineoplastic drugs (OR: 4.502; p = 0.010) and increased values of the following were associated with an increased risk of mortality: urea (OR: 1.007; p = 0.024), C-reactive protein (OR: 1.005; p = 0.026), glucose (OR: 1.008; p = 0.001), and Charlson comorbidity index (OR: 1.198; p = 0.025). CONCLUSION: Malignancy; liver cirrhosis; dialysis treatment; increased Charlson comorbidity index, urea, and C-reactive protein values and the use of antineoplastic drugs are associated with mortality.


Assuntos
Hiponatremia , Idoso , Humanos , Hiponatremia/etiologia , Hiponatremia/terapia , Estudos Retrospectivos , Proteína C-Reativa , Fatores de Risco , Cirrose Hepática , Serviço Hospitalar de Emergência , Ureia/uso terapêutico
5.
Acta ortop. bras ; 31(spe1): e239997, 2023. tab
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1429584

RESUMO

ABSTRACT Objectives: This study was designed to investigate the possible relationship between the anatomical location of the PFF (head-neck fractures) and the demographic features, comorbidities, and risk factors of elderly patients. Methods: 233 patients aged 65 years and over, who were admitted to the emergency department with a diagnosis of proximal femur fracture were included in this study. Results: Most patients (59.6%) had a trochanteric fracture. The incidence of trochanteric fractures had a statistically significant positive correlation with age. Falls at ground level were found to be highly associated with trochanteric fractures (92,8%). At least one complication was observed in 57 (41,0%) cases and 31 (22,3%) died in one year, of the patients with trochanteric fractures. Comorbidity was not related to fracture location statistically. Fall ground level (p = 0.013), complication rate (73.7%; p <0.001), and Charlesen comorbidity index (p = 0.019) were statistically significantly associated with death. The logistic regression analysis of variables determined that only the quantity of comorbidities may be related to femoral neck fractures (p = 0.047). Conclusion: Female patients with trochanteric fractures were found to be older than male patients. Fall ground level, mortality, and complications were more frequently seen in patients with trochanteric fractures. Level of Evidence II, Retrospective study.


RESUMO Objetivos: Este estudo foi desenhado para investigar a possível relação entre a localização anatômica da PFP (fraturas de cabeça e pescoço) e as características demográficas, comorbidades e fatores de risco de pacientes idosos. Métodos: Foram incluídos 233 pacientes com idade igual ou superior a 65 anos, admitidos no pronto-socorro com diagnóstico de fratura do fêmur proximal. Resultados: A maioria dos pacientes (59,6%) apresentou fratura trocantérica. A incidência de fraturas trocanterianas apresentou correlação positiva estatisticamente significativa com a idade. Verificou-se que as quedas no nível do solo estão altamente associadas às fraturas trocantéricas (92,8%). Pelo menos uma complicação foi observada em 57 (41%) casos e 31 (22,3%) morreram em um ano, dos pacientes com fraturas trocantéricas. A comoborbidade não foi realizada estatisticamente com a localização da fratura. Queda do nível do solo (p = 0,013), taxa de complicações (73,7%; p < 0,001), índice de comorbidade charlesen (p = 0,019) foram estatisticamente significativamente associados à morte. Na análise de regressão logística das variáveis, determinou-se que apenas a quantidade de comorbidades pode estar relacionada às fraturas do colo do fêmur (p = 0,047). Conclusão: Pacientes do sexo feminino com fraturas trocantéricas foram consideradas mais velhas do que pacientes do sexo masculino. Queda no nível do solo, mortalidade e complicações foram observadas com mais frequência em pacientes com fraturas trocantéricas. Nível de evidência II, Estudo retrospectivo.

6.
Natl Med J India ; 36(2): 76-82, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38692594

RESUMO

Background Patients visiting the emergency department (ED) may show variations by certain time periods such as Ramadan. We wished to ascertain whether Ramadan affects the ED presentations, clinical conditions and outcomes of patients aged 65 years or older. Methods . Patients aged 65 years or older who presented to ED in Ramadan and in the following month in 2018 were reviewed retrospectively. Results . A total of 1947 patients were enrolled, of whom 958 presented in Ramadan and 989 in the following month. The patients who presented in Ramadan most commonly (23.8%) presented between 8 p.m. and 11.59 p.m.; patients who presented in the following month most commonly (24%) presented between 8 a.m. and 11.59 a.m. (p=0.26). Complaints concerning the central nervous system (CNS) were more common in the month after Ramadan (p<0.0001). Diagnoses related to the cardiovascular system were more commonly made in Ramadan (p=0.037), whereas those related to CNS, otorhinolaryngology and oncology were more commonly made in the following month (p=0.0005, p=0.024 and p=0.003, respectively). No significant difference was found between the two groups with respect to outcomes (p=0.36). Compared to patients who presented in Ramadan, those that presented in the following month had a significantly longer ED stay (p=0.036). Conclusion . Our study detected no significant difference between the two groups with respect to the time of presentation and ED outcomes. Patients who presented in Ramadan had a lower incidence of CNS complaints; a higher incidence of cardiovascular diagnoses; lower incidences of CNS, oncological and otorhinolaryngological diagnoses and a significantly shorter length of ED stay.


Assuntos
Serviço Hospitalar de Emergência , Jejum , Islamismo , Humanos , Serviço Hospitalar de Emergência/estatística & dados numéricos , Feminino , Masculino , Idoso , Estudos Retrospectivos , Jejum/efeitos adversos , Idoso de 80 Anos ou mais , Índia/epidemiologia
7.
Clin Lab ; 68(12)2022 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-36546739

RESUMO

BACKGROUND: This study aimed to investigate the usefulness of platelet indices in predicting prognosis in coronavirus disease-19 (COVID-19). METHODS: Patients aged ≥ 65 years who presented to the emergency department with a positive polymerase chain reaction test were retrospectively analyzed. RESULTS: Significant differences were found in the mean values of platelet (PLT) and plateletcrit (PCT) parameters in those with severe disease, those who died, and those who required intensive care unit (ICU) admission. Mean PLT and PCT values were higher in patients with severe COVID-19 (p-values < 0.001, for both), those requiring ICU admission (p = 0.016; p = 0.006; respectively), and those who died (p = 0.015; p = 0.005, respectively). PLT and PCT were found to be statistically significant in predicting death [PLT (area under the curve (AUC): 0.598; p = 0.0145) and PCT (AUC: 0.617; p = 0.0034)], severity [PLT (AUC: 0.653; p = 0.0002) and PCT (AUC: 0.654; p = 0.0002)], and ICU admission [PLT (AUC: 0.598; p = 0.0235) and PCT (AUC: 0.605; p = 0.0148)]. CONCLUSIONS: PLT and PCT values were significantly higher in patients with high disease severity, those requiring ICU admission, and those who died. Furthermore, they were statistically significant in predicting disease severity, ICU admission, and death.


Assuntos
COVID-19 , Sepse , Idoso , Humanos , Estudos Retrospectivos , Plaquetas , Gravidade do Paciente , Prognóstico , Curva ROC
8.
Arch Psychiatr Nurs ; 41: 96-102, 2022 12.
Artigo em Inglês | MEDLINE | ID: mdl-36428081

RESUMO

PURPOSE: This research was conducted to determine the depression, anxiety, and stress levels of individuals during the COVID-19 epidemic. In addition, the compatibility of the Depression-Anxiety-Stress Scale (DASS-21) scale results with the participants' feeling depressed, anxious, and stressed were examined. DESIGN AND METHODS: The sample of the study consisted of 870 individuals over the age of 18 between May-August 2021. The data of the study were collected online, using the personal information form and DASS-21. RESULTS: In our study, it was observed that 22.3 % of the participants were severely depressed, 19.0 % were highly anxious and 14.3 % were highly stressed. In addition, a relationship was determined between many sociodemographic variables and depression, anxiety, and stress levels. It was found that individuals who were not vaccinated, did not receive health care, and were not satisfied with health care were more depressed, anxious, and stressed. The agreement between all DASS-21 sub-dimensions and participants' feeling is poor in terms of Cohen's kappa. The agreement is poor in the anxiety sub dimension, but moderate in the other sub-dimensions in terms of Gwet's AC1. PRACTICE IMPLICATIONS: It is recommended that nurses develop new care and evaluation strategies for the psychosocial field in order to protect and maintain the health of individuals during the COVID-19 pandemic process, as well as more practices promoting the COVID-19 vaccine in our country.


Assuntos
COVID-19 , Humanos , Adulto , Pessoa de Meia-Idade , COVID-19/epidemiologia , Depressão/psicologia , Vacinas contra COVID-19 , Turquia/epidemiologia , Pandemias , Estresse Psicológico/epidemiologia , Estresse Psicológico/psicologia , Ansiedade/psicologia
9.
Pediatr Int ; 64(1): e15055, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34773425

RESUMO

BACKGROUND: Renal scarring is a significant complication in recurrent urinary tract infections (UTIs) in children that can lead to hypertension and end-stage renal disease. The present study evaluates whether platelet indices may be predictive of renal scarring. METHODS: Sixty-nine patients aged 1-18 years with recurrent UTIs, whose medical records were reviewed to collect data on the presence of upper/lower UTIs and the results of scintigraphic investigations with 99m-technetium dimercaptosuccinic acid, were included in the study. The platelet, platelet indices (mean platelet volume [MPV]), platelet distribution width, plateletcrit, and C-reactive protein (CRP) values of the patients during UTI episodes were reviewed retrospectively. RESULTS: Mean platelet volume and CRP values were higher in the renal scarring group than in the non-renal scarring group (P < 0.001 and P = 0.003, respectively). Increases in MPV and CRP values were independent risk factors for renal scarring (OR = 5.781 [1.431-23.347] and OR = 1.922 [1.77-3.141], respectively). The sensitivity, specificity, positive and negative predictive values, and diagnostic odds ratio values of MPV at a cut-off of >8.2 fL for renal scarring discrimination were 62.5%, 88.89%, 75.00%, 81.63%, and 13.33 [1.35-3.83], respectively. The sensitivity, specificity, positive and negative predictive values, and diagnostic odds ratio values of CRP at a cut-off of 1.97 mg/L for renal scarring were 58.33%, 91.11%, 77.78%, 80.39%, and 14.35 [1.36-3.97], respectively. CONCLUSION: Both MPV and CRP can be used as predictive markers for renal scarring. While MPV had higher sensitivity, CRP had a higher specificity and diagnostic odds ratio in predicting renal scarring.


Assuntos
Cicatriz , Infecções Urinárias , Humanos , Criança , Estudos Retrospectivos , Cicatriz/diagnóstico , Cicatriz/etiologia , Infecções Urinárias/complicações , Proteína C-Reativa/metabolismo , Cintilografia
10.
Mikrobiyol Bul ; 55(4): 580-591, 2021 Oct.
Artigo em Turco | MEDLINE | ID: mdl-34666657

RESUMO

Invasive Candida infections are one of the most important risk factors for the increasing mortality of immunocompromised patients with comorbidities in intensive care units. In this study, it was aimed to evaluate the mortality rate and risk factors affecting mortality in patients followed up with the diagnosis of invasive candidiasis in our pediatric intensive care unit. Patients who were between the ages of 1 month and 18 years followed up in the paediatric intensive care unit with invasive candidiasis between 2014 and 2018, were included in the study. The demographic characteristics of the patients, fever and hypotension, the Candida species, use of broad-spectrum antibiotics, blood transfusion, parenteral nutrition, invasive interventions, use of mechanical ventilation and laboratory test results were retrospectively analyzed and the relationship with mortality was statistically determined. A total of 85 patients, 45 girls, and 40 boys were included in the study. The death rate was 38.8% (n= 33). Candida albicans (48%) was the most common species for all isolates followed by Candida parapsilosis (21%), Candida tropicalis (15%), and others (16%). No statistically significant relationship was detected between the central venous catheter, broad-spectrum antibiotic and corticosteroid treatment, parenteral nutrition, gender difference, surgical operation, patient culture samples, isolated Candida species, and mortality (p> 0.05). A statistically significant relationship was found between blood transfusion, thrombocytopenia, and leukopenia, the first positive culture time since hospitalization, and the duration of antibiotic treatment and mortality (p<0.05). A statistically significant correlation was found with the presence of hypotension, one of the clinical markers associated with mortality (p<0.05) but the same relationship was not found with the presence of fever (p> 0.05). The mortality rate is high in candidiasis patients in pediatric intensive care units. Blood transfusions, long-term use of broad-spectrum antibiotics, and hypotension increase mortality.


Assuntos
Candidíase Invasiva , Antifúngicos/uso terapêutico , Candida , Candidíase Invasiva/epidemiologia , Criança , Feminino , Humanos , Lactente , Unidades de Terapia Intensiva , Unidades de Terapia Intensiva Pediátrica , Masculino , Estudos Retrospectivos , Fatores de Risco
11.
Cardiovasc Toxicol ; 21(11): 927-935, 2021 11.
Artigo em Inglês | MEDLINE | ID: mdl-34339021

RESUMO

In the present study, we aimed to compare clinical and radiological findings between patients with and without pulmonary embolism (PE) and determine possible risk factors for PE development among patients with cancer. This was a retrospective study that examined the clinical features and tomographic findings of patients with cancer who underwent thoracic tomography for suspected PE. A total of 487 cases were included in the study. Of which, 45 (9.2%) patients were found to have PE. The effect of gender on PE was found to be significant (p = 0.018). Patients with PE compared to those without PE are 2.828 times more likely to be women than men. It was determined that the probability of not having a history of coronary artery disease (CAD) was 2.930 times (p = 0.036), probability of shortness of breath was 4.153 times (p < 0.001), syncope/presyncope was 6.859 times (p = 0.007), and palpitation was 5.613 times (p = 0.040) more in those with PE compared to those without PE. The mean pulse rate per minute was significantly higher in patients with PE than in those without (p = 0.009). Ninety-one percent of patients had parenchymal abnormalities, 43.7% had mediastinal and cardiovascular abnormalities, 35.5% had pleural abnormalities, 32.9% had thoracic wall abnormalities (p = 0.109, p < 0.001, p = 0.022, p = 0.685, respectively). Our study demonstrated that patients with PE were more likely to be women, patients with a history of palpitations, shortness of breath, syncope/presyncope, and those not having a history of CAD. More comprehensive studies are required in the future to clearly identify the risk factors for PE in patients with cancer and clarify the indications for tomography.


Assuntos
Tomografia Computadorizada Multidetectores , Neoplasias/complicações , Embolia Pulmonar/diagnóstico por imagem , Radiografia Torácica , Idoso , Idoso de 80 Anos ou mais , Antineoplásicos/uso terapêutico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias/tratamento farmacológico , Neoplasias/patologia , Neoplasias/fisiopatologia , Valor Preditivo dos Testes , Prognóstico , Embolia Pulmonar/etiologia , Estudos Retrospectivos , Medição de Risco , Fatores de Risco , Fatores Sexuais , Fatores de Tempo
12.
Am J Emerg Med ; 44: 203-207, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-32220526

RESUMO

BACKGROUND: Acute pancreatitis is the inflammation of the pancreas. It can range from mild forms to life-threatening severe cases. There is not yet a marker that can detect severe cases in the early period. Early diagnosis and treatment of this disease has critical importance for prognosis. In this study, we aimed to investigate the percentage of immature granulocyte (IG %) in patients with acute pancreatitis in order to predict the severity of the disease and in-hospital mortality. METHOD: This study was carried out retrospectively in academic emergency department (ED), faculty of medicine between 01.01.2017 and 30.06.2019. The patients were divided into three groups as mild, moderate and severe. In addition, the patients were divided into two groups: those discharged from the hospital and those who died in the hospital. IG % and other laboratory parameters of the patients were recorded in the study form. The primary outcome for this study is the value of IG% in predicting severity in AP patients. A receiver operating characteristic (ROC) curve analysis was performed. RESULTS: A total of 218 patients (107 male) were included in the study. The mean age of the patients was 56.9 ± 18.3 years. It was found that IG% levels were higher in patients with severe pancreatitis (p = .018). In the ROC analysis that was done to determine the severity of the disease, the cut-off value of IG% was found as >1.1. As such case, specificity was %38.89, sensitivity was 95.00%, positive predictive value (PPV) was 41.18% and negative predictive value (NPV) was found as 94.53% (Area Under Curve (AUC) = 0.698). In ROC analysis that was performed to determine in-hospital mortality, the cut-off value of IG level was found as >1.8, sensitivity was 50.00%, specificity was 97.12%, PPV was 45.45% and NPV was found as 97.58% (AUC = 0.708). CONCLUSiONS: This study shows that higher IG% levels may correlate with higher disease severity and in-hospital mortality in patients with acute pancreatitis.


Assuntos
Serviço Hospitalar de Emergência , Granulócitos/metabolismo , Pancreatite/sangue , Pancreatite/mortalidade , Biomarcadores/metabolismo , Feminino , Mortalidade Hospitalar , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Prognóstico , Estudos Retrospectivos , Sensibilidade e Especificidade , Índice de Gravidade de Doença , Turquia
13.
Cardiovasc Toxicol ; 21(1): 49-58, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-32895868

RESUMO

The neurohumoral and inflammatory pathways proposed for the development and progression of heart failure (HF) remain up-to-date. We aimed to investigate the effect of emergency department (ED) visits and inflammatory markers on mortality in HF patients. Two-hundred patients with stable chronic HF followed by the cardiology clinic were included in this study. The patients were divided into two groups as patients who had visited the ED due to worsening HF symptoms within the last 6 months (ED visit Group) and who had not (No ED visit Group). The demographical properties, clinical characteristics, and laboratory values including inflammatory markers of the patients were recorded. During the follow-up period, 38 patients (19%) died. In HF patients with previous ED visits, the mortality risk was 2.091 times higher (relative risk, RR). It was identified that the HF patients who died during the follow-up had higher initial NLR (p = 0.004), IG% (p = 0.029), hs-CRP (p = 0.001), and NT-proBNP (p = 0.004) values. It was observed that the area under the curve (AUC) values, NLR (AUC: 0.705, p < 0.001), IG% (AUC: 0.652, p = 0.003), and hs-CRP (AUC: 0.732, p < 0.001) were very strong predictors of the 1-year mortality. According to the cut-off points, the mortality risk (RR) was 3.39 times higher in patients with NLR > 3.7 (95% CI 1.783-6.444), 2.39 times higher when IG% > 0.4 (95% CI 1.16-4.957), and 4,2 times higher when hs-CRP > 9.9 mg/dl (95% CI 2.16-8.16) (p < 0.05). The patients with chronic stable HF who visited the ED within the last six months and having increased NLR, IG%, and CRP levels among inflammatory markers were associated with a higher mortality risk at 1 year.


Assuntos
Serviço Hospitalar de Emergência , Insuficiência Cardíaca/sangue , Insuficiência Cardíaca/mortalidade , Mediadores da Inflamação/sangue , Inflamação/sangue , Inflamação/mortalidade , Idoso , Biomarcadores/sangue , Comorbidade , Progressão da Doença , Feminino , Insuficiência Cardíaca/diagnóstico , Insuficiência Cardíaca/terapia , Humanos , Inflamação/diagnóstico , Masculino , Pessoa de Meia-Idade , Prognóstico , Estudos Retrospectivos , Medição de Risco , Fatores de Risco , Fatores de Tempo
14.
Pediatr Int ; 63(3): 295-299, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33118657

RESUMO

BACKGROUND: Renal scarring is a serious complication in recurrent urinary tract infections (UTIs). Vitamin D deficiency has also been reported to be a risk factor for UTIs although, to date, no association between vitamin D deficiency and renal scarring has yet been identified. In the present study, it was investigated whether vitamin D deficiency may be a risk factor for renal scarring in patients with recurrent UTIs. METHODS: The study included patients between the ages of 1 and 18 years who were admitted to the pediatric nephrology department of the center between November 1, 2018 and November 1, 2019 and who were diagnosed with recurrent UTIs. The medical records of the patients were reviewed for the collection of demographic data, vitamin D levels, ultrasonography results and scintigraphic investigations with 99m-technetium dimercaptosuccinic acid (99m Tc-DMSA). The patients were divided into two groups: those with and without renal scarring, diagnosed via 99m Tc-DMSA. The vitamin D levels and other parameters of the two groups were compared. RESULTS: Vitamin D deficiency (<20 ng/mL) was observed in 73.9% of the patients without renal scarring, and in 94.1% of those with renal scarring (P = 0.015). A logistic regression analysis revealed vitamin D deficiency to be an independent risk factor for renal scarring in patients with recurrent UTIs (OR = 0.796 [0.691-0.917]). CONCLUSIONS: Vitamin D deficiency is found to be a risk factor for renal scarring in patients with recurrent UTIs. Vitamin D treatment may contribute to the prevention of renal scarring in patients with recurrent UTI.


Assuntos
Infecções Urinárias , Refluxo Vesicoureteral , Deficiência de Vitamina D , Adolescente , Criança , Pré-Escolar , Cicatriz/etiologia , Humanos , Lactente , Rim/patologia , Recidiva , Fatores de Risco , Ácido Dimercaptossuccínico Tecnécio Tc 99m , Infecções Urinárias/complicações , Infecções Urinárias/patologia , Deficiência de Vitamina D/complicações
15.
J Addict Nurs ; 30(1): 49-56, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30830000

RESUMO

BACKGROUND: Digital game addiction among adolescents is a growing problem. The purpose of this study is to describe the predictors for this addiction in a group of Turkish adolescents using a conceptual framework. METHODS: A descriptive correlational study was conducted on 865 students (aged 11-16 years) and their parents. Self-reported digital game behaviors were measured using the Game Addiction Scale. The risk factors for gaming addiction were examined using multiple regression analysis. RESULTS: Adolescents spent 10.78 ± 13.42 hours per week playing digital games, and the rate of digital game addiction was calculated at 4.32% and 28.8% in monothetic and polythetic formats, respectively. Family environment and school performance directly affected female adolescents' digital gaming behaviors, whereas male adolescents' digital gaming behaviors were directly affected by computer self-efficacy, psychosocial problems, diminished impulse control, and levels of in-game violence. CONCLUSIONS: The interaction model of client health behavior can be used to describe adolescents' digital game use. Nurses can assess adolescents' gaming behaviors and use the effective predictors from the male and female models to develop intervention programs.


Assuntos
Comportamento do Adolescente/psicologia , Comportamento Aditivo/psicologia , Jogos de Vídeo/efeitos adversos , Adolescente , Adulto , Correlação de Dados , Feminino , Humanos , Masculino , Modelos Teóricos , Análise de Regressão , Fatores de Risco , Fatores Sexuais , Inquéritos e Questionários , Turquia , Adulto Jovem
16.
Surg Radiol Anat ; 41(2): 153-159, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30367188

RESUMO

PURPOSE: The aims of the study are to define anatomy of the facial nerve (FN) and its main trunks as well as their relationship with the posterior auricular artery in fetal period to evaluate the data for regional surgery in newborns and young infants. METHODS: Formalin-fixed 34 fetuses from anatomy laboratory collection with a mean gestational age of 26.4 ± 4.6 (20-36) weeks were dissected. Parameters regarding the presence of major or minor trunks, width, length, branching pattern of FN were evaluated according to side, gender and trimester. The positional relationship of posterior auricular artery with the FN trunk was inspected. RESULTS: On all sides only the major trunk of the FN was detected. For length and width parameters, there was no statistically significant difference for side and gender except for trimester. Linear functions were found as 0.329 + 0.025 × weeks for width and 5.264 + 0.185 × weeks for length. There are statistically significant linear relationships between width and length of the FN trunk and week parameters as r = 0.507, p < 0.001 and r = 0.484, p < 0.001, respectively. Posterior auricular artery crossed FN trunk laterally in 42 of 53 sides, medially in 9 sides while it was puncturing it proximally in 2 sides. In all cases, it was in close contact to the FN trunk. FN trunk showed bifurcation in 82% and trifurcation in 18%. CONCLUSION: Dimensions of FN trunk, growth ratio and linear functions can be beneficial in understanding the fetal growth of FN trunk and its usage for grafts. Data about the relationship of the posterior auricular artery with FN trunk may be crucial in avoiding iatrogenic injuries during surgery in early ages.


Assuntos
Artéria Carótida Externa/anatomia & histologia , Nervo Facial/anatomia & histologia , Feto/anatomia & histologia , Cadáver , Artéria Carótida Externa/embriologia , Nervo Facial/embriologia , Humanos
17.
Florence Nightingale Hemsire Derg ; 27(1): 38-47, 2019 Feb.
Artigo em Turco | MEDLINE | ID: mdl-34267961

RESUMO

AIM: To manage and document the nursing care process related to Surgical Site Infection and control in colorectal cancer patient using the Turkish-Nightingale Notes (T-NN) program and test the usability of the program. METHOD: The sample of the study consisted of 30 patients who underwent colorectal surgery in a university hospital between 1 March and 31 October 2015. All nursing care data provided at hospital and during discharge are coded into the NN program based on the Omaha System. Analyzes were performed using descriptive statistical tests in the SPSS 22 program. RESULTS: The 56.7% of patients were women and 43.3% were men. Four patients in thirty were diagnosed by surgical site infection (13.3%). The nine nursing problems were chosen from the T-NN program were 51.1% "Skin", 13,2% "Communicable/infectious Condition", 9.4% "Nutrition" and 0.2% "Sexuality". In the solution of the problems, "Teaching Guidance, and Counseling; Treatments and Procedures; Case Management and Surveillance initiatives were used. Nursing care/ patient outcomes were assessed at the level of "Knowledge", "Behavior" and "Status". Significant improvement was observed at the level of "Knowledge" and "Behavior" in the patients who underwent surgery for potential problems at all levels in patients who developed Surgical Site Infection (CAE) (p<0.001). CONCLUSION: Turkish-Nightingale Notes (T-NN) program was sufficient to describe the nursing care process for CAE in colorectal surgery patients. T-NN program could be used by infection control nurses. It was suggested that the program be used in different units and with different problems and samples. These efforts can provide the opportunity to use common language in nursing, to base evidence of nursing practices and to reveal the value of nursing care.

18.
Surg Radiol Anat ; 40(8): 881-889, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-29143863

RESUMO

PURPOSE: Although latissimus dorsi (LD) flaps are extensively used in a wide range of interventions, fetus studies on this subject are quite limited. This study aims to obtain detailed information about the morphometric features of LD, thoracodorsal artery (TDA) and nerve (TDN). METHODS: The study was carried out on both sides of 50 formalin-fixed human fetuses (22 male/28 female) with a mean gestational age of 24.5 ± 4.7 (range 18-36) weeks, which were in the inventory of Anatomy Department of Mersin University Faculty of Medicine. Dimensions of LD, lengths and width of TDA and TDN were measured. Surface area of LD was calculated using digital image analysis software. RESULTS: All samples had LD muscle. Neither gender nor side-significant differences were observed in relation with the numerical data of LD, TDN and TDA. Linear function of surface area was calculated as "y = - 1767.532 + 114.582 × Age (weeks)". LD was attached directly to the posterior part of iliac crest in 59 of 100 sides meanwhile in the rest 41, it was attached by the thoracolumbar fascia. TDA gave a branch to serratus anterior in 96 cases and 2 branches in 4 cases. TDN passed superficial to TDA in 84 and deep to TDA in 16 samples. TDN had bifurcation in 93, trifurcation in 6 and tetrafurcation in 1 side. CONCLUSION: Data obtained from this study can be useful for estimating the sizes of LD and related neurovascular structures, especially in neonate surgeries. Linear function of LD surface area can be helpful to design the flap dimensions in newborn surgeries. A throughout knowledge about the branching pattern of TDN and its location-wise relation with TDA should be kept in mind to prevent possible complications during harvesting LD flaps and TDN grafts.


Assuntos
Artérias/anatomia & histologia , Feto/anatomia & histologia , Músculos Superficiais do Dorso/anatomia & histologia , Cadáver , Feminino , Humanos , Masculino , Músculos Superficiais do Dorso/transplante , Retalhos Cirúrgicos/irrigação sanguínea , Retalhos Cirúrgicos/inervação , Retalhos Cirúrgicos/transplante
19.
J Child Neurol ; 32(14): 1083-1091, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29129152

RESUMO

PURPOSE: We aimed to (1) compare quality of life (QOL) among children with epilepsy, epilepsy and attention-deficit hyperactivity disorder (ADHD), and primary ADHD and (2) compare ADHD symptom dimensions and subtypes between children with epilepsy-ADHD and primary ADHD. METHODS: A total of 140 children; 53 with epilepsy, 35 with epilepsy-ADHD, and 52 with primary ADHD were included. KINDL-R (quality of life measure), Turgay DSM-IV Disruptive Behavior Disorders Rating Scale (T-DSM-IV-S), and Conners' Parent Rating Scale (CPRS) were completed. Neurology clinic charts were reviewed for epilepsy-related variables. RESULTS: Children with epilepsy-ADHD had the lowest (poorest) KINDL-R total scores. Epilepsy-ADHD group had more inattentiveness symptoms, whereas primary ADHD group had more hyperactivity/impulsivity symptoms. The frequencies of ADHD combined and inattentiveness subtypes were 60% and 40% in children with epilepsy-ADHD and 80.7% and 19.3% in children with primary ADHD, respectively ( P = .034). CONCLUSION: ADHD in epilepsy is associated with a significantly poor quality of life and predominantly inattentiveness symptoms.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade/complicações , Transtorno do Deficit de Atenção com Hiperatividade/psicologia , Epilepsia/complicações , Epilepsia/psicologia , Adolescente , Criança , Estudos de Coortes , Estudos Transversais , Eletroencefalografia , Feminino , Humanos , Testes de Inteligência , Masculino , Pais/psicologia , Escalas de Graduação Psiquiátrica , Qualidade de Vida , Índice de Gravidade de Doença
20.
Epilepsy Behav ; 71(Pt A): 7-12, 2017 06.
Artigo em Inglês | MEDLINE | ID: mdl-28437682

RESUMO

AIMS: Attention-deficit hyperactivity disorder (ADHD) is a frequent comorbidity in pediatric epilepsy. Although sleep problems are commonly reported in both children with primary ADHD and epilepsy, those with epilepsy-ADHD comorbidity have not been well studied. This study aimed to compare sleep problems among three groups of children: 1) children with epilepsy, 2) children with epilepsy and ADHD (epilepsy-ADHD), and 3) children with primary ADHD. METHODS: 53 children with epilepsy, 35 children with epilepsy-ADHD, and 52 children with primary ADHD completed the Children's Sleep Habits Questionnaire (CSHQ). Neurology clinic charts were reviewed for the epilepsy-related variables. ADHD subtypes were diagnosed according to the DSM-IV. RESULTS: Children with epilepsy-ADHD had the highest CSHQ total scores, while children with primary ADHD had higher scores than those with epilepsy. Besides the total score, epilepsy-ADHD group differed from the primary ADHD and epilepsy groups with higher CSHQ subscores on sleep onset delay and sleep anxiety. The frequency of moderate-severe sleep problems (CSHQ>56) was 62.9% in children with epilepsy-ADHD, while it was 40.4% and 26.4% in children with primary ADHD and epilepsy, respectively. CSHQ total scores were not different between ADHD subtypes in both children with epilepsy-ADHD and those with primary ADHD. None of the epilepsy-related variables were found to be associated with CSHQ scores. DISCUSSION: Epilepsy-ADHD is associated with a significantly poor sleep quality which is beyond that of primary ADHD and epilepsy.


Assuntos
Transtorno do Deficit de Atenção com Hiperatividade/diagnóstico , Transtorno do Deficit de Atenção com Hiperatividade/epidemiologia , Epilepsia/diagnóstico , Epilepsia/epidemiologia , Transtornos do Sono-Vigília/diagnóstico , Transtornos do Sono-Vigília/epidemiologia , Adolescente , Transtorno do Deficit de Atenção com Hiperatividade/psicologia , Criança , Estudos de Coortes , Comorbidade , Estudos Transversais , Epilepsia/psicologia , Feminino , Hábitos , Humanos , Masculino , Sono/fisiologia , Transtornos do Sono-Vigília/psicologia , Inquéritos e Questionários
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