Synthesis and Structure of a Copper-Based Functional Network for Efficient Organic Dye Adsorption.

In the work, by incorporating polyoxometalates (POMs) into a copper(II)-based network, a novel three-dimensional (3D) porous framework, [Cu17Cl3(trz)12]H3[GaW12O40]·9H2O (Cu-GaW-TRZ), was successfully prepared and explored for the adsorption of dyes. The adsorption capacity of Cu-GaW-TRZ was calculated as 13.11 mg/g, and the dye adsorption rate equaled 96.2% for the adsorption of methylene blue (MB). Furthermore, this recyclable adsorbent is stable enough without obvious loss of adsorption capacity for at least five runs. Meanwhile, the structure of the macropores is suitable for the entry of large molecular dyes, and [GaW12O40]5- also can achieve efficient adsorption for cationic dyes. The results displayed a pseudo-second-order kinetic model and were well matched for MB adsorption onto Cu-GaW-TRZ. The free energy, entropy, and enthalpy of the thermodynamic parameters for the adsorption of MB were calculated, which revealed that the adsorption process was befitting for the adsorption of MB.

The Combined Clinical Efficacy and Safety Analysis of Adoptive Immunotherapy with Radiotherapy and Chemotherapy in Non-Small-Cell Lung Cancer: Systematic Review and Meta-Analysis.

Objective: To explore the differential efficacy of chemoradiotherapy combined with adoptive immunotherapy and radiochemotherapy alone in patients with non-small-cell lung cancer (NSCLC). Methods: Qualified randomized controlled trial (randomized controlled trial, RCT), or nonrandomized concurrent controlled trial (NRCCT), published in various databases, including PubMed, EMBASE, Chinese journal full-text database, Medline, Cochrane database, and VIP Chinese database, and the Revman5. 0 software performed the data analysis. Results: We found the significantly different curative effect between the experimental and control groups (OR = 1.94, 95% CI (1.46, 2.58), P < 0.001, I 2 = 0%, Z = 4.59), effect of adoptive immunotherapy on the progression of disease (OR = 1.80, 95% CI (1.38, 2.35), P < 0.001, I 2 = 0%, Z = 4.33), adoptive immunotherapy on overall survival (OR = 2.19, 95% CI (1.60, 2.99), P < 0.001, I 2 = 0%, Z = 4.91), and adverse effects of adoptive immunotherapy (OR = 1.76, 95% CI (1.25, 2.48), P = 0.001, I 2 = 0%, Z = 3.26). Conclusion: Adoptive immunotherapy combined with microradiotherapy can decrease the recurrence of NSCLC and improve patient survival, as well as early patients can be benefited more significantly from immunotherapy.

Lung cancer with nephrotic syndrome as a paraneoplastic syndrome: A case report.

Paraneoplastic syndromes are immune disorders associated with clinical signs and symptoms caused by substances produced by malignant diseases and are not directly associated with a primary or metastatic tumour. The symptoms are the effects of hormones, immune cross-reactivity or cytokines. Paraneoplastic nephrotic syndrome (PNS) is often associated with membranous nephropathy (MN) in elderly patients with solid tumours, and there is continued debate regarding whether corticosteroids or immunosuppressants should be combined with cancer therapy for the syndrome. The present report describes a male patient with lung cancer associated with secondary MN who achieved remission under radiotherapy, with no use of corticosteroids or immunosuppressants. This case is rare. Therefore, when treating PNS related to lung cancer, more attention should be paid to the treatment of the cancer.

[Analysis on human papillomavirus 16 and 18 types infection among 805 patients with common anorectal lesions].

OBJECTIVE: To analyze the infection condition of human papillomavirus (HPV) type 16 and 18 in the squamous cells and columnar cells of patients with common anorecatal lesions. METHODS: Infections of HPV type 16 and 18 were determined with real-time fluorescent quantitative PCR in the wax-embedded surgical specimen of 805 patients with common anorectal diseases. RESULTS: The overall infection rate among 805 patients with anorecatal lesions was 66.1% (532/805). The infection rate was 82.6% (95/115) in patients with mixed hemorrhoids, 76.5% (88/115) in anal papillary fibromas, 74.8% (86/115) in internal hemorrhoids, 72.2% (83/115) in fistulas, 69.6% (80/115) in external hemorrhoids, 47.8% (55/115) in anal perianal abscesses, and 39.1% (45/115) in anal fissures. CONCLUSION: Infection rate of HPV type 16, 18 in common anorectal lesions is high.

[Survival analysis and prognosis of lung cancer related factors].

AIM: of non-small cell lung cancer (non a small eelllungeaneer, NSCLC) patients with survival analysis and prognostic factors. METHODS: The research I our hospital from 2005 to September 2010 on the treatment of 275 cases of clinical data of patients with NSCLC, and its age, pathological type, clinical stage, lymph node micrometastasis on prognosis and treatment Investigation of influence, and to analyze the prognostic factors for patients. RESULTS: The patients in the family history, clinical stage and other factors after treatment for patients with poor prognostic factors after treatment for patients with poor prognostic factors for survival. The treatment of choice for the greatest impact factor. This group of patients selected surgery plus chemotherpy, chemotherapy + radiotherapy, chemotherapy and symptomatic treatment 4, in the survival rates of patients in the four groups was significantly different (P < 0.05). The patients age, clinical stage, lymph node micrometastasis in pathological type on the prognosis of patients was statistically significant. CONCLUSION: The treatment of non-small cell lung cancer is an important prognostic factor.

[Feasibility of sewage sludge used as filling material in permeable reactive barrier].

Permeable reactive barriers (PRB) have been used widely as an alternative technique to treatment of acid mine drainage (AMD). Selection of the appropriate filling materials is the most important procedure to application of this treatment. Batch adsorption tests and bacteria culture batch tests were conducted to assess the possibility of sewage sludge served as filling material for PRB. Results from batch adsorption tests showed that the maximum adsorption capacities of the sewage sludge were 13.62 mg x g(-1) (Zn2+) and 15.60 mg x g(-1) (Cd2+). Bacteria culture batch tests indicated that SO4(2-) concentrations in reactors decreased from initial concentrations of 700 mg x L(-1) to below 300 mg x L(-1). Sulfate removal efficiency ranged from 60% to 70%. Fe and heavy metals, including Zn and Cd, were removed completely in two reactors. This study suggested that sewage sludge is a suitable filling material for PRB.

[Oxidation buffer capacity of sewage sludge barrier for immobilization of heavy metals].

Benefit from the microbial activities especially the anaerobic sulfate reduction processes, sewage sludge could be used as a barrier to immobilize the heavy metals leached from tailings. With respect to the redox reaction between sewage sludge and acid mine drainage (AMD), oxidation titration test was carried out to study the effect of oxidation buffer capacity (OBC) of sewage sludge on the immobilization of heavy metals. Test results showed that OBC of sludge suspensions was decreased slightly with the solid-liquid ratio of the suspensions, but increased with the anaerobic incubation time, and that more than 50% of OBC was contributed by the sludge existed in strongly-reduction conditions (Eh < or = - 150 mV). During oxidation titration test, Zn was released obviously when Eh > or = - 150 mV, while Cu and Pb released obviously when Eh > or = 150 mV. According to the test results, a mathematical model was established to predict the OBC consumption of the sludge barrier under AMD penetrating conditions. The simulation results showed that a sludge barrier with 2m thickness, even undergone 38 787-years oxidation by AMD under 10m water head, keep in a strongly-reduced condition and, therefore, promote an immobilization of heavy metals from AMD in the barrier.

[Acid buffer capacity of sewage sludge barrier for immobilization of heavy metals].

Employing the anaerobic activities of microorganisms, sewage sludge can be used as a barrier to immobilize the heavy metals leached from tailings. Due to the interactions between sewage sludge barrier and acid mine drainage (AMD), it is possible that the heavy metals that have been immobilized previously might be released out. The acid buffering capacity (ABC) of sewage sludge suspensions with various anaerobic incubation time and the effect of ABC on the mobility of heavy metals were investigated by acid titration tests. Test results showed that ABC of sewage sludge suspensions was increased with the solid-liquid ratio of the suspensions and the anaerobic incubation time, and that carbonate and organics play an important role in acid buffer of sewage sludge suspensions. During the acid titration test, Zn, Pb and Cu were released out obviously following the order of Zn > Cu > Pb as pH was decreased less than 6.2. A mathematical model was established to predict the ABC consumption of the sewage sludge barrier under AMD penetration condition. The simulation results showed that a sewage sludge barrier with 2.0 m thickness, even undergoing 666-years acidification by AMD under 10.0 m water head, can maintain a condition of pH > or = 6.2 and, therefore, keep immobilize the heavy metals of AMD in the barrier.