[Biochemical recurrence in patients with prostate cancer after radical treatment. Comparative study of prostatectomy vs. radiotherapy]. / Recidiva bioquímica en los pacientes con cáncer de próstata después de tratamiento radical. Estudio comparativo entre prostatectomía y radioterapia.

OBJECTIVES: To compare the biochemical relapse-free survival between radical prostatectomy and radiotherapy in patients with localized prostate cancer of low and intermediate recurrence risk. METHODS: A retrospective study of 435 patients with localized prostate cancer, radical prostatectomy was performed in 65% of patients and radiotherapy was in 35%. The Kaplan-Meier Estimator was used to assess the biochemical relapse-free survival and long-rank test, Breslow and Tarone-Ware to evaluate the differences between the groups with confidence intervals at 95%. RESULTS: The median follow-up of the series was 60 months (3-106). Biochemical recurrence was diagnosed in 21% of patients: 22% of those were treated with prostatectomy and 19% with radiotherapy (p = 0.47). No significant differences were observed according to risk group (p = 0.60 in the low risk and p = 0.32 in the intermediate risk). Tree, five and seven-year actuarial biochemical recurrence-free survival for prostatectomy were 84%, 75%and 70%, while for radiotherapy were 97%, 84% and 64% respectively. CONCLUSIONS: There are no significant differences in actuarial biochemical recurrence free survival in patients with localized prostate cancer of low and intermediate risk treated with prostatectomy or radiation therapy. Due to the crossing of the survival curves we do not rule out that with longer follow-up these results could be modified.

Recidiva bioquímica en los pacientes con cáncer de próstata después de tratamiento radical. Estudio comparativo entre prostatectomía y radioterapia / Biochemical recurrence in patients with prostate cancer after radical treatment. Comparative study of prostatectomy vs. radiotherapy

OBJETIVO: Comparar la supervivencia libre de recidiva bioquímica entre la prostatectomía radical y la radioterapia en los pacientes con cáncer de próstata localizado de riesgo bajo e intermedio. MÉTODO: Estudio retrospectivo de 435 pacientes con cáncer de próstata localizado, el 65% tratado con prostatectomía y el 35% con radioterapia. El método de Kaplan-Meier se ha utilizado para evaluar la supervivencia libre de recidiva bioquímica y el test de long rank, Breslow y Tarone-Ware para evaluar sus diferencias entre los distintos grupos con sus intervalos de confianza al 95%. RESULTADOS: La mediana de seguimiento de la serie fue de 60 meses (3-106). Presentaron recidiva bioquímica el 21% de los pacientes, el 22% de los tratados con prostatectomía y el 19% de los tratados con radioterapia (p=0,47). No se observaron diferencias significativas en ambos grupos de riesgo en función del tratamiento realizado (p=0,60 en el de bajo riesgo y p=0,32 en el de riesgo intermedio). La supervivencia libre de recidiva bioquímica a los 3, 5 y 7 años para la prostatectomía fue del 84%, 75% y 70%, mientras que para la radioterapia fue del 97%, 84% y 64% respectivamente. CONCLUSIONES: No existen diferencias significativas en la supervivencia actuarial libre de recidiva bioquímica en los pacientes con cáncer de próstata localizado de riesgo bajo e intermedio tratados con prostatectomía o radioterapia. Debido al entrecruzamiento de las curvas de supervivencia no descartamos que con un seguimiento más prolongado estos resultados pudieran modificarse(AU)

OBJECTIVES: To compare the biochemical relapse-free survival between radical prostatectomy and radiotherapy in patients with localized prostate cancer of low and intermediate recurrence risk. METHODS: A retrospective study of 435 patients with localized prostate cancer, radical prostatectomy was performed in 65% of patients and radiotherapy was completed in 35%. The Kaplan-Meier Estimator was used to assess the biochemical relapse-free survival and long-rank test, Breslow and Tarone-Ware to evaluate the differences between the groups with confidence intervals at 95%. RESULTS: The median follow-up of the series was 60 months (3-106). Biochemical recurrence was diagnosed in 21% of patients: 22% of those were treated with prostatectomy and 19% with radiotherapy (p = 0.47). No significant differences were observed according to risk group (p = 0.60 in the low risk and p = 0.32 in the intermediate risk). Tree, five and seven-year actuarial biochemical recurrence-free survival for prostatectomy were 84%, 75% and 70%, while for radiotherapy were 97%, 84% and 64% respectively. CONCLUSIONS: There are no significant differences in actuarial biochemical recurrence free survival in patients with localized prostate cancer of low and intermediate risk treated with prostatectomy or radiation therapy. Due to the crossing of the survival curves we do not rule out that with longer follow-up these results could be modified(AU)

[Evaluation of the irrigation and drainage capacity of 3 bladder irrigation catheters]. / Evaluación de la capacidad de irrigación y drenaje de tres sondas de lavado vesical.

OBJECTIVES: To perform a comparative evaluation of three types of continuous bladder irrigation catheters with the aim of determining which of them allows greater irrigation solution inflow and bladder outflow. METHODS: We compared three types of three-way catheters, 22F in caliber, being the material the main difference between them: latex, silicone, or polyvinyl. RESULTS: The polyvinyl catheter showed significant differences both in inflow and outflow in comparison with the other two types of catheters (p = 0.000, ANOVA test with Sheffe's post hoc). Additionally, the latex catheter showed a significant outflow decrease with the insufflation of the self retentive balloon. CONCLUSIONS: The polyvinyl catheter, due to material rigidity, is the one that allows better bladder irrigation.