1.
Bioorg Med Chem Lett
; 16(16): 4252-6, 2006 Aug 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16759857
RESUMO
The sulfamic acid phosphotyrosine mimetic was coupled with a previously known malonate template to obtain highly selective and potent inhibitors of HPTPbeta. Potentially hydrolyzable malonate ester functionalities were replaced with 1,2,4-oxadiazoles without a significant effect on HPTPbeta potency.