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1.
Int J Mol Sci ; 23(6)2022 Mar 09.
Artigo em Inglês | MEDLINE | ID: mdl-35328367

RESUMO

The need for more sustainable printed electronics has emerged in the past years. Due to this, the use of nanocellulose (NC) extracted from cellulose has recently been demonstrated to provide interesting materials such as functional inks and transparent flexible films due to its properties. Its high specific surface area together with the high content of reactive hydroxyl groups provide a highly tailorable surface chemistry with applications in ink formulations as a stabilizing, capping, binding and templating agent. Moreover, NC mechanical, physical and thermal properties (high strength, low porosity and high thermal stability, respectively) provide an excellent alternative for the currently used plastic films. In this work, we present a process for the production of water-based conductive inks that uses NC both as a template for silver nanoparticles (Ag NPs) formation and as an ink additive for ink formulation. The new inks present an electrical conductivity up to 2 × 106 S/m, which is in the range of current commercially available conductive inks. Finally, the new Ag NP/NC-based conductive inks have been tested to fabricate NFC antennas by screen-printing onto NC-coated paper, demonstrating to be operative.


Assuntos
Tinta , Nanopartículas Metálicas , Condutividade Elétrica , Eletrônica , Excipientes , Nanopartículas Metálicas/química , Prata/química , Água
3.
J Morphol ; 281(3): 326-337, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-31984547

RESUMO

The development of caenolestid marsupials (order Paucituberculata) is virtually unknown. We provide here the first description of Caenolestes fuliginosus embryos collected in the Colombian Central Andes. Our sample of four embryos comes from a single female caught during a fieldtrip at Río Blanco (Manizales, Caldas), in 2014. The sample was processed for macroscopic description using a Standard Event System and for histological descriptions (sectioning and staining). The grade of development of the lumbar flexure and coelomic closure differed between embryos, two of them being more advanced than the others (similar to McCrady's stages 30 and 29, respectively). The pericardial and peritoneal cavities were present, the hepatic anlage was organized in hepatic cords, the heart was in its final position, and the mesonephros was functional. Compared to other Neotropical marsupials, an early appearance of the frontonasal-maxillary fusion and the cervical growth (thickness) was observed; however, absorption of the pharyngeal arches into the body and lung development was delayed. Besides these differences, embryos were similar to equivalent stages in Didelphis virginiana and Monodelphis domestica. Previous proposals of litter size of four for C. fuliginosus are supported.


Assuntos
Embrião de Mamíferos/anatomia & histologia , Gambás/embriologia , Animais , Embrião de Mamíferos/citologia , Feminino , Mesonefro/anatomia & histologia , Mesonefro/citologia , Mesonefro/embriologia , Organogênese
5.
Vaccine ; 31(7): 1100-5, 2013 Feb 04.
Artigo em Inglês | MEDLINE | ID: mdl-23261048

RESUMO

We conducted a phase I, double-blind, placebo-controlled trial to evaluate a new 5-valent oral rotavirus vaccine's safety and immunogenicity profiles. Subjects were randomly assigned to receive 3 orally administered doses of a live-attenuated human-bovine (UK) reassortant rotavirus vaccine, containing five viral antigens (G1, G2, G3, G4 and G9), or a placebo. The frequency and severity of adverse events were assessed. Immunogenicity was evaluated by the titers of anti-rotavirus IgA and the presence of neutralizing antibodies anti-rotavirus. No severe adverse events were observed. There was no difference in the frequency of mild adverse events between experimental and control groups. The proportion of seroconversion was consistently higher in the vaccine group, for all serotypes, after each one of the doses. The 5-valent vaccine has shown a good profile of safety and immunogenicity in this small sample of adult volunteers.


Assuntos
Vacinas contra Rotavirus/efeitos adversos , Vacinas contra Rotavirus/imunologia , Administração Oral , Adolescente , Adulto , Anticorpos Neutralizantes/sangue , Anticorpos Antivirais/sangue , Método Duplo-Cego , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/epidemiologia , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/patologia , Feminino , Humanos , Imunoglobulina A/sangue , Masculino , Placebos/administração & dosagem , Vacinas contra Rotavirus/administração & dosagem , Vacinas Atenuadas/administração & dosagem , Vacinas Atenuadas/efeitos adversos , Vacinas Atenuadas/imunologia , Adulto Jovem
6.
Rev Med Chil ; 137(3): 390-3, 2009 Mar.
Artigo em Espanhol | MEDLINE | ID: mdl-19621181

RESUMO

Systemic lymphoma that involves the aorta is called periaortic lymphoma, and may be misdiagnosed clinically or in CT sean, mimicking a thoracic aortic aneurysm, dissection, penetrating ulcer or an intramural hematoma. We report a 70 year-old woman in whom a systemic non-Hodgkin 's lymphoma ivas diagnosed after she presented with the clinical features of an acute aortic syndrome. A CT sean showed the presence of a large thoracoabdominal periaortic soft tissue mass without aneurism or dissection. Later, a biopsy of the mass ivasperformed which showed a non-Hodgkin's lymphoma. Chemotherapy with CHOP-R was effective, with complete initial resolution of the mass, developing in the follow up chylothorax, malnutrition and death.


Assuntos
Aneurisma da Aorta Torácica/diagnóstico , Doenças da Aorta/diagnóstico , Linfoma não Hodgkin/diagnóstico , Idoso , Diagnóstico Diferencial , Feminino , Humanos , Tomografia Computadorizada por Raios X
7.
Rev. méd. Chile ; 137(3): 390-393, mar. 2009. ilus
Artigo em Espanhol | LILACS | ID: lil-518499

RESUMO

Systemic lymphoma that involves the aorta is called periaortic lymphoma, and may be misdiagnosed clinically or in CT sean, mimicking a thoracic aortic aneurysm, dissection, penetrating ulcer or an intramural hematoma. We report a 70 year-old woman in whom a systemic non-Hodgkin 's lymphoma ivas diagnosed after she presented with the clinical features of an acute aortic syndrome. A CT sean showed the presence of a large thoracoabdominal periaortic soft tissue mass without aneurism or dissection. Later, a biopsy of the mass was performed which showed a non-Hodgkin's lymphoma. Chemotherapy with CHOP-R was effective, with complete initial resolution of the mass, developing in the follow up chylothorax, malnutrition and death.


Assuntos
Idoso , Feminino , Humanos , Aneurisma da Aorta Torácica/diagnóstico , Doenças da Aorta/diagnóstico , Linfoma não Hodgkin/diagnóstico , Diagnóstico Diferencial , Tomografia Computadorizada por Raios X
8.
J. pediatr. (Rio J.) ; 73(5): 349-52, set.-out. 1997. ilus
Artigo em Português | LILACS | ID: lil-211793

RESUMO

Objetivo: Alertar os pediatras emergencistas para uma causa pouco comum de obstruçäo de vias aéreas em crianças submetidas a ventilaçäo mecânica. Métodos: Os autores relatam um caso de traqueobronquite necrotisante em lactente de 8 meses e discutem a fisiopatologia, diagnóstico e abordagem terapêutica. Resultados: A crianca apresentou evoluçäo favorável associado ao diagnóstico precoce e pronta intervençäo broncoscópica. Conclusöes: Os pediatras emergencistas devem suspeitar de traqueobronquite necrotisante em todas as crianças sob ventilaçäo mecânica que apresentarem o quadro clínico típico caracterizado por obstruçäo aguda das vias aéreas, hiperinsuflaçäo pulmonar, mesmo fora do período neonatal. Essa situaçäo, uma vez reconhecida, constitui indicaçäo precisa de traqueobroncoscopia de urgência...


Assuntos
Humanos , Masculino , Lactente , Obstrução das Vias Respiratórias , Brônquios/fisiologia , Respiração Artificial , Traqueia/fisiopatologia , Broncoscopia
9.
J. pediatr. (Rio J.) ; 72(4): 230-4, maio-jun. 1996. tab
Artigo em Português | LILACS | ID: lil-193344

RESUMO

Foram estudadas 28 crianças de 1 mês a 12 anos de idade com quadro séptico e hemocultura positiva para Klebsiella pneumoniae e comparadas com um grupo de crianças com sepse para outros patógenos ou sem etiologia definida. Constatou-se qeu a sepse por Klebsiella pneumoniae ocorreu mais freqüentemente em crianças maiores de 2 anos, näo havendo diferença em relaçäo ao sexo acometido. A maioria das crianças estudadas havia sido internada em hospital nos últimos trinta dias, era portadora de cateter central, 64,3 por cento dos casos com patologia de base, salientando-se as hepatopatias e doenças oncológicas. O quadro clínico inicial caracterizou-se principalmente por acometimento do trato respiratório (35,7 por cento) e por doença diarréica aguda (28,6 por cento). A letalidade foi alta dos dois grupos e o agente infeccioso näo aumentou o risco relativo de óbito. Verificou-se que as cepas isoladas de Klebsiella pneumoniae apresentaram bons índices de sensibilidade à colistina (92,9 por cento) e à cefoxitina (82,1 por cento) e baixos índices às cefalosporinas de 3ª geraçäo e ao imipenen.


Assuntos
Humanos , Criança , Cefoxitina , Cefalosporinas , Colistina , Klebsiella pneumoniae , Sepse , Hepatopatias , Patologia
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