Exitoso tratamiento con queratoprótesis de Boston en un paciente con síndrome de Lyell / Successful Boston keratoprrosthesis in a patient with Lyell's syndrome

Caso clínico: Presentamos el caso de una pacienteque acude a nuestro servicio remitida por presentarun síndrome de Lyell con severa participación ocular.La intensa afectación de la superficie ocular y lainsuficiencia límbica sientan la indicación paraimplantar una queratoprótesis de Boston tipo 1,logrando un resultado funcional estable y muysatisfactorio.Discusión: Como se puede ver en este caso clínico,la queratoprótesis de Boston tipo 1 parece ser unaopción viable después de múltiples trasplantes cornealesfallidos o en algunas situaciones con pobrepronóstico para una queratoplastia penetrante primariapor presentar insuficiencia límbica, como elsíndrome de Lyell(AU)

Case report: We present the case of a woman readmittedto our service to receive treatment for severeophthalmic manifestations due to Lyell’s syndrome.This intense affectation of the ocular surface alongwith limbal stem cell deficiency are grounds for treatmentwith Boston type 1 keratoprosthesis, whichprovided a stable and very satisfactory functionalresult.Discussion: As noted in this case report, the BostonType 1 keratoprosthesis seems to be a viable optionafter multiple failed corneal grafts or in situationswith a poor prognosis for primary penetrating keratoplastybecause of limbal stem cell deficiency,such as Lyell’s syndrome(AU)

[Successful Boston keratoprosthesis in a patient with Lyell's syndrome]. / Exitoso tratamiento con queratoprótesis de Boston en un paciente con síndrome de Lyell.

CASE REPORT: We present the case of a woman readmitted to our service to receive treatment for severe ophthalmic manifestations due to Lyell's syndrome. This intense affectation of the ocular surface along with limbal stem cell deficiency are grounds for treatment with Boston type 1 keratoprosthesis, which provided a stable and very satisfactory functional result. DISCUSSION: As noted in this case report, the Boston Type 1 keratoprosthesis seems to be a viable option after multiple failed corneal grafts or in situations with a poor prognosis for primary penetrating keratoplasty because of limbal stem cell deficiency, such as Lyell's syndrome.

Influencia del LASIK en la capa de fibras nerviosas retinianas / Influence of LASIK on retinal nerve fiber layer

Objetivo: Estudiar la influencia de la queratomileusis asistida por láser (LASIK) en el grosor de capa de fibras nerviosas retinianas (CFNR). Métodos: 50 ojos miopes tratados mediante LASIK sin complicaciones. Medición de espesor de CFNR peripapilar preoperatorio y postoperatorio (2 semanas) mediante tomografía óptica de coherencia (OCT). Variables: grosor medio, superior, inferior, nasal y temporal. Comparación estadística entre valores preoperatorios y postoperatorios. Estudio de correlación entre el grado de miopía y el espesor de CFNR. Resultados: No existieron diferencias estadísticas significativas entre los valores preoperatorios y postoperatorios de grosor de CFNR en ninguna las variables estudiadas: espesor medio (77,6 DE 14 vs 81 DE 13,3), superior (103,1 DE 22,6 vs 105,4 DE 24,6), inferior (89,3 DE 28 vs 93,9 DE 23,1), nasal (53,7 DE 18,1 vs 56,1 DE 16) y temporal (64,74 DE 12,29 vs 67,3 DE 13,7) (P > 0,05 en todas las comparaciones; t de Student). Se demostró una correlación inversa entre el grado de miopía y el grosor de CFNR en todas las variables estudiadas: espesor medio (r= –0,45), superior (r= –0,42), inferior (r= –0,39), nasal (r= –0,26) y temporal (r= –0,09) (test de Pearson). Conclusiones: El espesor de CFNR medido mediante OCT no se afecta por el LASIK en el periodo de seguimiento(AU)

Purpose: Objective: To study the influence of laser-assisted in situ keratomileusis (LASIK) on retinal nerve fibre layer (RNFL) thickness. Methods: 50 myopic eyes treated with uncomplicated LASIK. Measurement of preoperatory and postoperatory (2 weeks) peripapillary RNFL thickness by optical coherence tomography (OCT). Study variables: mean, superior, inferior, nasal and temporal thickness. Statistical comparison between preoperatory and postoperatory values. Study of the correlation between the amount of myopia and RNFL thickness. Results: There were no statistical differences between preoperatory and postoperatory RNFL thickness values in any of the studied variables: mean (77.6 SD 14 vs 81 SD 13,3), superior (103.1 SD 22,6 vs 105.4 SD 24.6), inferior (89.3 SD 28 vs 93.9 SD 23.1), nasal (53.7 SD 18.1 vs 56.1 SD 16) and temporal thickness (64.74 SD 12.29 vs 67.3 SD 13.7) (P > 0.05 for all comparisons; Student's t test). There was an inverse correlation between the amount of myopia and RNFL thickness in all of the studied variables: mean (r=-0.45), superior (r=-0.42), inferior (r=-0.39), nasal (r=-0.26) and temporal thickness (r= -0.09) (Pearson's test). Conclusions: OCT-measured RNFL thickness remains unchanged after LASIK in the follow-up period(AU)

[Influence of LASIK on retinal nerve fiber layer]. / Influencia del LASIK en la capa de fibras nerviosas retinianas.

OBJECTIVE: To study the influence of laser-assisted in situ keratomileusis (LASIK) on retinal nerve fibre layer (RNFL) thickness. METHODS: 50 myopic eyes treated with uncomplicated LASIK. Measurement of preoperatory and postoperatory (2 weeks) peripapillary RNFL thickness by optical coherence tomography (OCT). STUDY VARIABLES: mean, superior, inferior, nasal and temporal thickness. Statistical comparison between preoperatory and postoperatory values. Study of the correlation between the amount of myopia and RNFL thickness. RESULTS: There were no statistical differences between preoperatory and postoperatory RNFL thickness values in any of the studied variables: mean (77.6 SD 14 vs 81 SD 13,3), superior (103.1 SD 22,6 vs 105.4 SD 24.6), inferior (89.3 SD 28 vs 93.9 SD 23.1), nasal (53.7 SD 18.1 vs 56.1 SD 16) and temporal thickness (64.74 SD 12.29 vs 67.3 SD 13.7) (P > 0.05 for all comparisons; Student's t test). There was an inverse correlation between the amount of myopia and RNFL thickness in all of the studied variables: mean (r= -0.45), superior (r= -0.42), inferior (r=-0.39), nasal (r= -0.26) and temporal thickness (r= -0.09) (Pearson's test). CONCLUSIONS: OCT-measured RNFL thickness remains unchanged after LASIK in the follow-up period.