[Acute intermittent porphyria in the practice of anesthesiology and intensive care]. / Ostraia peremezhaiushchaiasia porfiriia v praktike anesteziologa-reanimatologa.

Acute intermittent porphyria (AIP) is a hereditary disease caused by disordered haem biosynthesis and characterized by paroxysmal exacerbations. It usually manifests in adult women. Provoking factors are pregnancy, alcohol, and "porphyrogenic" drugs. Grave attacks of AIP require urgent hospitalization in intensive care wards, rapid purposeful diagnosis and adequate therapy, determining the prognosis. The number of drugs should be minimized and drugs with a known porphyrogenic effect absolutely ruled out. A 35-year-old patient with the first episode of AIP is described; the disease eventuated in death after 2 months.

[The etiological and pathogenetic characteristics of nosocomial pneumonia related to AMV (NP AMV)]. / Etiologicheskie i patogeneticheskie osobennosti nozokomial'noi pnevmonii, sviazannoi s IVL (NP IVL).

The author reviews modern data on the classification, epidemiology, etiology, and main risk factors of ventilator-associated pneumonias, the most severe complication of prolonged artificial ventilation of the lungs. Special attention is paid to the pathogenesis of this type of nosocomial pneumonia.

[Acute intermittent porphyria in the practice of an intensive care specialist]. / Ostraia peremezhaiushchaiasia porfiriia v praktike vracha-reanimatologa.

Acute intermittent porphyria (AIP) is a hereditary disease caused by disordered haem biosynthesis and characterized by paroxysmal exacerbations. It usually manifests in adult women. Provoking factors are pregnancy, alcohol, and "porphyrogenic" drugs. Grave attacks of AIP require urgent hospitalization in intensive care wards, rapid purposeful diagnosis and adequate therapy, determining the prognosis. The number of drugs should be minimized and drugs with a known porphyrogenic effect absolutely ruled out. A 35-year-old patient with the first episode of AIP is described; the disease eventuated in death after 2 months.

[Mycotic infections in the practice of an intensive care specialist]. / Mikoticheskie infektsii v praktike vracha-reanimatologa.

The authors report their experience gained in intensive care of patients with a grave complication of the underlying diseases: disseminated mycotic infection. Factors of risk of the complication are enumerated, diagnosis and treatment of mycotic involvement in patients of intensive care wards are described.

[Diagnosis of the stages of endogenous toxemia and differentiated use of of the methods of efferent therapy ]. / Diagnostika stadii éndogennoi intoksikatsii i differentsirovannoe primenenie metodov éfferentnoi terapii.

The work is supposed to estimate intoxication by summary indices of the medium and low mass molecules and oligopeptides in plasma, erythrocytes and urine. The indices developed made it possible to determine the stage of endogenous intoxication and to choose differentially the optimal methods of efferent therapy or a combination of methods.