Impact of on-farm feeding practices on the reproductive indices of pigs reared under educated smallholder system in Imo State, Nigeria.

The aim of this study was to determine the impact of on-site feeding practices on the reproductive indices of pigs reared under educated smallholder system in Imo State, southeastern Nigeria. The smallholder pig farms (S1, S2, M, L1, and L2) visited were divided into small-, medium-, and large-size farms, with small farms stocking 70-80, medium 120-130, and larger 230-270 pigs. In each farm, six weaner pigs comprising Large White, Landrace, and Duroc breeds were selected and their ages and initial body weights determined. The feeds offered to the weaner pigs were physically characterized for their ingredient components. Thereafter, representative samples of the feeds were subjected to proximate biochemical analysis on the 1st, 7th, and 13th weeks of the study using standard methods. Results showed that all the farms utilized palm kernel cake as their major energy feedstuffs, in addition to soybean, common salt, local fish meal, and vitamins premix. Data generated were analyzed using analysis of variance and descriptive statistics (mean and percentages). The mean crude protein values of the feed samples collected from these farms were of similar range (13.49-14.20%), while crude fiber and ether extract values were very high. Data on calculated metabolizable energy values were also relatively low for growing pigs. There was significant (p < 0.05) differences in the final body weights of the grower pigs after 14 weeks of feeding across the farms. There were significant (p > 0.05) changes in weight gain, with farms S1, S2, M, L1, and L2 returning 24.50, 10.00, 67.50, 11 00, and 7.50 kg mean weights, respectively. There is a slight increment in birth weight of piglets in farms S1, S2, M, and L2 when compared with those in farm L1. Direct observations revealed that farms S1, L1, and L2 practiced flushing techniques which invariably resulted in higher litter size recorded in these farms. The dams in farms S1, L1, and L2 were observed to gain more weight during gestation and shed little during lactation.

Effect of aerobic exercise training on cardiovascular parameters and CD4 cell count of people living with human immunodeficiency virus/acquired immune deficiency syndrome: a randomized controlled trial.

OBJECTIVE: Despite the significant positive effect of Highly Active Antiretroviral Therapy on physical and psychosocial well-being of people living with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) (PLWHA); decreased physical activity and its associated cardiovascular risk still pose some consequences for health and general well-being. This study investigated the effect of an 8 week aerobic exercise training on cardiovascular parameters and CD4 cell (T-cells) count of PLWHA. MATERIALS AND METHODS: This randomized controlled trial recruited 30 age matched PLWHA who were randomly assigned into exercise group (EG) ( n = 15) and control group (CG) ( n = 15) respectively. The PLWHA were patients receiving treatment in President's Emergency Plan for AIDS relief at the HIV clinic of the University of Nigeria Teaching Hospital, Nigeria. The EG in addition to conventional therapy received moderate intensity continuous exercise training (60-79% of the maximum heart rate [max]) of between 45 and 60 min, 3 times/week for 8 weeks, while the CG received conventional therapy involving antiretroviral therapy and counseling only. Systolic blood pressure (SBP), diastolic blood pressure (DBP), maximum oxygen uptake (VO2 max) and CD4 cell count were assessed at baseline (week 1) and week 8 respectively. Analysis of co-variance and Pearson correlation tests were used in data analysis. RESULTS: Findings of the study revealed a significant effect (ANCOVA test) of moderate intensity continuous exercise training program on, SBP, DBP, VO2 max and CD4 cell count at P < 0.05. Changes in VO2 max significantly correlated (Pearson correlation test) with changes in CD4 cell count ( r = 0.528) at P < 0.05. CONCLUSION: Moderate intensity aerobic exercise is an effective complementary therapy in lowering blood pressure and increasing CD4 cell count in PLWHA.

Effect of probiotic (Saccharomyces cerevisiae) supplementation on immune response in Trypanosoma brucei brucei infected rats.

The immunomodulatory effect of the probiotic (Saccharomyces cerevisiae) on Trypanosoma brucei brucei infected rats was studied. Thirty (30) rats divided into five groups (A-E) of 6 rats each were used for the study. Groups A, B and C rats received feed supplemented with S. cerevisiae (at 0.08, 0.12 and 0.16/kg of feed, respectively) for the duration of the study. Groups D and E diets were not supplemented. All the rats in the 5 groups were immunized with 0.3 ml of 10% sheep red blood cells (SRBC) at day 7 pre-supplementation, and booster doses given every 14 days thereafter. On day 28 post supplementation (PS), rats of groups A-D were infected with 1 × 10(6) of T. brucei brucei intraperitoneally. Supplementation resulted in increases in antibody titres to SRBC which later declined following T. brucei brucei infection, but remained higher than the pre supplementation titres. At termination of the study (i.e. day 49 PS) supplemented groups had significantly (p<0.05) higher antibody titres than either the infected or the non infected controls. The total and differential leucocyte counts followed a similar pattern with initial increases in counts following supplementation followed by reductions after T. brucei brucei infection. Supplementation also resulted in decline in parasitaemia with significant difference between the supplemented groups and the un-supplemented controls on day 42 post infection. The results are indication that probiotics can be used to ameliorate the immunosuppressive effect of T. brucei brucei infections.