RESUMO
Lymph node metastases in cervical and endometrial cancer are major prognostic factors. Lymph-nodal involvement determines adjuvant therapy. As imagery is not reliable to diagnose lymph node status, pelvic +/- para-aortic lymphadenectomy remains the gold standard. These surgical procedures are, however, responsible for specific morbidity: lymphocele and lymphedema. Sentinel lymph node procedure could avoid lymphadenectomy and their complications in cervical and endometrial cancer with good negative predictive values. We present actual indications, procedure and results of sentinel lymph node procedures in cervical and endometrial cancer.
Assuntos
Adenocarcinoma/diagnóstico , Carcinoma de Células Escamosas/diagnóstico , Neoplasias do Endométrio/diagnóstico , Biópsia de Linfonodo Sentinela/efeitos adversos , Neoplasias do Colo do Útero/diagnóstico , Adenocarcinoma/cirurgia , Carcinoma de Células Escamosas/cirurgia , Neoplasias do Endométrio/cirurgia , Feminino , Humanos , Metástase Linfática , Linfedema/etiologia , Linfocele/etiologia , Estadiamento de Neoplasias/métodos , Prognóstico , Neoplasias do Colo do Útero/cirurgiaRESUMO
The aim of our research was to look for specific malaria antibodies in a randomized sample of 1.500 blood donors. We used the indirect immunofluorescence technique. During this project we have noticed the lack of validity of the "the five years rule" usually followed in France to prevent transfusion malaria. We have also evaluated the help brought by an "oriented investigation" allowing firstly a selection of potentially dangerous donors, secondly, the use of their blood bottles according to serology results. This work finally shows that total security can only be achieved by systematic research on all blood donors.