NCBO Resource Index: Ontology-Based Search and Mining of Biomedical Resources.

The volume of publicly available data in biomedicine is constantly increasing. However, these data are stored in different formats and on different platforms. Integrating these data will enable us to facilitate the pace of medical discoveries by providing scientists with a unified view of this diverse information. Under the auspices of the National Center for Biomedical Ontology (NCBO), we have developed the Resource Index-a growing, large-scale ontology-based index of more than twenty heterogeneous biomedical resources. The resources come from a variety of repositories maintained by organizations from around the world. We use a set of over 200 publicly available ontologies contributed by researchers in various domains to annotate the elements in these resources. We use the semantics that the ontologies encode, such as different properties of classes, the class hierarchies, and the mappings between ontologies, in order to improve the search experience for the Resource Index user. Our user interface enables scientists to search the multiple resources quickly and efficiently using domain terms, without even being aware that there is semantics "under the hood."

Supporting the Collaborative Authoring of ICD-11 with WebProtégé.

The World Health Organization (WHO) is well under way with the new revision of the International Classification of Diseases (ICD-11). The current revision process is significantly different from past ones: the ICD-11 authoring is now open to a large international community of medical experts, who perform the authoring in a web-based collaborative platform. The classification is also embracing a more formal representation that is suitable for electronic health records. We present the ICD Collaborative Authoring Tool (iCAT), a customization of the WebProtégé editor that supports the community based authoring of ICD-11 on the Web and provides features such as discussion threads integrated in the authoring process, change tracking, content reviewing, and so on. The WHO editors evaluated the initial version of iCAT and found the tool intuitive and easy to learn. They also identified improvement potentials and new requirements for large-scale collaboration support. A demo version of the tool is available at: http://icatdemo.stanford.edu.