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2.
Sleep Med Rev ; 62: 101609, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-35286895

RESUMO

Spontaneous resolution of pediatric obstructive sleep apnea (OSA) may stand behind the observed benefit of rapid maxillary expansion (RME), mainly supported by uncontrolled case series. We aimed to review the controlled, ideally randomized, evidence on the effectiveness of RME as compared to watchful waiting or alternative treatment of pediatric OSA. We only found one randomized clinical trial comparing RME with watchful waiting. The other four studies compared RME with the gold-standard treatment adenotonsillectomy, three of them in a non-randomized fashion. The results of the RCT showed no statistically significant differences in the enhancement of main (apnea hypopnea index, AHI) and secondary outcomes between RME and watchful waiting. Furthermore, reproducibility of the published studies was limited by insufficient description of their patients' inclusion criteria. We could not find convincing evidence of the benefit of RME over watchful waiting in patients with pediatric OSA. RCTs with reproducible inclusion criteria comparing RME with watchful waiting are still critically needed to support this intervention for the treatment of pediatric OSA. In the absence of solid evidence with RCT, RME should not be recommended for the treatment of pediatric OSA. PROSPERO REGISTRATION NUMBER: CRD42021249261. RUNNING SUMMARY: This systematic review explores the benefits of rapid maxillary expansion compared to spontaneous resolution of pediatric obstructive sleep apnea.


Assuntos
Técnica de Expansão Palatina , Apneia Obstrutiva do Sono , Adenoidectomia/métodos , Criança , Humanos , Ensaios Clínicos Controlados Aleatórios como Assunto , Reprodutibilidade dos Testes , Conduta Expectante
3.
Trauma Case Rep ; 23: 100226, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31372486

RESUMO

Lingual hematoma (LH) is an uncommon and potentially life-threatening condition due to its tendency to cause upper airway obstruction. It usually occurs as a result of trauma (motor vehicle accidents, grand mal seizures or traumatic tracheal intubations) and rarely spontaneously in cases of patients with inherited or acquired coagulopathies, high blood pressure, hematological disorders, or vascular malformations. Herein, we report the first case, to our knowledge, of a traumatic massive lingual hematoma in a patient with Systemic lupus erythematosus (SLE) secondary to tongue biting after neurological deterioration, hypertensive crisis and multiple tonic clonic seizures during hemodialysis for chronic renal failure.

4.
Asian J Androl ; 19(3): 303-310, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-26763546

RESUMO

Erectile dysfunction (ED) is considered a condition with a broad range of etiologies. Obstructive sleep apnea (OSA) syndrome is one of the lesser studied risk factors for ED. We intend to summarize the current evidence on the relationship between OSA and sexual impairment, focusing on the results in terms of erectile function of the different therapies offered to OSA patients. A systematic review was conducted, selecting articles related to the physiology of OSA and ED, and to the treatments of OSA syndrome and their reported outcomes in erectile and sexual function. Higher prevalences of ED in the OSA groups have been published. However, whether this effect on the erectile function occurs in the entire range of OSA severities remains unclear. Several hypotheses were proposed to explain the physiology of this association. Continuous Positive Airway Pressure as a treatment for OSA patients with ED has achieved a significative improvement in the sexual parameters in most of the studies. Phosphodiesterase type 5 inhibitors (iPDE5) on demand are useful as a treatment for ED in this subgroup of patients, with high satisfaction rates. The surgical treatment for the OSA evidenced benefits over the erectile function, and the effect on the sexual satisfaction of the therapy using Mandibular Advancement Devices is still undefined.


Assuntos
Disfunção Erétil/etiologia , Apneia Obstrutiva do Sono/complicações , Apneia Obstrutiva do Sono/terapia , Disfunção Erétil/tratamento farmacológico , Disfunção Erétil/epidemiologia , Humanos , Incidência , Masculino , Inibidores da Fosfodiesterase 5/uso terapêutico , Fatores de Risco , Apneia Obstrutiva do Sono/epidemiologia
5.
Chest ; 150(2): e59-64, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-27502995

RESUMO

A 51-year-old woman with a personal history of vitiligo, normal thyroid hormone studies, a simple hysterectomy for multiple uterine myomas at age 35 years, and childhood adenotonsillectomy was seen for progressive hearing loss. She reported mild asthenia, cold intolerance, mild dysphagia with frequent choking while eating and drinking, and a progressive increase in inspiratory effort, especially in the supine position. Her partner described a progressively worsening history of snoring and witnessed apneic episodes, mostly in the supine position. Mild to moderate daytime sleepiness was also present.


Assuntos
Bócio Nodular/complicações , Hipertireoidismo/etiologia , Tireoide Lingual/complicações , Apneia Obstrutiva do Sono/etiologia , Antitireóideos/uso terapêutico , Feminino , Bócio Nodular/diagnóstico por imagem , Bócio Nodular/cirurgia , Perda Auditiva/etiologia , Humanos , Hipertireoidismo/diagnóstico , Hipertireoidismo/tratamento farmacológico , Tireoide Lingual/diagnóstico por imagem , Tireoide Lingual/cirurgia , Imageamento por Ressonância Magnética , Metimazol/uso terapêutico , Pessoa de Meia-Idade , Cintilografia , Compostos Radiofarmacêuticos , Apneia Obstrutiva do Sono/cirurgia , Pertecnetato Tc 99m de Sódio , Decúbito Dorsal , Tomografia Computadorizada por Raios X
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