Dermoscopic features of neoplasms in skin of color: A review.

BACKGROUND: Dermoscopy is undoubtedly a useful tool to improve diagnostic accuracy and minimize the number of unnecessary biopsies. However, much of the literature on dermoscopy focuses on findings in lighter-skin phototypes, leaving potential gaps of knowledge regarding its use in skin of color (SoC). As the clinical applications of dermoscopy continue to increase, understanding dermoscopic patterns in SoC is imperative. OBJECTIVE: This review discusses the literature on dermoscopic findings of neoplasms in SoC, highlighting unique and characteristic dermoscopic features. METHODS: A literature review was performed using the PubMed database. Case reports, case series, case-control studies, and systematic reviews were included. RESULTS: A total of 8326 studies were identified based on the selected search terms, and 41 were included in this review based on relevance. CONCLUSION: There are specific dermoscopic characteristics in SoC for benign nevi, acral lentiginous melanoma, ethnic melanonychia, and dermatofibroma; however, there is a lack of published data about specific features of cutaneous melanoma, subungual melanoma, pigmented basal cell carcinoma, and pigmented squamous cell carcinoma in SoC. Because pigmented basal cell carcinoma, pigmented squamous cell carcinoma, ethnic melanonychia, and acral lentiginous melanoma are diagnosed at later stages in this population, it is important to understand their dermoscopic features. Further descriptive studies are needed to better characterize unique dermoscopic features in neoplasms in SoC.

Transrectal ultrasound guided prostate biopsy in university of Benin teaching hospital: effect of prostate volume on pain amongst Nigerian patients.

Prostate volume has been reported to have an effect on the severity of pain during prostate biopsy. This study assessed the effect of prostate volume on pain during TRUS guided prostate biopsy when apical peri-prostatic block is compared with intra-rectal xylocaine gel. This was a prospective randomized study which involved 90 patients. Group (A) had 2% intra-rectal plain xylocaine gel instillation, while Group (B) had peri-prostatic block with 1% plain xylocaine infiltration. Both groups were further stratified into prostate volume of < 50 mls and ≥50 mls. An 11 point visual analogue scale was used to assess pain during probe insertion, biopsy and 1 hour after biopsy. The mean pain score analyzed for each group. The mean pain score for Group (A) patients with prostate volume < 50 mls was 3.22.2, 7.31.7 and 2.11.4 during probe insertion, biopsy, and one hour after biopsy respectively. For Group (A) patients with prostate volume ≥50 mls, the mean pain score recorded was 2.81.8, 5.71.6, and 2.31.8 during probe insertion, biopsy and one hour after biopsy respectively (P{during biopsy} = 0.003). For Group B patients, the mean pain score during probe insertion, biopsy and one hour after biopsy for patients with prostate volume < 50 mls was 3.11.8, 2.81.7, 1.00.6 respectively. While for patients with prostate volumes ≥50 mls, the mean pain scores were 2.91.8, 3.21.8 and 1.30.9 respectively. This study revealed that prostate volume did not affect the severity of pain during prostate biopsy when apical peri-prostatic block was used as the anesthetic agent. Significantly reduced pain during trans-rectal ultrasound guided biopsy of the prostate for all prostate volumes. Intra-rectal xylocaine though inferior to peri-prostatic block was more effective for patients with prostate volume ≥50 mls.

Unusual Intravesical Foreign Body Following Perineo-vesical Injury.

Reports of foreign body in the bladder are rare. Various objects have been retrieved. Diagnosis is mainly by history of lower urinary tract symptoms and low abdominal pain combined with relevant radiological investigations. Treatment depends on the size, nature, and configuration of the object. The approach may be endoscopic or through open surgery depending on the above highlighted factors.