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1.
Torture ; 30(1): 66-78, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32657772

RESUMO

Conversion therapy is a set of practices that aim to change or alter an individual's sexual orientation or gender identity. It is premised on a belief that an individual's sexual orientation or gender identity can be changed and that doing so is a desirable outcome for the individual, family, or community. Other terms used to describe this practice include sexual orientation change effort (SOCE), reparative therapy, reintegrative therapy, reorientation therapy, ex-gay therapy, and gay cure. Conversion therapy is practiced in every region of the world. We have identified sources confirming or indicating that conversion therapy is performed in over 60 countries. In those countries where it is performed, a wide and variable range of practices are believed to create change in an individual's sexual orientation or gender identity. Some examples of these include: talk therapy or psychotherapy (e.g., exploring life events to identify the cause); group therapy; medication (including anti-psychotics, anti- depressants, anti-anxiety, and psychoactive drugs, and hormone injections); Eye Movement Desensitization and Reprocessing (where an individual focuses on a traumatic memory while simultaneously experiencing bilateral stimulation); electroshock or electroconvulsive therapy (ECT) (where electrodes are attached to the head and electric current is passed between them to induce seizure); aversive treatments (including electric shock to the hands and/or genitals or nausea-inducing medication administered with presentation of homoerotic stimuli); exorcism or ritual cleansing (e.g., beating the individual with a broomstick while reading holy verses or burning the individual's head, back, and palms); force-feeding or food deprivation; forced nudity; behavioural conditioning (e.g., being forced to dress or walk in a particular way); isolation (sometimes for long periods of time, which may include solitary confinement or being kept from interacting with the outside world); verbal abuse; humiliation; hypnosis; hospital confinement; beatings; and "corrective" rape. Conversion therapy appears to be performed widely by health professionals, including medical doctors, psychiatrists, psychologists, sexologists, and therapists. It is also conducted by spiritual leaders, religious practitioners, traditional healers, and community or family members. Conversion therapy is undertaken both in contexts under state control, e.g., hospitals, schools, and juvenile detention facilities, as well as in private settings like homes, religious institutions, or youth camps and retreats. In some countries, conversion therapy is imposed by the order or instructions of public officials, judges, or the police. The practice is undertaken with both adults and minors who may be lesbian, gay, bisexual, trans, or gender diverse. Parents are also known to send their children back to their country of origin to receive it. The practice supports the belief that non-heterosexual orientations are deviations from the norm, reflecting a disease, disorder, or sin. The practitioner conveys the message that heterosexuality is the normal and healthy sexual orientation and gender identity. The purpose of this medico-legal statement is to provide legal experts, adjudicators, health care professionals, and policy makers, among others, with an understanding of: 1) the lack of medical and scientific validity of conversion therapy; 2) the likely physical and psychological consequences of undergoing conversion therapy; and 3) whether, based on these effects, conversion therapy constitutes cruel, inhuman, or degrading treatment or torture when individuals are subjected to it forcibly2 or without their consent. This medico-legal statement also addresses the responsibility of states in regulating this practice, the ethical implications of offering or performing it, and the role that health professionals and medical and mental health organisations should play with regards to this practice. Definitions of conversion therapy vary. Some include any attempt to change, suppress, or divert an individual's sexual orientation, gender identity, or gender expression. This medico-legal statement only addresses those practices that practitioners believe can effect a genuine change in an individual's sexual orientation or gender identity. Acts of physical and psychological violence or discrimination that aim solely to inflict pain and suffering or punish individuals due to their sexual orientation or gender identity, are not addressed, but are wholly condemned. This medico-legal statement follows along the lines of our previous publications on Anal Examinations in Cases of Alleged Homosexuality1 and on Forced Virginity Testing.2 In those statements, we opposed attempts to minimise the severity of physical and psychological pain and suffering caused by these examinations by qualifying them as medical in nature. There is no medical justification for inflicting on individuals torture or other cruel, inhuman, or degrading treatment or punishment. In addition, these statements reaffirmed that health professionals should take no role in attempting to control sexuality and knowingly or unknowingly supporting state-sponsored policing and punishing of individuals based on their sexual orientation or gender identity.


Assuntos
Terapia Aversiva/métodos , Identidade de Gênero , Punição , Comportamento Sexual , Tortura , Fármacos do Sistema Nervoso Central , Consenso , Eletroconvulsoterapia , Feminino , Humanos , Masculino , Psicoterapia
2.
Ceylon Med J ; 65(4): 112-117, 2020 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-34825559

RESUMO

BACKGROUND: Arishta have been used in Ayurveda medicine for over thousands of years in Sri Lanka to treat various diseases. Ashwagandharishta, Balarishta and Dashamoolarishta are usually prescribed to obtain an anabolic effect, and Ashwagandharishta and Dashamoolarishta for androgenic effect in males. Thus, these arishta have been shown to have similar effect as anabolic androgenic steroids and stimulants in Western medicine. Therefore, arishta could potentially be used by athletes to improve their performance in sports leading to unintentional doping. Additionally, ethanol develops in-source during arista fermentation, which can affect athletes health. OBJECTIVE: The aim of this study is to investigate whether the anabolic androgenic steroids or stimulants banned by World Anti-Doping Agency are present in these arishta, and to determine their ethanol content. METHODS: Methanol extractions of Ashwagandarishta, Balarishta, Dashamoolarishta from four different manufacturers were screened for 21 stimulant and 22 anabolic androgenic steroids banned by World Anti-Doping Agency, using Gas Chromatography Mass Spectrometer. Ethanol content of the twelve Arishta samples were also measured. RESULTS: Anabolic androgenic steroids or stimulants were not present in the tested Arishta samples, and percentage volume / volume ethanol content of all Arishta was between (5.80-8.35) ±0.5. CONCLUSION: The tested brands of Ashwagandharishta, Balarishta and Dashamoolarishta did not contain stimulants or anabolic androgenic steroids banned by World Anti-Doping Agency.


Assuntos
Dopagem Esportivo , Substâncias para Melhoria do Desempenho , Etanol , Humanos , Masculino , Sri Lanka , Esteroides
3.
Ceylon Med J ; 64(3): 103-110, 2019 Sep 30.
Artigo em Inglês | MEDLINE | ID: mdl-32120460

RESUMO

Introduction: Sri Lanka has a predominantly rural population. However, there is a dearth of research on health and socioeconomic issues in this group. Objective: To describe basic socioeconomic characteristics and health profile in a rural population. Methods: A descriptive cross-sectional household survey was conducted in 1950 households in three rural districts, selected by a three-stage stratified cluster sampling method. Results: The population pyramid showed an ageing population (dependency ratio of 50%). Only 39% had completed GCE (ordinary level). Unemployment rates were high (25% males, 76% females). Agriculture and related work were main occupations. Most lacked amenities (e.g. 61% households lacked a refrigerator) and practiced inappropriate methods of waste disposal (e.g. open burning by 72%). Household illnesses were frequent: episodes of acute illness within two weeks, injuries within past year and chronic illness were reported from 35.9%, 14.9% and 48.3% households. The prevalence of chronic diseases in adults >20 years were high: diabetes 13.5%, hypertension 16.7% and overweight/obesity 28.2%. Of the males, 22.1% smoked and 12.3% took alcohol. Almost 25% adults chewed betel. Reports of snake bite, dog bites and suicide/attempted suicide were seen in 15.5%, 9.7% and 3.0% households respectively. Conclusions: This study shows a unique clustering of health-related problems in rural Sri Lanka. This was characterized by demographic transition, burden from snake bites, chronic diseases and acute illnesses. There were resource limitations and low levels of education. Cohort studies and comparisons with urban areas will enable further elucidation of determinants of health and other issues in rural Sri Lanka.


Assuntos
Doença Aguda/epidemiologia , Doença Crônica/epidemiologia , Características da Família , População Rural/estatística & dados numéricos , Fatores Socioeconômicos , Análise por Conglomerados , Estudos Transversais , Feminino , Inquéritos Epidemiológicos , Humanos , Masculino , Mordeduras de Serpentes/epidemiologia , Sri Lanka/epidemiologia , Desemprego/estatística & dados numéricos
4.
Heart Surg Forum ; 18(4): E167-70, 2015 Aug 30.
Artigo em Inglês | MEDLINE | ID: mdl-26334855

RESUMO

A 43-year-old male, with no previous history of mental illness, was diagnosed with coronary heart disease, after which he became acutely depressed and attempted suicide by ingesting an organophosphate pesticide. He was admitted to an intensive care unit and treated with pralidoxime, atropine, and oxygen. His coronary occlusion pattern required early coronary artery bypass grafting (CABG) surgery. His family, apprehensive of a repeat suicidal attempt, requested surgery be performed as soon as possible. He recovered well from the OP poisoning and was mentally fit to express informed consent 2 weeks after admission. Seventeen days after poisoning, he underwent coronary artery bypass grafting and recovered uneventfully. Six years later, he remains in excellent health. We report this case because to the best of our knowledge there is no literature regarding CABG performed soon after organophosphate poisoning.


Assuntos
Ponte de Artéria Coronária/métodos , Doença da Artéria Coronariana/complicações , Doença da Artéria Coronariana/cirurgia , Intoxicação por Organofosfatos/complicações , Intoxicação por Organofosfatos/terapia , Adulto , Doença da Artéria Coronariana/diagnóstico , Humanos , Masculino , Intoxicação por Organofosfatos/diagnóstico , Resultado do Tratamento
5.
J Occup Med Toxicol ; 10: 4, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25670963

RESUMO

BACKGROUND: Traffic policemen are identified to be at a higher risk of exposure to air pollution and its contaminants such as lead. A study done prior to the introduction of unleaded petroleum in Sri Lanka revealed a mean blood lead level of 53.07 µg/dL, which was well above the Center for Disease Control defined acceptable safe levels. This study aimed to determine whether unleading of fuel has made an impact on the blood lead levels of traffic police working in an urban area with high traffic density. METHOD: A cross-sectional survey of 168 traffic police personnel working within Colombo city limits of Sri Lanka, a high traffic density area, was conducted. Blood lead levels of participants were measured using nitric acid, perchloric acid ashing method and atomic absorption spectrophotometry. An interviewer administered questionnaire was used for a targeted history and examination. RESULTS AND DISCUSSION: Mean age of the sample population was 37 years. Thirty eight percent had detectable levels of lead in blood and 24.4% of the study sample had blood lead levels above Centre for disease control defined safe limits. Sample mean was 4.82 µg/dL (95% CI 3.58-6.04), and this is a 91% overall reduction when compared to data prior to unleading. Neither symptoms nor signs of classic lead toxicity showed significant correlation with toxic lead levels. CONCLUSION: Lead poisoning though still present in the high risk traffic warden population shows a considerable reduction following unleading. The need to have a low threshold to suspect lead poisoning is highlighted by the non-specific nature of the symptoms and signs of lead poisoning and its lack of association even in those found to have elevated lead levels. Further studies are required to elucidate a cause for the prevalence of lead poisoning despite cessation of using lead as an additive in petroleum.

7.
Health Policy Plan ; 30(1): 56-67, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24362640

RESUMO

BACKGROUND: Suicide in Sri Lanka is a major public health problem and in 1995 the country had one of the highest rates of suicide worldwide. Since then reductions in overall suicide rates have been largely attributed to efforts to regulate a range of pesticides. The evolution, context, events and implementation of the key policy decisions around regulation are examined. METHODS: This study was undertaken as part of a broader analysis of policy in two parts-an explanatory case study and stakeholder analysis. This article describes the explanatory case study that included an historical narrative and in-depth interviews. RESULTS: A timeline and chronology of policy actions and influence were derived from interview and document data. Fourteen key informants were interviewed and four distinct policy phases were identified. The early stages of pesticide regulation were dominated by political and economic considerations and strongly influenced by external factors. The second phase was marked by a period of local institution building, the engagement of local stakeholders, and expanded links between health and agriculture. During the third phase the problem of self-poisoning dominated the policy agenda and closer links between stakeholders, evidence and policymaking developed. The fourth and most recent phase was characterized by strong local capacity for policymaking, informed by evidence, developed in collaboration with a powerful network of stakeholders, including international researchers. CONCLUSIONS: The policy response to extremely high rates of suicide from intentional poisoning with pesticides shows a unique and successful example of policymaking to prevent suicide. It also highlights policy action taking place 'under the radar', thus avoiding policy inertia often associated with reforms in lower and middle income countries.


Assuntos
Praguicidas/intoxicação , Formulação de Políticas , Prevenção do Suicídio , Pessoal Administrativo , Agricultura/legislação & jurisprudência , Humanos , Entrevistas como Assunto , Política , Sri Lanka/epidemiologia , Suicídio/estatística & dados numéricos
8.
BMC Public Health ; 14: 839, 2014 Aug 13.
Artigo em Inglês | MEDLINE | ID: mdl-25118074

RESUMO

BACKGROUND: Sri Lanka has experienced major changes in its suicide rates since the 1970s, and in 1995 it had one of the highest rates in the world. Subsequent reductions in Sri Lanka's suicide rates have been attributed to the introduction of restrictions on the availability of highly toxic pesticides. We investigate these changes in suicide rates in relation to age, gender, method specific trends and birth-cohort and period effects, with the aim of informing preventative strategies. METHODS: Secular trends of suicide in relation to age, sex, method, birth-cohort and period effects were investigated graphically using police data (1975-2012). Poisoning case-fatality was investigated using national hospital admission data (2004-2010). RESULTS: There were marked changes to the age-, gender- and method-specific incidence of suicide over the study period. Year on year declines in rates began in 17-25 year olds in the early 1980s. Reduction in older age groups followed and falls in all age groups occurred after all class I (the most toxic) pesticides were banned. Distinct changes in the age/gender pattern of suicide are observed: in the 1980s suicide rates were highest in 21-35 year old men; by the 2000s, this pattern had reversed with a stepwise increase in male rates with increasing age. Throughout the study period female rates were highest in 17-25 year olds. There has been a rise in suicide by hanging, though this rise is relatively small in relation to the marked decline in self-poisoning deaths. The patterns of suicides are more consistent with a period rather than birth-cohort effect. CONCLUSIONS: The epidemiology of suicide in Sri Lanka has changed noticeably in the last 30 years. The introduction of pesticide regulations in Sri Lanka coincides with a reduction in suicide rates, with evidence of limited method substitution.


Assuntos
Suicídio/estatística & dados numéricos , Adolescente , Adulto , Idoso , Criança , Estudos de Coortes , Feminino , Hospitalização/estatística & dados numéricos , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Polícia , Sri Lanka/epidemiologia , Suicídio/tendências
9.
Crisis ; 35(2): 90-101, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24491824

RESUMO

BACKGROUND: Suicide is and has been a major public health problem in Sri Lanka and has generated a wide range of literature. AIMS: This review aimed to systematically appraise what is known about suicide in Sri Lanka. The patterns and content of articles were examined and recommendations for further research proposed. METHOD: The paper describes the systematic search, retrieval, and quality assessment of studies. Thematic analysis techniques were applied to the full text of the articles to explore the range and extent of issues covered. RESULTS: Local authors generated a large body of evidence of the problem in early studies. The importance of the method of suicide, suicidal intention, and the high incidence of suicide were identified as key foci for publications. Neglected areas have been policy and health service research, gender analysis, and contextual issues. CONCLUSION: The literature reviewed has produced a broad understanding of the clinical factors, size of the problem, and social aspects. However, there remains limited evidence of prevention, risk factors, health services, and policy. A wide range of solutions have been proposed, but only regulation of pesticides and improved medical management proved to be effective to date.


Assuntos
Política de Saúde , Pesquisa , Suicídio/estatística & dados numéricos , Feminino , Humanos , Incidência , Masculino , Fatores Sexuais , Sri Lanka/epidemiologia , Suicídio/psicologia , Tentativa de Suicídio/prevenção & controle , Tentativa de Suicídio/psicologia , Tentativa de Suicídio/estatística & dados numéricos , Prevenção do Suicídio
10.
Clin Toxicol (Phila) ; 49(1): 21-8, 2011 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21288148

RESUMO

INTRODUCTION: Deliberate self-harm with pesticides is a significant public health problem in rural Asia. We have previously shown an improved survival of patients with paraquat self-poisoning following the introduction of a new formulation with an increased emetic concentration, an alginate and a purgative in Sri Lanka. Further, formulation changes were introduced in October 2006; this study was designed to assess the impact of these changes on 6-week mortality following paraquat ingestion. METHODS: Prospective, cohort study of patients admitted with paraquat poisoning to 10 hospitals across Sri Lanka between September 2006 and September 2008. RESULTS: Overall, there was a significant (p < 0.001) increase in survival in the 533 patients included in this study compared to previous data (44.5 vs. 35.2% before September 2006 and 27.1% before October 2004). Patients ingesting the new INTEON formulation had a higher survival rate than those ingesting standard formulation (40.2 vs. 31.0%), but this effect was not statistically significant in Cox's proportional hazards model (hazard ratio 0.81, 95% CI 0.61?1.08 (unadjusted) and 1.17, 95% CI 0.82?1.68 (fully adjusted), respectively). CONCLUSIONS: This study has confirmed a continued improvement in survival of patients following self-harm with paraquat in Sri Lanka in recent years; however, in contrast to previous investigations, a beneficial effect associated with the INTEON formulation could not be substantiated. This may be partly due to the large number of patients in whom paraquat concentrations were too low for analytical confirmation of the formulation (n = 105) and who had a very high survival rate (86.7%).


Assuntos
Herbicidas/intoxicação , Paraquat/intoxicação , Adolescente , Adulto , Alginatos/administração & dosagem , Química Farmacêutica , Estudos de Coortes , Feminino , Ácido Glucurônico/administração & dosagem , Ácidos Hexurônicos/administração & dosagem , Humanos , Masculino , Pessoa de Meia-Idade , Paraquat/administração & dosagem , Estudos Prospectivos , Comportamento Autodestrutivo , Sri Lanka , Taxa de Sobrevida
11.
J Med Toxicol ; 6(1): 35-6, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-20229151

RESUMO

Diquat is a bipyridyl herbicide with nephrotoxic effects. This in vitro study demonstrates a colorimetric test for detection of diquat in human urine. Urine specimens using ten concentrations of diquat herbicide solution and controls for urine and glyphosate were prepared. A two-step assay (addition of bicarbonate followed by sodium dithionite) was performed, with a resulting color change of the original solution for each specimen. Color change intensity was noted immediately and after 30 min, by gross visual inspection. A green color with concentration-dependent intensity was detected in all specimens, in which concentrations of diquat solution ranged from 0.73 to 730 mg/L. This colorimetric effect disappeared after 30 min. The sodium bicarbonate/dithionite test may be useful as a qualitative bedside technique for the detection of urinary diquat in the appropriate clinical setting.


Assuntos
Colorimetria , Diquat/intoxicação , Diquat/urina , Herbicidas/intoxicação , Herbicidas/urina , Sistemas Automatizados de Assistência Junto ao Leito , Biomarcadores/urina , Ditionita/química , Humanos , Intoxicação/diagnóstico , Intoxicação/urina , Valor Preditivo dos Testes , Reprodutibilidade dos Testes , Bicarbonato de Sódio/química
12.
Med Sci Law ; 50(1): 25-8, 2010 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-20349691

RESUMO

INTRODUCTION: Deaths from suicide reached a peak in Sri Lanka in 1995. Several interventions reduced the suicide rate of 48.7 per 100,000 in 1995 to 23 per 100,000 in 2006, though it is still a major socioeconomic problem. All suicides have to be reported to the Inquirer of Sudden Death (ISD) or 'Coroner', according to the Criminal Procedure Code. METHOD: All deaths where a verdict of 'suicide' was given after an inquest at the Coroner's Court, Colombo, in 2006 were studied. Close relations or friends who attended the inquest were interviewed by medically qualified research assistants. Age, sex, marital and occupational status, level of education, living circumstances and method and reasons for the suicide were studied. RESULTS: During 2006, 151 deaths from suicide were documented, of which 93 (62%) were men. The majority (47%) were aged between 20 and 29 years. One-third of the victims was unemployed. At the time of committing suicide, 75% were living with family; 89 (59%) were married and 46 (31%) were single. Poisoning was the cause of death in 66 (44%), 48 (70%) of which were due to pesticides. Burns caused 51 (34%) deaths. Other common causes of death included hanging (11%), jumping in front of a train (7%) and drowning (3%). The commonest reason for suicide was dispute with the spouse/marital disharmony (30%). Other reasons were dispute with parents (8%), financial matters (7%), organic diseases (7%), alcoholism (7%), psychiatric illnesses (6%) and disputes in love affairs (5%). In 29 cases (19%), no definite reason for the suicide was evident. DISCUSSION: Self-poisoning and self-immolation were the commonest methods used to commit suicide. Marital disharmony was the main reason (30%). Psychiatric illnesses were responsible for only 6%. Future interventional activities should include secure access and restriction of the availability of pesticides and drugs, empowering people to manage anger and conflicts, and recognition and treatment of alcoholism and psychiatric illnesses. The success story of the reduction in the incidence of suicides in Sri Lanka should be a lesson to many developing countries where suicide is a major socioeconomic and health issue.


Assuntos
Suicídio/estatística & dados numéricos , Adolescente , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Médicos Legistas , Escolaridade , Emprego/estatística & dados numéricos , Feminino , Medicina Legal , Humanos , Masculino , Estado Civil/estatística & dados numéricos , Métodos , Pessoa de Meia-Idade , Ocupações/estatística & dados numéricos , Estudos Prospectivos , Distribuição por Sexo , Sri Lanka/epidemiologia , Adulto Jovem
13.
J Forensic Leg Med ; 16(8): 486-8, 2009 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-19782323

RESUMO

A family of six members were murdered at their own residence. Four of the family members had been killed with large heavy sharp weapons which produced multiple deep cut injuries predominantly on the neck and face. In these victims, death occurred as a result of haemorrhage. Two family members were killed by ligature strangulation and hanging. The victim, who was hanged, was sexually abused before she was killed. An unusual finding was the presence of an alleged assailant to the murders with multiple blunt weapon trauma to his body, at the scene of crime. The homicides of the family were as a result of personal disputes between the perpetrators who were their neighbours. Three of the alleged assailants were charged for murder and rape. The fourth assailant was charged for rape. No conclusive evidence as to who caused the death of the alleged perpetrator was reached.


Assuntos
Família , Homicídio , Adulto , Asfixia/patologia , Dissidências e Disputas , Feminino , Patologia Legal , Hemorragia/etiologia , Hemorragia/patologia , Humanos , Masculino , Métodos , Pessoa de Meia-Idade , Lesões do Pescoço/patologia , Estupro , Sri Lanka , Ferimentos Penetrantes/patologia
14.
Med Sci Law ; 48(4): 325-8, 2008 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-19051670

RESUMO

Sudden Infant Death Syndrome (SIDS), also known as 'unexplained deaths under one year', is rarely reported in Sri Lanka as a cause of post-neonatal mortality. The aim of this study was to assess the opinion of paediatricians and pathologists regarding the reasons for this rarity. Members of the Colleges of Paediatricians, Pathologists and Forensic Pathologists who met the inclusion criteria were selected as the study population. A brief self-administered questionnaire was used for data collection. Results were analysed using standard statistical methods. The sample consisted of 50 paediatricians, 15 histopathologists and seven forensic pathologists with a mean career span of 26.3 years. SIDS was reportedly diagnosed by only nine (12.5%) of the respondents while the other 63 (87.5%) have never encountered SIDS during their careers. Of the nine doctors, three (33.3%) based their diagnosis on autopsy findings but histological and toxicological studies had not been performed. The other six doctors (66.6%) relied on clinical history alone. Twenty-five doctors (34.7%) believed that keeping babies under close adult supervision was the reason SIDS is so rare in Sri Lanka. Twenty paediatricians (40%) and four histopathologists (26.7%) agreed with this view while five forensic pathologists (71.4%), believed the reason was under-diagnosis. In conclusion, the majority of doctors believe the most likely reason for the rarity of SIDS in Sri Lanka is that babies are kept under close adult supervision, in comparison with developed countries. By contrast, most forensic pathologists are of the opinion that SIDS is under-diagnosed.


Assuntos
Atitude do Pessoal de Saúde , Morte Súbita do Lactente/epidemiologia , Estudos Transversais , Humanos , Lactente , Sri Lanka/epidemiologia , Morte Súbita do Lactente/diagnóstico , Inquéritos e Questionários
15.
PLoS Med ; 5(2): e49, 2008 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-18303942

RESUMO

BACKGROUND: Pesticide ingestion is a common method of self-harm in the rural developing world. In an attempt to reduce the high case fatality seen with the herbicide paraquat, a novel formulation (INTEON) has been developed containing an increased emetic concentration, a purgative, and an alginate that forms a gel under the acid conditions of the stomach, potentially slowing the absorption of paraquat and giving the emetic more time to be effective. We compared the outcome of paraquat self-poisoning with the standard formulation against the new INTEON formulation following its introduction into Sri Lanka. METHODS AND FINDINGS: Clinical data were prospectively collected on 586 patients with paraquat ingestion presenting to nine large hospitals across Sri Lanka with survival to 3 mo as the primary outcome. The identity of the formulation ingested after October 2004 was confirmed by assay of blood or urine samples for a marker compound present in INTEON. The proportion of known survivors increased from 76/297 with the standard formulation to 103/289 with INTEON ingestion, and estimated 3-mo survival improved from 27.1% to 36.7% (difference 9.5%; 95% confidence interval [CI] 2.0%-17.1%; p = 0.002, log rank test). Cox proportional hazards regression analyses showed an approximately 2-fold reduction in toxicity for INTEON compared to standard formulation. A higher proportion of patients ingesting INTEON vomited within 15 min (38% with the original formulation to 55% with INTEON, p < 0.001). Median survival time increased from 2.3 d (95% CI 1.2-3.4 d) with the standard formulation to 6.9 d (95% CI 3.3-10.7 d) with INTEON ingestion (p = 0.002, log rank test); however, in patients who did not survive there was a comparatively smaller increase in median time to death from 0.9 d (interquartile range [IQR] 0.5-3.4) to 1.5 d (IQR 0.5-5.5); p = 0.02. CONCLUSIONS: The survey has shown that INTEON technology significantly reduces the mortality of patients following paraquat ingestion and increases survival time, most likely by reducing absorption.


Assuntos
Paraquat/química , Paraquat/intoxicação , Tentativa de Suicídio/tendências , Adolescente , Adulto , Química Farmacêutica , Feminino , Hospitalização/tendências , Humanos , Absorção Intestinal/efeitos dos fármacos , Absorção Intestinal/fisiologia , Masculino , Paraquat/administração & dosagem , Estudos Prospectivos , Sri Lanka/epidemiologia , Tentativa de Suicídio/prevenção & controle , Taxa de Sobrevida/tendências
16.
Torture ; 17(1): 53-6, 2007.
Artigo em Inglês | MEDLINE | ID: mdl-17456906

RESUMO

A retrospective study was performed to document the physical and psychological methods of torture and their sequelae on 90 victims of torture who attended the Family Rehabilitation Centres in Vavuniya, Trincomalee and Anuradhapura, using a standard assessment format. The study showed that the methods of torture practised in Sri Lanka are similar to that of other countries. The methods are physical and psychological. Being a victim of a traumatic event would be physically and psychologically stressful.


Assuntos
Tortura/estatística & dados numéricos , Adulto , Vítimas de Crime/psicologia , Vítimas de Crime/estatística & dados numéricos , Feminino , Humanos , Masculino , Métodos , Pessoa de Meia-Idade , Sri Lanka , Tortura/psicologia , Ferimentos e Lesões/epidemiologia
17.
Am J Forensic Med Pathol ; 24(4): 356-60, 2003 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-14634475

RESUMO

Reported is a case of an assault causing extensive blunt force injuries in which the clinical, radiologic, and postmortem findings were all consistent with death resulting from brain damage arising from the assault. The assailant was charged with murder. Subsequent full neuropathologic (including histologic) examination revealed the unsuspected finding of a widespread meningoencephalitis but no evidence of significant traumatic brain damage. The contributions of the infective process and of the trauma to death were felt to be unclear and a guilty plea to attempted murder was accepted. This case highlights the importance of a full neuropathologic examination, including histology, in cases of trauma to the head, even when the cause of death may initially appear obvious.


Assuntos
Meningoencefalite/patologia , Ferimentos não Penetrantes/patologia , Adulto , Encéfalo/patologia , Infarto Encefálico/patologia , Feminino , Proteína Glial Fibrilar Ácida/análise , Homicídio , Humanos , Leucócitos Mononucleares/patologia , Meninges/patologia
18.
Lancet ; 360(9340): 1163-7, 2002 Oct 12.
Artigo em Inglês | MEDLINE | ID: mdl-12387969

RESUMO

In parts of the developing world, pesticide poisoning causes more deaths than infectious diseases. Use of pesticides is poorly regulated and often dangerous; their easy availability also makes them a popular method of self-harm. In 1985, the UN Food and Agriculture Organisation (FAO) produced a voluntary code of conduct for the pesticide industry in an attempt to limit the harmful effects of pesticides. Unfortunately, a lack of adequate government resources in the developing world makes this code ineffective, and thousands of deaths continue today. WHO has recommended that access to highly toxic pesticides be restricted--where this has been done, suicide rates have fallen. Since an Essential Drugs List was established in 1977, use of a few essential drugs has rationalised drug use in many regions. An analogous Minimum Pesticides List would identify a restricted number of less dangerous pesticides to do specific tasks within an integrated pest management system. Use of safer pesticides should result in fewer deaths, just as the change from barbiturates to benzodiazepines has reduced the number of deaths from pharmaceutical self-poisoning.


Assuntos
Causas de Morte , Países em Desenvolvimento , Doenças Profissionais/induzido quimicamente , Praguicidas/intoxicação , Intoxicação/mortalidade , Suicídio/estatística & dados numéricos , Poluição Ambiental/prevenção & controle , Humanos , Doenças Profissionais/mortalidade , Doenças Profissionais/prevenção & controle , Praguicidas/classificação , Praguicidas/provisão & distribuição , Intoxicação/prevenção & controle , Risco , Prevenção do Suicídio
19.
J Toxicol Clin Toxicol ; 40(5): 551-5, 2002.
Artigo em Inglês | MEDLINE | ID: mdl-12215049

RESUMO

INTRODUCTION: Poisoning is a major health concern in Sri Lanka, which has a very high morbidity and mortality from pesticide poisoning. Poisoning, which continues to be in the first five leading causes of death, accounts for about 80,000 hospitalizations and over 3,000 deaths per year. The National Poisons Information Centre in Sri Lanka, thefirst such centre to be established in South Asia, completed 10 years service in 1997. The 4,070 calls received in thefirst 10 years are analyzed and compared with the national hospitalization pattern. METHODS: The recorded data sheets of all enquiries received from 1988 to 1997 were analyzed retrospectively to study (1) purpose of enquiry, (2) category of enquirer, (3) circumstances of poisoning, (4) gender of victim, (5) age of victim, (6) type of poison, and (7) outcome. Items (6) and (7) were compared with the national hospital statistics for 1998. RESULTS: Of the 4,070 enquiries, 92% concerned specific patients and 6% were for information on poisons. Almost 90% of the enquiries were from medical or paramedical personnel, 5% from relatives or friends, and 3% from the victims. Nearly 38% of enquiries concerned pesticides compared to 27% of poisoning hospitalizations. Medicinal agents were the subject of 20% of enquiries compared to 13% of hospitalizations. The major discrepancy was for snake bites, accounting for only 6% of enquiries but 42% of hospitalizations. Sex distribution of enquiries showed more males than females. Thirty-seven percent of the victims were young adults-15-29years age group. Nearly 49% of the enquiries were for suicidal attempts. Seventy-one percent of the victims recovered. CONCLUSIONS: Although enquiries to the NPIC averaged only 0.5% of poisoning hospitalizations, they were sufficiently representative of the national pattern to predict that increasing utilization of the NPIC would offer a much needed service, both for


Assuntos
Hospitalização/estatística & dados numéricos , Centros de Controle de Intoxicações/estatística & dados numéricos , Intoxicação/epidemiologia , Adolescente , Adulto , Idoso , Criança , Pré-Escolar , Feminino , Mortalidade Hospitalar , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Praguicidas/intoxicação , Intoxicação/mortalidade , Sri Lanka/epidemiologia , Tentativa de Suicídio/estatística & dados numéricos
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