The Lemierre syndrome: suppurative thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection.

We present 2 cases of the Lemierre syndrome (also called postanginal septicemia), along with 36 other cases from a review of recent literature. A review of the literature during the preantibiotic era is also included. This disease is caused by an acute oropharyngeal infection with secondary thrombophlebitis of the internal jugular vein complicated by multiple metastatic infection. The majority of cases are caused by anaerobic gram-negative organisms, most frequently Fusobacterium necrophorum. An enhanced computed tomographic scan of the neck is the technique of choice to demonstrate the thrombosis of the internal jugular vein. Prolonged intravenous administration of antimicrobial agents known to have a good antianaerobic coverage, along with drainage of purulent collections, will usually be successful in the overwhelming majority of patients.

Occurrence of two cases of cryptococcosis within 3 months on the same general medical ward.

Two cases of systemic cryptococcal infection occurred on the same general medical ward within 3 months. The patients had been on the same ward for 5 days. Both had other diseases associated with depression of cellular immune responses had received immunosuppressive drugs.

A retrospective study of dermatophyte infection in Newfoundland for the period 1962-1968.

The results of a survey of dermatophyte infection in New-foundland for the period 1962 to 1968 are presented. A steady annual rise in the number of specimen submissions is noted, with positive findings in an average of 21.7%. The contribution by source of specimens is recorded, and species distribution indicates that Microsporum canis has behaved in epidemic form whereas other species appear endemic. Trichophyton rubrum infection shows a steady annual increase. No cases of favus have been noted. The distribution of species by anatomical site is indicated.