RESUMO
In this study, the in vitro adherence capabilities of Pseudomonas aeruginosa and Candida albicans clinical isolates to urinary catheters were investigated. Quantitative analysis was performed by colony-forming unit counts and scanning electron microscopy. Results demonstrated that the adherence of P. aeruginosa to urinary catheters was enhanced in the presence of C. albicans, while C. albicans adherence was not significantly affected. Further investigations are warranted to fully understand the pathogenic potential of their interaction in order to aid in the design of novel strategies for the prevention and treatment of catheter-related UTIs.
Assuntos
Candida albicans/fisiologia , Contaminação de Equipamentos , Pseudomonas aeruginosa/fisiologia , Cateterismo Urinário/instrumentação , Aderência Bacteriana , Humanos , Microscopia Eletrônica de VarreduraRESUMO
Se investigó la interacción entre aislamientos clínicos de Pseudomonasaeruginosa y Candida albicans, y su capacidad de adhesión in vitro encatéteres urinarios. Fue realizado análisis cuantitativo a través del cómputo deunidades formadoras de colonias y microscopía electrónica de barrido.Los resultados mostraron que el desarrollo de P. aeruginosa sobre catéteresurinarios fue mayor con la presencia de C. albicans, mientras que la presenciade la levadura no fue afectada significativamente. Son necesarios másestudios para comprender mejor la patogénesis de estos microorganismos ypara establecer estrategias para el control y el tratamiento de las infeccionesurinarias vinculadas al uso de catéteres(AU)
In this study, the in vitro adherence capabilities of Pseudomonas aeruginosaand Candida albicans clinical isolates to urinary catheters were investigated.Quantitative analysis was performed by colony-forming unit counts andscanning electron microscopy. Results demonstrated that the adherence ofP. aeruginosa to urinary catheters was enhanced in the presence ofC. albicans, while C. albicans adherence was not significantly affected.Further investigations are warranted to fully understand the pathogenicpotential of their interaction in order to aid in the design of novel strategies forthe prevention and treatment of catheter-related UTIs(AU)