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Coating thermal noise is a fundamental limit for precision experiments based on optical and quantum transducers. In this review, after a brief overview of the techniques for coating thermal noise measurements, we present the latest worldwide research activity on low-noise coatings, with a focus on the results obtained at the Laboratoire des Matériaux Avancés. We report new updated values for the Ta2O5, Ta2O5-TiO2, and SiO2 coatings of the Advanced LIGO, Advanced Virgo, and KAGRA detectors, and new results from sputtered Nb2O5, TiO2-Nb2O5, Ta2O5-ZrO2, MgF2, AlF3, and silicon nitride coatings. Amorphous silicon, crystalline coatings, high-temperature deposition, multi-material coatings, and composite layers are also briefly discussed, together with the latest developments in structural analyses and models.
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For the first time, direct detection of gravitational waves occurred in the Laser Interferometer Gravitational-wave Observatory (LIGO) interferometers. These advanced detectors require large fused silica mirrors with optical and mechanical properties and have never been reached until now. This paper details the main achievements of these ion beam sputtering coatings.
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Oral processing during bread consumption is a key process related to the dynamics of texture perceptions, sensory stimuli release and starch digestion. The aim of this study was to determine the respective contribution of bread properties (composition and structure of crumb and crust) and of the oral physiology of subjects to the breakdown pathways in the mouth. The properties of the in vivo bread bolus obtained from eight healthy subjects were studied at three key points in time during their oral processing. The progressive lubrication and breakdown of bread were observed, as well as the beginning of the enzymatic degradation of starch. The study showed that "time" was the factor responsible for the greatest variability in bolus properties. Breakdown pathways were established for crumbs with and without crust. The presence of crust modified the oral processing, increasing, for instance, the heterogeneity of particle size at the middle of the oral processing sequence. Moreover, the hydration capacity of crust contributed to high starch degradation at swallowing time, in comparison with crumb alone. The main subject characteristics impacting bolus properties were the in-mouth duration, the individual masticatory index and the mouth volume, while the main bread properties explaining the bolus properties were the initial composition and the water-absorbing capacity. We concluded that both crumb and crust structures had an impact on the oral processing, affecting the capacity of hydration, the rheology and the breakdown degree of the bolus.
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Pão/análise , Digestão , Boca/metabolismo , Triticum/química , Adulto , Feminino , Humanos , Masculino , Tamanho da Partícula , Reologia , Amido/análise , Amido/metabolismo , Paladar , Triticum/metabolismo , Água/análise , Água/metabolismo , Adulto JovemRESUMO
The new generation of advanced interferometer needs fused silica mirrors having better optical and mechanical properties. This Letter describes the way to reduce the ion beam sputtering coating absorption at 1064 nm and to improve the layer thickness uniformity in order to coat two large mirrors (diameter 35 cm) at the same time.
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Collinear laser spectroscopy was performed on Ga (Z=31) isotopes at ISOLDE, CERN. A gas-filled linear Paul trap (ISCOOL) was used to extend measurements towards very neutron-rich isotopes (N=36-50). A ground state (g.s.) spin I=1/2 is measured for 73Ga, being near degenerate with a 3/2{-} isomer (75 eVâ²E{ex}â²1 keV). The 79Ga g.s., with I=3/2, is dominated by protons in the πf{5/2} orbital and in 81Ga the 5/2{-} level becomes the g.s. The data are compared to shell-model calculations in the f{5/2}pg{9/2} model space, calling for further theoretical developments and new experiments.
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We report the first confirmation of the predicted inversion between the pi2p3/2 and pi1f5/2 nuclear states in the nu(g)9/2 midshell. This was achieved at the ISOLDE facility, by using a combination of in-source laser spectroscopy and collinear laser spectroscopy on the ground states of 71,73,75Cu, which measured the nuclear spin and magnetic moments. The obtained values are mu(71Cu)=+2.2747(8)mu(N), mu(73Cu)=+1.7426(8)mu(N), and mu(75Cu)=+1.0062(13)mu(N) corresponding to spins I=3/2 for 71,73Cu and I=5/2 for 75Cu. The results are in fair agreement with large-scale shell-model calculations.
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A new method of optical pumping in an ion beam cooler buncher has been developed to selectively enhance ionic metastable state populations. The technique permits the study of elements previously inaccessible to laser spectroscopy and has been applied here to the study of Nb. Model independent mean-square charge radii and nuclear moments have been studied for ;{90,90 m,91,91 m,92,93,99,101,103}Nb to cover the region of the N=50 shell closure and N approximately 60 sudden onset of deformation. The increase in mean-square charge radius is observed to be less than that for Y, with a substantial degree of beta softness observed before and after N=60.
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We have tested a new kind of Fabry-Perot long-baseline optical resonator proposed to reduce the thermal noise sensitivity of gravitational wave interferometric detectors--the "mesa beam" cavity--whose flat top beam shape is achieved by means of an aspherical end mirror. We present the fundamental mode intensity pattern for this cavity and its distortion due to surface imperfections and tilt misalignments, and contrast the higher order mode patterns to the Gauss-Laguerre modes of a spherical mirror cavity. We discuss the effects of mirror tilts on cavity alignment and locking and present measurements of the mesa beam tilt sensitivity.
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In marine sedimentary habitats, chemoreception is thought to coordinate feeding in many deposit-feeding invertebrates such as polychaetes, snails, and clams. Relatively little is known, however, about the chemosensory structures and mechanism of signal transduction in deposit feeders. Using electron microscopy, confocal laser scanning microscopy (CLSM), and immunohistochemistry, we investigated the structure and function of putative chemosensory cells on the feeding appendages of a deposit-feeding polychaete species, Dipolydora quadrilobata. Tufts of putative sensory cilia were distributed over the prostomium and feeding palps and typically occurred next to pores. Examination of these regions with transmission electron microscopy revealed multiciliated cells with adjacent glandular cells beneath the pores. The sensory cells of prostomium and palps were similar, displaying an abundance of apical mitochondria and relatively short ciliary rootlets. Staining with antiserum against acetylated alpha-tubulin was examined by CLSM, and revealed axonal processes from putative sensory tufts on the palp surface to palp nerves, as well as many free nerve endings. Activity-dependent cell labeling experiments were used to test the sensitivity of putative sensory cells on the palps to an amino acid mixture that elicited feeding in previous behavioral experiments. In static exposures, the number of lateral and abfrontal cells labeled in response to the amino acid mixture was significantly greater than in the controls. Ultrastructural, positional, and now physiological evidence strongly suggests that spionid feeding palps are equipped with sensory cells, at least some of which function as chemoreceptors.
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Células Quimiorreceptoras/ultraestrutura , Poliquetos/anatomia & histologia , Transdução de Sinais/fisiologia , Aminoácidos/metabolismo , Animais , Cílios/ultraestrutura , Comportamento Alimentar/fisiologia , Guanidina , Imuno-Histoquímica , Maine , Microscopia Confocal , Microscopia Eletrônica , Neurônios/ultraestrutura , Poliquetos/fisiologia , Receptores de Superfície Celular , Coloração e Rotulagem , Tubulina (Proteína)RESUMO
The first on-line laser spectroscopy of cooled fission fragments is reported. The r ions, produced in uranium fission, were extracted and separated using an ion guide isotope separator. The ions were cooled and bunched for collinear laser spectroscopy by a gas-filled linear Paul trap. New results for nuclear mean-square charge radii, dipole, and quadrupole moments are reported across the N=60 shape change. The mean-square charge radii are found to be almost identical to those of the Sr isotones and previously offered modeling of the radial changes is critically reviewed.
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A new method has been developed for increasing the sensitivity of collinear laser spectroscopy. The method utilizes an ion-trapping technique in which a continuous low-energy ion beam is cooled and accumulated in a linear Paul trap and subsequently released as a short (10-20 micros) bunch. In collinear laser measurements the signal-to-noise ratio has been improved by a factor of 2 x 10(4), allowing spectroscopic measurements to be made with ion-beam fluxes of approximately 50 ions s(-1). The bunching method has been demonstrated in an on-line isotope shift and hyperfine structure measurement on radioactive (175)Hf.
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The formation of cryptophane-A (C1) and the deuterated cryptophanes C2-C6 from their respective precursors P1-P6 in a mass spectrometer ion-source was evidenced by liquid secondary ion mass spectrometry (LSIMS). Mass-analyzed ion kinetic energy experiments performed on the precursor molecular ions suggested that cryptophane formation occurred mainly in the liquid-matrix before desorption rather than in the gas phase. In addition, we observed that the presence of cations, such as lithium or sodium ions, inhibited the formation of the cryptophane molecular ions. In the light of these results we used the LSIMS technique to investigate the formation of the new cryptophanes C7-C13. All the data collected support the idea that a direct comparison can be made between these experimental findings and chemistry in solution.
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Samples of corn available as wildlife feed from retailers throughout Georgia (USA) were collected during April 1997 and analyzed for aflatoxin to determine if levels harmful to wild turkeys (Meleagris gallopavo) were present. Three of 31 (10%) samples collected from a 40-country area were positive. An enzyme-linked immunosorbent assay qualitatively determined that two samples contained from 0 to 20 ppb aflatoxin. A chromatography analysis of a third sample measured 380 ppb total aflatoxin. A small percentage of our sample of wildlife feed collected during one season contained levels of aflatoxin that may cause harm to turkeys, especially poults. However, because aflatoxin levels ranging from 100 to 400 ppb may cause liver dysfunction and immunosuppression in turkey poults and other wildlife, grains known to be contaminated with aflatoxin at levels unacceptable for domestic animal feeds (> or =100 ppb) should not be sold as wildlife feed. Further analyses of grains sold as wildlife feed should be conducted to address this potential problem.
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Aflatoxinas/biossíntese , Ração Animal/microbiologia , Doenças das Aves/etiologia , Micotoxicose/veterinária , Perus , Zea mays/microbiologia , Aflatoxinas/intoxicação , Animais , Animais Selvagens , Doenças das Aves/prevenção & controle , Contaminação de Alimentos , Georgia , Micotoxicose/etiologia , Micotoxicose/prevenção & controleRESUMO
Electrical dental anesthesia has recently been suggested as an alternative to local anesthetics for the control of pain related to certain dental acts. This article updates the evidence which supports the efficiency, indications and contra-indications of such a procedure. Although this technique has certain advantages, its use is limited by: 1) how cooperative the patient may be; 2) the time required to explain the procedure to the patient and that which is required to produce the needed clinical effect; and, 3) how efficient it may be relative to the patient in question and the dental treatment rendered.
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Anestesia Dentária/métodos , Eletronarcose/instrumentação , Estimulação Elétrica Nervosa Transcutânea , Anestesia Dentária/instrumentação , HumanosRESUMO
The radiopacity of glass ionomer dental materials is quite variable. The use of a poorly radiopaque material as a base under other restorative materials can mislead the dentist to a diagnosis of recurrent decay. This study investigates the radiopacity of these materials and proposes a minimal radiopacity under which a material should not be used as a base or liner. All base, liner, and core formulations of glass ionomer under investigation were more radiopaque than dentin. All restorative and luting formulations of glass ionomer under investigation were less radiopaque than dentin and therefore should be avoided as bases or liners.
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Cimentos de Ionômeros de Vidro , Radiografia Dentária , Análise de Variância , Meios de Contraste , Amálgama Dentário , Esmalte Dentário/diagnóstico por imagem , Polpa Dentária/diagnóstico por imagem , Dentina/diagnóstico por imagem , Humanos , Variações Dependentes do Observador , Resinas SintéticasRESUMO
This article relates to the technique of computerized tomography. New indications for this technique are described and especially those used in implantology. Several axial and coronal sections are presented.
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Radiografia Dentária/métodos , Tomografia Computadorizada por Raios X/métodos , Absorciometria de Fóton , Implantação Dentária Endóssea , Humanos , Cuidados Pré-OperatóriosRESUMO
Reverse-phase thin-layer chromatography of 18 common mycotoxins was carried out on Merck C18 and Whatman C18 and diphenyl bonded phases. The mobile phases included neutral and acidified binary mixtures of water and methanol, acetonitrile or tetrahydrofuran. Mycotoxins studied included aflatoxins B1, B2, G1, G2, sterigmatocystin, ochratoxin A, citrinin, penicillic acid, patulin, zearalenone, and the trichothecenes diacetoxyscirpenol, HT-2 toxin, nivalenol, neosolaniol, fusarenone-X, T-2 toxin, deoxynivalenol and 3-acetyl-deoxynivalenol. Both C18-bonded phases performed well, and could serve as a convenient confirmation for mycotoxins appearing in normal-phase (silica) thin-layer chromatographic screening procedures.
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Micotoxinas/análise , Cromatografia em Camada FinaRESUMO
Two cases of mandibular infected buccal cyst are presented. A thorough review of the literature reveals that this is a fairly new entity with the first cases reported by Stoneman and Worth in 1983.
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Cistos Maxilomandibulares/patologia , Doenças Mandibulares/patologia , Criança , Diagnóstico Diferencial , Humanos , Inflamação , Masculino , Dente/patologiaRESUMO
Not all patients with cervicopharyngeal pain related to the stylohyoid apparatus can be diagnosed as having Eagle's syndrome. An attempt is therefore made to classify these patients according to etiology. First, a diagnosis of Eagle's syndrome is applied to symptomatic patients in whom elongated, ossified styloid processes develop within a period of time posttraumatically. Second, a diagnosis of stylohyoid syndrome is applied to patients in whom elongated styloid processes and/or stylohyoid chain ossification develop early in life as an anatomic anomaly, and in whom symptoms later develop. Last, a diagnosis of pseudostylohyoid syndrome is applied to patients in whom, because of aging, a tendinosis at the junction of the stylohyoid ligament and the lesser horn of the hyoid bone develops. It is hoped that such a simplified classification may lead to a global understanding of the causes of such symptomatology, a more practical approach to treatment, and less confusion among the professions in regard to terminology.