RESUMO
The importance of hemostasis investigations for present-day theoretical and clinical medicine is explained by the high incidence of thromboembolism which in recent years has noticeably increased in many countries of the world. Hemostasis is a physiological system that largely determines adaptability of man to the varying environment. The system may play a critical part in the sense that its disorders may cause severe complications. The mismatch of the system can be exemplified by the thrombohemorrhagic syndrome (THS) or disseminated intravascular coagulation of blood (DIC). Thrombogenesis or thromboembolism may strongly affect many physiological functions, particularly those of the cardiovascular and nervous systems. The process of thrombogenesis may also contribute significantly to atherosclerosis and should therefore be regarded as the leading factor in sudden and rapidly developing blood-vessel occlusion. Various aspects of blood coagulation are very important for the flying personnel exposed to many stress-effects in unusual and sometimes alien environments, e.g. hypoxia, acceleration, vibration, meteorological and climatic variations. In view of this, hemostasis maintenance as well as improved prophylaxis and treatment of thrombogenesis and atherosclerosis requires special attention.