Heart Rate Variability in Military Pilots During Flight: A Scoping Review.

INTRODUCTION: Piloting an aircraft is a complex multitasking activity that involves managing information in a nonautomatic way and generates a high workload (psychological, cognitive, and physical) for the pilot. The excess of these demands can result in decreased performance and may impair flight safety. Heart rate variability (HRV) has been used in recent studies as a method to investigate operator's workload in complex environments. This measure can assess the stress and recovery ability of the autonomic nervous system. However, a better understanding of flight influence on the pilot's autonomic modulation is necessary. Therefore, this scoping review aims to systematically map the studies related to changes in the autonomic modulation in military pilots during flight, in order to characterize their workload at different times and flight profiles. MATERIALS AND METHODS: A literature search was conducted using MEDLINE (by PubMed), SCOPUS, and LILACS databases. Recent records (2002-2022) that analyzed HRV in military pilots during flight were included. Meanwhile, studies in which piloting activity was not performed were excluded. The study was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline extension for Scoping Reviews and the Updated Methodological Guidance for the Conduct of Scoping Reviews. RESULTS: A total of 298 records were obtained, of which 19 were included in the scoping review. The studies analyzed flights performed in high- and low-performance aircrafts, helicopters, and flight simulators, using time domain, frequency domain, and nonlinear HRV indices. Real and simulated flights produced significant autonomic changes. Some flights elicited autonomic nervous system responses that persisted up to 5 h after landing. During real flight, the most sensitive indices for identifying variations in pilot workload were root mean square of successive differences between normal heartbeats, standard deviation of interbeat interval of normal sinus beat (SDNN), ratio of low-frequency to high-frequency power, and Poincaré plot standard deviation perpendicular to the line of identity (SD1), whereas the interbeat interval (RR), SDNN, SD1, and Poincaré plot standard deviation along the line of identity (SD2) were the most sensitive indices when comparing segments of simulated flight with different levels of difficulty. CONCLUSIONS: This scoping review provided insight into the influence of flight on autonomic modulation in military pilots. Some key themes were highlighted: Increased sympathetic activity during flight, sensibility of different domains of HRV to flight demands, and autonomic changes during recovery time. Future research efforts may allow us to enhance the understanding of pilot's workload limits and to elucidate the optimal postflight recovery time.

Prevalence of body composition phenotypes and their associations with glycemic, lipidic, and inflammatory biomarkers: a population-based study.

We aimed to verify the prevalence of body composition phenotypes and the association of glycemic, lipidic, and inflammatory biomarkers with such phenotypes. This is a cross-sectional, population-based study, with 720 participants aged 20 to 59 years. Body composition was assessed by dual-energy X-ray absorptiometry. Obesity was defined as body fat percentage ≥ 25% in males and ≥ 32% in females and sarcopenia by appendicular muscle mass index < 7.0kg/m2 in males and < 5.5kg/m2 in females. Sarcopenic obesity (SO) was defined as the presence of both sarcopenia and obesity. The prevalence of obesity, sarcopenia, and SO were 62.5%, 4.5%, and 6.2%, respectively. The association between biomarkers and phenotypes was verified using multinomial logistic regression models adjusted for confounding factors. The models showed that increased glycemia (OR = 3.39; 95%CI: 1.83-6.27), total cholesterol (TC) (OR = 2.24; 95%CI: 1.35-3.70), LDL-c (OR = 1.01; 95%CI: 1.00-1.02), VLDL-c (OR = 1.04; 95%CI: 1.02-1.06), non-HDL-c (OR = 1.02; 95%CI: 1.01-1.03), triglycerides (Tg) (OR = 3.66; 95%CI: 2.20-6.06), and decreased HDL-c (OR = 0.97; 95%CI: 0.95-0.98) were significantly associated with the obesity phenotype. Increased HOMA-IR (OR = 3.94; 95%CI: 1.69-9.21), LDL-c (OR = 1.01; 95%CI: 1.00-1.02), non-HDL-c (OR = 1.01; 95%CI: 1.00-1.02), and hs-CRP (OR = 2.42; 95%CI: 1.04-5.66) were independently associated with SO phenotype. Our findings indicate that increased glycemia, TC, Tg, LDL-c, VLDL-c, non-HDL-c, and decreased HDL-c may be indicators of the obesity phenotype and that increased hs-CRP, HOMA-IR, LDL-c, and non-HDL-c appear to be indicators of the SO phenotype. Those parameters may be used as additional markers for screening.

Prevalence of body composition phenotypes and their associations with glycemic, lipidic, and inflammatory biomarkers: a population-based study / Prevalência de fenótipos corporais e suas associações com biomarcadores dos perfis glicídico, lipídico e inflamatório: um estudo de base populacional / Prevalencia de fenotipos corporales y sus asociaciones con biomarcadores de perfiles glucídicos, lipídicos e inflamatorios: un estudio de base poblacional

Abstract: We aimed to verify the prevalence of body composition phenotypes and the association of glycemic, lipidic, and inflammatory biomarkers with such phenotypes. This is a cross-sectional, population-based study, with 720 participants aged 20 to 59 years. Body composition was assessed by dual-energy X-ray absorptiometry. Obesity was defined as body fat percentage ≥ 25% in males and ≥ 32% in females and sarcopenia by appendicular muscle mass index < 7.0kg/m2 in males and < 5.5kg/m2 in females. Sarcopenic obesity (SO) was defined as the presence of both sarcopenia and obesity. The prevalence of obesity, sarcopenia, and SO were 62.5%, 4.5%, and 6.2%, respectively. The association between biomarkers and phenotypes was verified using multinomial logistic regression models adjusted for confounding factors. The models showed that increased glycemia (OR = 3.39; 95%CI: 1.83-6.27), total cholesterol (TC) (OR = 2.24; 95%CI: 1.35-3.70), LDL-c (OR = 1.01; 95%CI: 1.00-1.02), VLDL-c (OR = 1.04; 95%CI: 1.02-1.06), non-HDL-c (OR = 1.02; 95%CI: 1.01-1.03), triglycerides (Tg) (OR = 3.66; 95%CI: 2.20-6.06), and decreased HDL-c (OR = 0.97; 95%CI: 0.95-0.98) were significantly associated with the obesity phenotype. Increased HOMA-IR (OR = 3.94; 95%CI: 1.69-9.21), LDL-c (OR = 1.01; 95%CI: 1.00-1.02), non-HDL-c (OR = 1.01; 95%CI: 1.00-1.02), and hs-CRP (OR = 2.42; 95%CI: 1.04-5.66) were independently associated with SO phenotype. Our findings indicate that increased glycemia, TC, Tg, LDL-c, VLDL-c, non-HDL-c, and decreased HDL-c may be indicators of the obesity phenotype and that increased hs-CRP, HOMA-IR, LDL-c, and non-HDL-c appear to be indicators of the SO phenotype. Those parameters may be used as additional markers for screening.

Resumo: Objetivou-se verificar a prevalência de fenótipos corporais e suas associações com biomarcadores dos perfis glicídico, lipídico e inflamatório. Trata-se de um estudo transversal, de base populacional, com 720 indivíduos de 20 a 59 anos. A composição corporal foi avaliada por absorciometria com raios X de dupla energia. Obesidade foi definida como percentual de gordura corporal ≥ 25% em homens e ≥ 32% em mulheres e sarcopenia pelo índice de massa muscular apendicular < 7,0kg/m2 em homens e < 5,5kg/m2 em mulheres. A obesidade sarcopênica foi definida como a coexistência de sarcopenia e obesidade. As prevalências de obesidade, sarcopenia e obesidade sarcopênica foram de 62,5%, 4,5% e 6,2%, respectivamente. A associação entre biomarcadores e fenótipos foi verificada por meio de modelos de regressão logística multinomial ajustados por variáveis de confusão. Os modelos mostraram que níveis aumentados de glicemia (OR = 3,39; IC95%: 1,83-6,27), colesterol total (OR = 2,24; IC95%: 1,35-3,70), LDL-c (OR = 1,01; IC95%: 1,00-1,02), VLDL-c (OR = 1,04; IC95%: 1,02-1,06), não HDL-c (OR = 1,02; IC95%: 1,01-1,03), triglicerídeos (OR = 3,66; IC95%: 2,20-6,06) e diminuição do HDL-c (OR = 0,97; IC95%: 0,95-0,98) foram significativamente associados ao fenótipo de obesidade. Índices aumentados de HOMA-IR (OR = 3,94; IC95%: 1,69-9,21), LDL-c (OR = 1,01; IC95%: 1,00-1,02), não HDL-c (OR = 1,01; IC95%: 1,00-1,02) e PCR-us (OR = 2,42; IC95%: 1,04-5,66) foram independentemente associados ao fenótipo de obesidade sarcopênica. Nossos resultados sugerem que níveis aumentados de glicemia, colesterol total, triglicerídeos, LDL-c, VLDL-c, não HDL-c e graus reduzidos de HDL-c são indicadores do fenótipo de obesidade e que o aumento em níveis de PCR-us, HOMA-IR, LDL-c e não HDL-c são indicadores do fenótipo de obesidade sarcopênica. Esses parâmetros podem ser usados como marcadores adicionais para triagem.

Resumen: El objetivo de este estudio fue evaluar la prevalencia de fenotipos corporales y sus asociaciones con biomarcadores de perfiles lipídicos, glucídicos e inflamatorios. Se trata de un estudio transversal, de base poblacional, realizado con 720 individuos de entre 20 y 59 años. La composición corporal se evaluó mediante absorciometría de rayos X de energía dual. La obesidad se estimó como porcentaje de grasa corporal ≥ 25% en hombres y ≥ 32% en mujeres, y la sarcopenia como índice de masa muscular apendicular < 7,0kg/m2 en hombres y < 5,5kg/m2 en mujeres. La obesidad sarcopénica se evaluó como la coexistencia de sarcopenia y obesidad. Las prevalencias de obesidad, sarcopenia y obesidad sarcopénica fueron del 62,5%, 4,5% y 6,2%, respectivamente. La asociación entre biomarcadores y fenotipos se comprobó mediante modelos de regresión logística multinomial ajustados por variables de confusión. Los modelos mostraron que el incremento de los niveles de glucosa en la sangre (OR = 3,39; IC95%: 1,83-6,27), colesterol total (OR = 2,24; IC95%: 1,35-3,70), LDL-c (OR = 1,01; IC95%: 1,00-1,02), VLDL-c (OR = 1,04; IC95%: 1,02-1,06), no HDL-c (OR = 1,02; IC95%: 1,01-1,03), triglicéridos (OR = 3,66; IC95%: 2,20-6,06) y disminución de HDL-c (OR = 0,97; IC95%: 0,95-0,98) se asociaron significativamente con el fenotipo de obesidad. Las tasas aumentadas de HOMA-IR (OR = 3,94; IC95%: 1,69-9,21), LDL-c (OR = 1,01; IC95%: 1,00-1,02), no-HDL-c (OR = 1,01; IC95%: 1,00-1,02) y PCR-us (OR = 2,42; IC95%: 1,04-5,66) se asociaron de manera independiente con el fenotipo de obesidad sarcopénica. Los resultados demuestran que el aumento de los niveles de glucosa en la sangre, colesterol total, triglicéridos, LDL-c, VLDL-c, no-HDL-c y grados reducidos de HDL-c son indicadores del fenotipo de obesidad y que el incremento de los niveles de PCR-us, HOMA-IR, LDL-c y no-HDL-c son indicadores del fenotipo de obesidad sarcopénica. Estos parámetros se pueden utilizar como marcadores adicionales para el cribado.

Neck circumference and its association with anthropometric, clinical, and biochemical parameters in patients with chronic kidney disease on hemodialysis / Circunferência do pescoço e sua associação com parâmetros antropométricos, clínicos e bioquímicos em pacientes com doença renal crônica em hemodiálise

ABSTRACT Objective: To investigate the association between neck circumference and anthropometric, clinical, and biochemical parameters in chronic kidney failure patients on hemodialysis. Methods: This is a cross-sectional study with patients with chronic kidney disease undergoing hemodialysis in Western Bahia. For the data collection, anthropometric measures were taken and clinical and biochemical data were gathered from the patient records and employing a structured questionnaire. A multiple linear regression was applied to evaluate the relationship between neck circumference and the anthropometric, clinical, and biochemical parameters. Results: A total of 119 patients were evaluated, of which 63.03% were men and 57.98% were aged between 35 and 59 years old. The mean neck circumference of the patients was 36.2±3.8 cm. A negative association was found between neck circumference and the female sex (p<0.001), while waist circumference (p<0.001), the body adiposity index (p=0.002), and pre-dialysis serum urea concentration (p=0.006) were positively associated with neck circumference. Conclusion: Neck circumference is inversely associated with the female sex and positively associated with a high waist circumference, body adiposity index, and serum urea concentration in patients with chronic kidney disease on hemodialysis.

RESUMO Objetivo: Investigar a associação entre circunferência do pescoço e parâmetros antropométricos, clínicos e bioquímicos em pacientes renais crônico sem hemodiálise. Métodos: Trata-se de um estudo transversal com pacientes com doença renal crônica em hemodiálise no Oeste da Bahia. Para a coleta de dados foram aferidas medidas antropométricas e dados clínicos e bioquímicos foram coletados dos prontuários dos pacientes e por meio de um questionário estruturado. A análise de regressão linear múltipla foi aplicada para avaliar a relação entre a circunferência do pescoço e os parâmetros antropométricos, clínicos e bioquímicos. Resultados: Foram avaliados 119 pacientes, sendo 63,03% homens e 57,98% com idade entre 35 e 59 anos. A média da circunferência do pescoço dos pacientes foi de 36,2±3,8 cm. Foi encontrada associação negativa entre a circunferência do pescoço e sexo feminino (p<0,001), enquanto a circunferência da cintura (p<0,001), o índice de adiposidade corporal (p=0,002) e a concentração sérica de ureia pré-diálise (p=0,006) foram positivamente associados à circunferência do pescoço. Conclusão: A circunferência do pescoço está inversamente associada ao sexo feminino e positivamente associada a uma circunferência abdominal elevada, índice de adiposidade corporal e concentração sérica de ureia em pacientes com doença renal crônica em hemodiálise.

The Visceral Adiposity Index Is a Better Predictor of Excess Visceral Fat in Military Pilots: A Cross-sectional Observational Study.

INTRODUCTION: Visceral adipose tissue (VAT) is related to cardiometabolic risk. Estimating it using the visceral adiposity index (VAI) could identify this risk in the Brazilian Air Force (BAF) aviator population. The aim here is to verify the predictive capacity of the VAI for identifying visceral fat areas compared to traditional obesity indicators in BAF pilots. MATERIALS AND METHODS: Forty male BAF pilots were recruited. The study was conducted in two stages: the first applied a structured questionnaire to characterize the sample and identify sedentary behavior and the second obtained nutritional, anthropometric, and body composition data, carrying out biochemical and magnetic resonance imaging tests and investigating physical activity level in this stage. The comparison of the predictive capacity of the VAI with that of other adiposity indicators (body mass index [BMI], waist circumference, waist-height ratio, waist-hip ratio, and neck circumference) for detecting increased VAT and the determination of the optimal cutoff points for the different adiposity indicators were carried out using receiving operating characteristic (ROC) curves. An association was verified between the adiposity indicators and excess visceral fat using Poisson regression analysis with robust variance. RESULTS: The VAI presented a better predictive capacity for VAT (area under the ROC curve = 0.941), while the BMI did not present diagnostic accuracy (95% CI < 0.5). The strength of the association with high visceral fat was also greater for the VAI than for the other indicators evaluated. CONCLUSIONS: The VAI was shown to be a better predictor of excess VAT in relation to the other indicators studied. As it is a more easy-access and lower-cost technique than resonance, it enables greater applicability in tracing and monitoring the visceral obesity of a large contingent of military personnel.

Prevalence of coronary risk factors in load transport drivers.

Introduction: Non-communicable diseases are the main cause of mortality worldwide, with risk factors that contribute to their development, including those associated with work activity. Objectives: To evaluate the prevalence of risk factors related to the development of non-communicable diseases and their relationship with work activity in professional load transport drivers. Methods: Eighty male truck drivers were assessed (39.73±10.91 years) with 15.22±12.09 years of professional experience. In addition to collection of anthropometric data and measurement of blood data, drivers answered three questionnaires: Physical Activity Readiness Questionnaire, Coronary Risk, and Finnish Diabetes Risk Score. Descriptive and inferential analyses were performed using Pearson correlation and Student's t test, considering a significance level of p < 0.05. Results: The results showed a prevalence of arterial hypertension of 31.30% and a medium coronary risk (46.30%), a factor that was directly associated with time of professional performance (r = 0.519; p < 0.05). Of the 80 truck drivers, 48.80% were physically inactive, 73.80% were overweight, and 7.50% had a high risk for the development of diabetes. Conclusions: The professional category studied presents an excess risk for health problems in the context of non-communicable diseases due to the peculiar characteristics of their profession.

Metabolically unhealthy and overweight phenotypes are associated with increased levels of inflammatory cytokines: a population-based study.

OBJECTIVE: The aim of this study was to determine the association between cytokine levels in metabolic phenotypes. Our hypothesis was that an unhealthy metabolic profile is associated to higher levels of proinflammatory cytokines. METHODS: The study sample was composed of 743 Brazilian adults classified in four phenotypes: metabolically healthy normal weight (MHNW), metabolically unhealthy normal weight (MUNW), metabolically healthy overweight (MHOW), and metabolically unhealthy overweight (MUOW). Sociodemographic, anthropometric, clinical, and biochemical parameters were collected. Six different cytokines were analyzed from blood samples using the CBA Human Inflammatory cytokines kit and the values divided in quartiles for analysis. Logistic regression models were constructed to assess the association between metabolic phenotypes and cytokines concentrations, adjusted for potential confounders and P < 0.05 was used. RESULTS: The MUOW phenotype showed a higher risk for increased levels of all cytokines analyzed compared with the reference group (MHNW). CONCLUSIONS: These results indicated that excess weight and altered metabolic profile are related to inflammation, especially when both conditions are associated, possibly linked to visceral adiposity. Therefore, the categorization of metabolic phenotypes in populations is an important factor for prevention of chronic diseases, as inflammation is associated with cardiovascular risk and obesity is not the only influencing factor.

Association between bone mineral content and dietary patterns among Brazilian adults from Viçosa, Minas Gerais: a population-based study / Associação entre conteúdo mineral ósseo e padrões alimentares em adultos de Viçosa, Minas Gerais: um estudo de base populacional

ABSTRACT Objective The aim of the study was to investigate if there is an association between dietary patterns and bone mineral content among Brazilian adults. Methods This is a cross-sectional, population-based study. Bone health was assessed using dual-energy x-ray absorptiometry. The dietary pattern was obtained using a food frequency questionnaire. An exploratory factor analysis obtained the dietary patterns. Linear regression was used for the multivariate analysis. The research was conducted with adult individuals (20-59 years old) of both sexes residing in the city of Viçosa, MG, Brazil (n=572). Results Two distinct dietary patterns were identified: a "meats and alcoholic drinks" pattern, composed of condiments, alcoholic drinks, dough-based foods, and savory snacks; and a "local traditional" pattern, composed of eggs, beans, trooper's beans, margarine, butter, olive oil, coffee and tea, cereals, and tubers (factor loadings ≥0.20). Having verified the associations considering the confounding factors, we identified that the bone mineral content for males was positively associated with the "local traditional" dietary pattern (β=0.058; 95% CI: 0.003-0.112; p=0.036), and for females an inverse association with the "meats and alcoholic drinks" pattern was found (β=-0.057; 95% CI: -0.110 -0.003; p=0.037). Conclusion We identified a positive association between the local traditional dietary pattern and bone health.

RESUMO Objetivo Investigar se há associação entre padrões alimentares e conteúdo mineral ósseo em adultos brasileiros. Métodos Este é um estudo transversal de base populacional. A saúde óssea de indivíduos adultos (20-59 anos) de ambos os sexos, residentes na cidade de Viçosa, MG, Brasil, (n=572) foi avaliada por meio da absorciometria de raios-X de dupla energia. O padrão alimentar foi obtido através de um questionário de frequência alimentar; a análise fatorial exploratória foi aplicada para obter os padrões alimentares e a regressão linear foi usada para a análise multivariada. Resultados Foram identificados dois padrões alimentares distintos: um padrão "carne e bebidas alcóolicas", composto por condimentos, bebidas alcoólicas, alimentos à base de massa e salgadinhos, e um padrão "local tradicional", composto de ovos, feijões, feijão tropeiro, margarina, manteiga, azeite, café e chá, cereais e tubérculos (cargas fatoriais ≥0,20). Verificadas as associações considerando os fatores de confusão, identificou-se que o conteúdo mineral ósseo para o sexo masculino se associou positivamente ao padrão alimentar "local tradicional" (β=0,058; 95% CI: 0,003-0,112; p=0,036), e para o sexo feminino foi encontrada associação inversa com o padrão "carne e bebidas alcóolicas" (β=-0,057; 95% CI: -0,110 -0,003; p=0,037). Conclusão Uma associação positiva entre o padrão alimentar "local tradicional" e a saúde óssea foi identificada.

Prevalence of dyslipidemias and food consumption: a population-based study. / Prevalência de dislipidemias e consumo alimentar: um estudo de base populacional.

This study aimed to assess the prevalence of dyslipidemia and its association with an adequate intake of carbohydrates, saturated, monounsaturated, trans, and omega-3 fats among adults living in Viçosa, Minas Gerais, Brazil. This is a cross-sectional study with 884 adults aged 20 to 59 years. Sociodemographic, food intake, anthropometric, and biochemical data were collected. Associations between study variables were investigated by the chi-square test. There was a high prevalence of dyslipidemia in the study population (64.25%), with most individuals having abnormal levels of at least one serum lipid component. Inadequate intakes of saturated, trans, and monounsaturated fats and carbohydrates were predominant. It is noteworthy that omega-3 intake levels were adequate in most individuals. Eutrophic adults showed a higher prevalence of excessive intake of saturated and trans fats. It was found that 38.7% of individuals with low levels of High Density Lipoprotein cholesterol (HDL-c) had an excessive intake of saturated fat. Most individuals with high triglyceride levels or high triglyceride/HDL-c ratios had an insufficient intake of monounsaturated fat. Further studies are needed to evaluate other factors that may influence dietary patterns.

O presente artigo objetivou estimar a prevalência de dislipidemias e sua associação e adequação da ingestão de gorduras saturadas, monoinsaturadas, trans, ômega-3 e carboidratos, em adultos de Viçosa-MG. Trata-se de um estudo transversal com 884 adultos com idades entre 20 e 59 anos. Foram coletados dados sociodemográficos, de consumo alimentar, antropométricos e bioquímicos da população. As associações entre as variáveis foram verificadas utilizando-se o teste qui-quadrado. Verificou-se elevada prevalência de dislipidemias na população (64,25%), com pelo menos um dos lipídeos séricos alterados. Houve predomínio de inadequação na ingestão de gorduras saturadas, trans, monoinsaturadas e carboidratos. Ressalta-se que a ingestão de ômega-3 esteve adequado para a maioria dos indivíduos. Adultos eutróficos apresentaram maiores prevalências de ingestão excessiva de gorduras saturadas e trans. Observou-se que 38,7% dos indivíduos com HDL-c reduzido apresentaram ingestão acima do recomendado de gordura saturada. A maioria dos indivíduos com triglicerídeos e razão TG/HDL-c elevada possuíam ingestão insatisfatória de gordura monoinsaturada. Faz-se necessária a avaliação de outros fatores que podem influenciar o padrão alimentar.

Prevalência de dislipidemias e consumo alimentar: um estudo de base populacional / Prevalence of dyslipidemias and food consumption: a population-based study

Resumo O presente artigo objetivou estimar a prevalência de dislipidemias e sua associação e adequação da ingestão de gorduras saturadas, monoinsaturadas, trans, ômega-3 e carboidratos, em adultos de Viçosa-MG. Trata-se de um estudo transversal com 884 adultos com idades entre 20 e 59 anos. Foram coletados dados sociodemográficos, de consumo alimentar, antropométricos e bioquímicos da população. As associações entre as variáveis foram verificadas utilizando-se o teste qui-quadrado. Verificou-se elevada prevalência de dislipidemias na população (64,25%), com pelo menos um dos lipídeos séricos alterados. Houve predomínio de inadequação na ingestão de gorduras saturadas, trans, monoinsaturadas e carboidratos. Ressalta-se que a ingestão de ômega-3 esteve adequado para a maioria dos indivíduos. Adultos eutróficos apresentaram maiores prevalências de ingestão excessiva de gorduras saturadas e trans. Observou-se que 38,7% dos indivíduos com HDL-c reduzido apresentaram ingestão acima do recomendado de gordura saturada. A maioria dos indivíduos com triglicerídeos e razão TG/HDL-c elevada possuíam ingestão insatisfatória de gordura monoinsaturada. Faz-se necessária a avaliação de outros fatores que podem influenciar o padrão alimentar.

Abstract This study aimed to assess the prevalence of dyslipidemia and its association with an adequate intake of carbohydrates, saturated, monounsaturated, trans, and omega-3 fats among adults living in Viçosa, Minas Gerais, Brazil. This is a cross-sectional study with 884 adults aged 20 to 59 years. Sociodemographic, food intake, anthropometric, and biochemical data were collected. Associations between study variables were investigated by the chi-square test. There was a high prevalence of dyslipidemia in the study population (64.25%), with most individuals having abnormal levels of at least one serum lipid component. Inadequate intakes of saturated, trans, and monounsaturated fats and carbohydrates were predominant. It is noteworthy that omega-3 intake levels were adequate in most individuals. Eutrophic adults showed a higher prevalence of excessive intake of saturated and trans fats. It was found that 38.7% of individuals with low levels of High Density Lipoprotein cholesterol (HDL-c) had an excessive intake of saturated fat. Most individuals with high triglyceride levels or high triglyceride/HDL-c ratios had an insufficient intake of monounsaturated fat. Further studies are needed to evaluate other factors that may influence dietary patterns.

Degree of food processing and its relationship with overweight and body adiposity in Brazilian adults / Grau de processamento de alimentos e sua relação com sobrepeso e adiposidade corporal em adultos brasileiros

ABSTRACT Objective To check the relationship of the degree of food processing with overweight and body adiposity in Brazilian adults. Methods Cross-sectional study with 670 adults (334 women and 336 men) aged 20-59 years in Viçosa, Minas Gerais, Brazil, based on population data collected using a questionnaire, 24-hour dietary recall interview, and anthropometric evaluation. Consumed foods were categorized into four groups: unprocessed or minimally processed foods, processed culinary ingredients, processed foods, and ultra-processed foods. Poisson regression models were used to assess the relationship between degree of food processing and overweight and body adiposity. Results The contribution of unprocessed or minimally processed foods to total energy intake was a protective factor for overweight in all quartiles. The contribution of ultra-processed foods to total energy intake was a risk factor for overweight in the highest quartile (prevalence ratio, 1.308; 95% confidence interval, 1.085-1.577). High energy intake from ultra-processed foods was a risk factor for excess adiposity in the highest quartiles. Conclusion Consumption of ultra-processed foods is associated with overweight and excess adiposity, whereas consumption of unprocessed and minimally processed foods is a protective factor for overweight.

RESUMO Objetivo O objetivo deste estudo foi verificar a relação entre o grau de processamento de alimentos e sobrepeso e adiposidade corporal em adultos brasileiros. Métodos Estudo transversal com 670 adultos (334 mulheres e 336 homens) com idades entre 20 e 59 anos, em Viçosa, Minas Gerais, Brasil, com base em dados populacionais coletados por meio de questionário estruturado, entrevista de recordatório alimentar de 24 horas e avaliação antropométrica. Os alimentos consumidos foram categorizados em quatro grupos: alimentos não processados ou minimamente processados, ingredientes culinários processados, alimentos processados e alimentos ultraprocessados. Modelos de regressão de Poisson foram utilizados para avaliar a relação entre o grau de processamento dos alimentos e excesso de peso e de adiposidade corporal. Resultados A contribuição de alimentos não processados ou minimamente processados para a ingestão total de energia foi um fator protetor para o excesso de peso em todos os quartis. Por outro lado, a contribuição dos alimentos ultraprocessados para a ingestão total de energia foi um fator de risco para o excesso de peso no quartil mais alto (razão de prevalência 1,308; intervalo de confiança de 95%, 1,085-1,577). O alto consumo de energia de alimentos ultraprocessados foi um fator de risco para o excesso de adiposidade nos quartis mais altos. Conclusão O consumo de alimentos ultraprocessados está associado ao excesso de peso e excesso de adiposidade, enquanto o consumo de alimentos não processados e minimamente processados é um fator protetor para o excesso de peso.

The mediating role of visceral adiposity in the relationship among schooling, physical inactivity, and unhealthy metabolic phenotype.

OBJECTIVE: To explore the mediating role of visceral adiposity, as assessed by the visceral adiposity index (VAI), in the relationship among schooling, physical inactivity, and unhealthy metabolic phenotype (UMP). METHODS: A cross-sectional population-based study was conducted with 854 adult individuals of both sexes from a Brazilian city. Data were collected through interviews, anthropometric evaluation, and clinical and laboratorial tests. We used multivariate path analysis, which simultaneously analyzes multiple relationships between variables. The analyses were adjusted by sex and age and stratified according to nutritional status. RESULTS: A positive direct effect of visceral adiposity on the UMP was observed for normal weight, standardized estimate (SE) = 0.632; confidence interval (CI 95%) = 0.547, 0.707) and overweight individuals (SE = 0.732; CI 95% = 0.647, 0.808), and negative direct effect of schooling on physical inactivity (normal weight: SE = -0.408; CI 95% = -0.550, -0.265) and overweight (SE = -0.304; CI 95% = -0.479, -0.129). Among normal-weight individuals, there was a positive direct effect (SE = 0.193; CI 95% = 0.059, 0.328) of physical inactivity on VAI. In relation to indirect effects, there was a mediating role of visceral adiposity in the association of schooling level and physical inactivity with the UMP only among normal-weight individuals. CONCLUSIONS: Visceral adiposity has a direct effect on the UMP regardless of nutritional status, and there is a mediating effect of VAI on the relationship among schooling, physical inactivity, and UMP in normal-weight individuals.

O nível de condicionamento físico interfere nas respostas psicofisiológicas?

Resumo Objetivou-se avaliar se o nível de condicionamento físico interfere na resposta psicofisiológica durante a corrida. Quinze atletas (25, 3 ± 2, 4 anos) corredores de fundo (G1) e 15 indivíduos ativos (23, 1 ± 4, 3 anos) não atletas (G2) fizeram uma sessão de corrida de 80 min com intensidade controlada entre 75 e 85% da frequência cardíaca de reserva. A cada 10 min os avaliados responderam a escalas de percepção subjetiva de esforço (PSE), sensação térmica (ST), conforto térmico (CT), sensação de sede (SS), náusea (SN) e plenitude gástrica (PG). Houve diferença significativa (p = 0,020) entre G1 vs. G2 na PSE a partir dos 40 min e no CT após 50 min (p < 0,001). Conclui-se que o nível de condicionamento físico interfere somente na PSE e no CT durante o exercício de corrida.

Abstract The aim was to evaluate whether the physical conditioning level interferes in the psychophysiological responses during the running. Fifteen long-distance runner athletes (25.3 ± 2.4 years) (G1) and fifteen non-athlete active subjects (23.1 ± 4.3 years) (G2) performed a 80 min running session with intensity between 75 and 85% of heart rate reserve. Every 10 min the participants reported the rates of perceived exertion (RPE), thermal sensation (TS), thermal comfort (TC), sensation of thirst (ST), nausea (SN) and fullness (SF). There was a significant difference between G1 vs G2 in the RPE (p = 0.020) since 40 min and in the TC (p< 0.001) since 50 min We conclude that the physical conditioning level affects the RPE and TC during the long-distance running.

Resumen El objetivo del estudio fue evaluar si el nivel de preparación física influye en la respuesta psicofisiológica durante la carrera. Quince atletas (25, 3 ± 2, 4 años), corredores de larga distancia (G1) y 15 individuos activos, pero no atletas (25, 3 ± 2, 4 años) (G2) corrieron durante 80 minutos con una intensidad controlada entre el 75 y el 85% de su frecuencia cardíaca de reserva. Durante intervalos de 10 minutos, los evaluados respondieron a escalas de percepción subjetiva del esfuerzo (PSE), sensación térmica (ST), comodidad térmica (CT), sensación de sed (SS), sensación de náuseas (SN) y plenitud gástrica (PG). Se obtuvieron diferencias considerables entre G1 y G2 en la PSE (p = 0,020) a partir de los 40 minutos y la CT solamente después de 50 minutos (p < 0,001). Se concluye que el nivel de preparación física influye solamente sobre la PSE y la CT durante la práctica de la carrera.

Visceral adiposity index is a better predictor of unhealthy metabolic phenotype than traditional adiposity measures: results from a population-based study.

OBJECTIVE: The present study aimed to investigate whether the visceral adiposity index (VAI) is an effective predictor to identify unhealthy metabolic phenotype by comparing normal-weight and overweight individuals. DESIGN: A population-based cross-sectional study. Data were collected by interviews, anthropometric evaluation, dietetic, clinical and laboratory tests. The area under the receiver-operating characteristic curve (AUC) and prevalence ratio (PR), obtained from Poisson regression, were used to compare the predictive capacity of the obesity indicators evaluated (VAI, BMI, waist and neck circumference, waist-to-height and waist-to-hip ratios) and their association with the unhealthy metabolic phenotype. All analyses were stratified by sex and by nutritional status. SETTING: Viçosa, Minas Gerais, Brazil.ParticipantsA total of 854 Brazilian adults (20-59 years old) of both sexes. RESULTS: VAI was the best predictor for unhealthy metabolic phenotype among men (AUC = 0·865) and women (AUC = 0·843) at normal weight. VAI also had the best predictive capacity among overweight women (AUC = 0·903). Among overweight men, its accuracy (AUC = 0·830) was higher than that of waist-to-hip ratio. In the adjusted regression models, VAI was the indicator most strongly associated with the unhealthy metabolic phenotype, especially among those with normal weight (PR = 6·74; 95 % CI 3·15, 14·42 for men; PR = 7·14; 95 % CI 3·79, 13·44 for women). CONCLUSIONS: VAI has better predictive capacity in detecting unhealthy metabolic phenotype than conventional anthropometric indicators, regardless of nutritional status and sex.

Excessive abdominal adiposity and body fat are associated with lower serum vitamin D levels: A population-based study / Excesso de adiposidade abdominal e de gordura corporal se associa à menor concentração sérica de vitamina D: um estudo de base populacional

ABSTRACT Objective To estimate the prevalence of 25-hydroxyvitamin D deficiency and to analyze factors associated with lower serum vitamin levels in Brazilian adults. Methods A cross-sectional, population-based study consisted of 626 adult individuals of both sexes living in the urban area of Viçosa, Minas Gerais. The dependent variable used was the serum level of 25-hydroxyvitamin D and the independent variables were sociodemographic, anthropometric and body composition variables. The associations among the variables were verified using simple and multiple linear regression models, considering alpha lower than 0.05 for the input in the final model. Results The prevalence of 25-hydroxyvitamin D deficiency was 14.4% and the prevalence was 42.0%. Excess abdominal fat was higher in subjects with 25-hydroxyvitamin D sufficiency. The serum level of 25-hydroxyvitamin D was 30.34±9.85ng/ml. Body adiposity was higher in men with vitamin insufficiency. Negative associations were observed between serum 25-hydroxyvitamin D levels and age, educational level, body adiposity (p=0.028) and abdominal adiposity (p=0.023). Conclusion Our results showed that excess body and abdominal adiposity are strong predictors of alterations in the serum vitamin D levels, thus public policies for prevention and treatment in this population are essential.

RESUMO Objetivo Estimar a prevalência de deficiência de 25 hidroxivitamina D e analisar fatores associados à menor concentração sérica da vitamina em adultos brasileiros. Métodos Estudo transversal, de base populacional, realizado com 626 indivíduos adultos, de ambos os sexos, residentes na área urbana do município de Viçosa, Minas Gerais. A variável dependente utilizada foi a concentração sérica de 25 hidroxivitamina D e as independentes foram variáveis sociodemográficas, antropométricas e de composição corporal. As associações entre as variáveis foram verificadas utilizando-se modelos de regressão linear simples e múltipla, considerando alfa menor que 0,05 para a entrada no modelo final. Resultados A prevalência de deficiência de 25 hidroxivitamina D foi de 14,4% e a insuficiência de 42,0%. O excesso de gordura abdominal foi maior em indivíduos com suficiência de 25 hidroxivitamina D. A concentração sérica de 25 hidroxivitamina D foi de 30,34±9,85 ng/ml. A adiposidade corporal foi maior em homens com insuficiência. Foram verificadas associações negativas entre a concentração sérica de 25 hidroxivitamina D e a idade, a escolaridade, a adiposidade corporal (p=0,028) e a adiposidade abdominal (p=0,023). Conclusão Nossos resultados mostraram que o excesso de adiposidade corporal e abdominal são fortes preditores de alterações na concentração sérica de vitamina D, por isso, é importante que condutas públicas de prevenção e tratamento sejam estabelecidas nesta população.

Visceral adiposity index associated with behavioral and inflammatory parameters in adults: a population based study.

INTRODUCTION: the visceral adiposity index (VAI) is an indicator of fat distribution and function which is considered a predictor of cardiometabolic risk. OBJECTIVE: analyze the factors associated with VAI in Brazilian adults. METHODS: a cross-sectional population-based study was conducted with 854 adults, in Viçosa, MG, Brazil. A questionnaire was applied and anthropometric measurements, body composition and biochemical data were collected. Ordinal logistic regression was used to evaluate the factors associated with VAI. RESULTS: the increase in percentage of fat, uric acid concentration and ultra-sensitive C reactive protein in the blood was positively associated with VAI in males. The level of physical activity in leisure was negatively associated. Among women, the increase in age, neck circumference, sitting time of more than 300 minutes, increased serum uric acid concentration and ultra-sensitive C reactive protein were associated with VAI. CONCLUSION: except for age, all other factors associated with VAI are modifiable, suggesting that adopting early intervention measures that promote changes in habits and alter the risk of increased visceral adiposity and consequently the appearance of comorbidities should be encouraged.

Visceral adiposity index associated with behavioral and inflammatory parameters in adults: a population based study / Índice de adiposidad visceral asociado con parámetros inflamatorios y del comportamiento: estudio transversal de población

Introduction: the visceral adiposity index (VAI) is an indicator of fat distribution and function which is considered a predictor of cardiometabolic risk. Objective: analyze the factors associated with VAI in Brazilian adults. Methods: a cross-sectional population-based study was conducted with 854 adults, in Viçosa, MG, Brazil. A questionnaire was applied and anthropometric measurements, body composition and biochemical data were collected. Ordinal logistic regression was used to evaluate the factors associated with VAI. Results: the increase in percentage of fat, uric acid concentration and ultra-sensitive C reactive protein in the blood was positively associated with VAI in males. The level of physical activity in leisure was negatively associated. Among women, the increase in age, neck circumference, sitting time of more than 300 minutes, increased serum uric acid concentration and ultra-sensitive C reactive protein were associated with VAI. Conclusion: except for age, all other factors associated with VAI are modifiable, suggesting that adopting early intervention measures that promote changes in habits and alter the risk of increased visceral adiposity and consequently the appearance of comorbidities should be encouraged

Introducción: el índice de adiposidad visceral (VAI) es un indicador de distribución y función de la grasa que se considera un predictor del riesgo cardiometabólico. Objetivo: analizar los factores asociados con el VAI en adultos brasileños. Métodos: se realizó un estudio transversal de población con 854 adultos, en Viçosa, MG, Brasil. Se aplicó un cuestionario y se analizaron las medidas antropométricas, la composición corporal y los datos bioquímicos. La regresión logística ordinal se utilizó para evaluar los factores asociados con VAI. Resultados: el aumento en el porcentaje de grasa, la concentración de ácido úrico y la proteína C reactiva ultrasensible en la sangre se asoció positivamente con VAI en varones. El nivel de actividad física en el ocio se asoció negativamente. Entre las mujeres, el aumento de la edad, la circunferencia del cuello, el tiempo en sedestación de más de 300 minutos, el aumento de la concentración sérica de ácido úrico y la proteína C reactiva ultrasensible se asociaron con VAI. Conclusión: con excepción de la edad, todos los otros factores asociados con el VAI son modificables, lo que sugiere que debe fomentarse la adopción de medidas de intervención temprana que promuevan cambios en los hábitos y alteren el riesgo de aumento de la adiposidad visceral y, consecuentemente, la aparición de comorbilidades

Association of eating patterns and abdominal adiposity in Brazilian / Associação de padrões alimentares e adiposidade abdominal em adultos brasileiros

ABSTRACT Objective To examine the relationship between dietary patterns and abdominal adiposity among adults living in the urban area of Viçosa, Minas Gerais, Brazil. Methods A population-based, cross-sectional study of 959 adults of both sexes. Information on sociodemographic characteristics and dietary intake was collected through questionnaires. Abdominal adiposity was evaluated using waist circumference and the anthropometric indices waist-to-hip ratio and waist-to-height ratio. Food patterns were identified by factor analysis. Poisson regression was used for multivariate analysis. Results Abdominal adiposity was identified by waist circumference in 59.06% (95%CI=52.77-65.08) of the sample, by waist-to-hip ratio in 54.65% (95%CI=47.92-61.21), and by waist-to-height ratio in 9% (95%CI=54.61-69.03). Two dietary patterns, named as traditional Brazilian and bar, were identified in the sample, but only the latter was statistically associated with abdominal adiposity determined by the three parameters. Conclusion The study identified two eating patterns in the population, a healthy and an unhealthy pattern, the latter being associated with greater odds of abdominal adiposity. Thus, it is important to take measures to reverse this trend.

RESUMO Objetivo Explorar a relação entre padrões alimentares e a adiposidade abdominal entre adultos residentes na área urbana do município de Viçosa, Minas Gerais. Métodos Estudo transversal, de base populacional, realizado com 959 indivíduos adultos e de ambos os sexos. Foram coletadas informações sobre as características sociodemográficas e de consumo alimentar por meio de questionários. Para avaliação da adiposidade abdominal, avaliou-se o perímetro da cintura e os índices antropométricos relação cintura/quadril e relação cintura/estatura. Os padrões alimentares foram identificados por análise fatorial. Para análise multivariada, foi utilizada regressão de Poisson. Resultados A adiposidade abdominal identificada pela perímetro da cintura foi de 59,06% (IC95%=52,77-65,08), pela relação cintura/quadril foi de 54,65% (IC95%=47,92-61,21) e pela relação cintura/estatura de 62,09% (IC95%=54,61-69,03). Foram identificados dois padrões alimentares, nomeados de padrão "tradicional" e "bar", sendo que somente o último padrão foi estatisticamente associado à adiposidade abdominal determinada pelos três parâmetros. Conclusão A população do estudo apresentou dois padrões alimentares, um considerado saudável e outro não saudável, o qual foi associado à maior chance de adiposidade abdominal. Sendo assim, medidas que revertam tais situações são importantes de serem adotadas.

Chronic joint symptoms in adults: A population-based study.

OBJECTIVE: To analyze factors associated with chronic joint symptoms (CJS) in adults. METHOD: A population-based, cross-sectional study was performed with a sample of 1,217 adults aged between 20 and 59 years, in the city of Viçosa, in 2014. The sampling process was performed by conglomerates and sample was selected using a two-stage cluster-sampling scheme. First, 30 of the 99 census tracts of Viçosa were randomly selected using a random sampling scheme, without replacement. Household questionnaires were applied to obtain CJS data, sociodemographic conditions, behavioral factors and health status. Multivariable analysis was conducted using Poisson regression, adjusted for the sampling design effect, using the svy commands in Stata software. RESULTS: Prevalence of CJS totaled 31.27%, significantly higher in women (18.45). Age ranges 40-49 (PR 1.50; 95CI 1.16-1.92) and 50-59 years (PR 1.55; 95CI 1.07-2.25); overweight (PR 1.60; 95CI 1.28-2.00); obesity (PR 1.60; 95CI 1.11-2.29); and those who self-reported performing heavy work (PR 1.27; 95CI 1.09-1.48) showed higher prevalences of CJS. CONCLUSION: Women and individuals who were older, overweight and performing heavy work had a higher risk of CJS in this adult population residing in Viçosa, MG, Brazil.

Chronic joint symptoms in adults: A population-based study / Sintomas articulares crônicos em adultos: um estudo de base populacional

Summary Objective: To analyze factors associated with chronic joint symptoms (CJS) in adults. Method: A population-based, cross-sectional study was performed with a sample of 1,217 adults aged between 20 and 59 years, in the city of Viçosa, in 2014. The sampling process was performed by conglomerates and sample was selected using a two-stage cluster-sampling scheme. First, 30 of the 99 census tracts of Viçosa were randomly selected using a random sampling scheme, without replacement. Household questionnaires were applied to obtain CJS data, sociodemographic conditions, behavioral factors and health status. Multivariable analysis was conducted using Poisson regression, adjusted for the sampling design effect, using the svy commands in Stata software. Results: Prevalence of CJS totaled 31.27%, significantly higher in women (18.45). Age ranges 40-49 (PR 1.50; 95CI 1.16-1.92) and 50-59 years (PR 1.55; 95CI 1.07-2.25); overweight (PR 1.60; 95CI 1.28-2.00); obesity (PR 1.60; 95CI 1.11-2.29); and those who self-reported performing heavy work (PR 1.27; 95CI 1.09-1.48) showed higher prevalences of CJS. Conclusion: Women and individuals who were older, overweight and performing heavy work had a higher risk of CJS in this adult population residing in Viçosa, MG, Brazil.

Resumo Objetivo: Analisar os fatores associados aos sintomas articulares crônicos (SAC) em adultos. Método: Trata-se de um estudo transversal, de base populacional, com 1.217 adultos, na faixa etária de 20 a 59 anos, na cidade de Viçosa, MG, 2014. A amostragem foi realizada por conglomerados em duplo estágio, sendo as unidades de primeiro estágio os setores censitários, e, em seguida, os domicílios. Foram sorteados 30 setores dentre os 99 de Viçosa, por meio de amostragem casual simples, sem reposição. A coleta de dados foi composta por aplicação de questionário contendo questões relativas a variáveis de SAC, sociodemográficas, comportamentais e de saúde. Para verificar as associações, apresentaram-se proporções, razões de prevalência e seus respectivos intervalos de confiança de 95%. A análise múltipla foi realizada por meio da regressão de Poisson, utilizando o conjunto de comandos svy do software Stata, o qual considera o efeito da expansão da amostra na análise dos dados. Resultados: A prevalência estimada de SAC foi de 31,27%, maior nas mulheres (18,45%). Estiveram associadas ao SAC as mulheres (RP 1,49; IC95% 1,23-1,81); as idades de 40 e 49 (RP 1,50; IC95% 1,16-1,92) e 50 e 59 anos (RP 1,55; IC95% 1,07-2,25); o sobrepeso (RP 1,60; IC95% 1,28-2,00); a obesidade (RP 1,60; IC95% 1,11-2,29); e aqueles que autorreferiram realização de trabalho pesado (RP 1,27; IC95% 1,09-1,48). Conclusão: O sexo feminino, a faixa etária de 40 a 59 anos, o sobrepeso, a obesidade e a realização de trabalho pesado foram fatores de risco para SAC em adultos de Viçosa, MG.