Does maternity during sports career jeopardize future athletic success in elite marathon runners?

The impact of maternity (Mat) on subsequent athletic performance is not well known. This study aims to investigate the impact of maternity among elite marathoners on their overall performance progression. For each runner listed in the top 150 female marathoners, who had experienced a mid-career maternity, performance development was reconstituted throughout the career. Maternity data and career break time span (Ttotal) were collected from publicly available informations. Performances were modelled according to the known age-performance relationship and the impact of maternity was added into the model. Linear mixed effect model was used to study the influence of maternity on the overall career. Among this sample, 37 runners had at least 1 child during her career. Among them, 14 had 2 children. Eleven runners (29.72%) made their personal best performance before Mat, which occurred at an average age of 28.40 ± 4.00 years. Twenty-six runners (70.28%) establish their best performances after Mat, at an average age of 32.20 ± 4.28. The age-performance relationship model explains 92% of the performance variability during the career's progression. When age is considered, maternity does not have significant impact on performance development. World's most competitive marathoners can still perform at their best level after pregnancy. The ability to return and surpass previous performance level is influenced by the age at which pregnancy occurs, relative to the age of peak performance during career development.HighlightsMid-career maternity does not have a significant impact on overall progression in high level runners, who return to official races.The ability to return and surpass previous performance level is influenced by the age at which pregnancy occurs, relative to the age of peak performance.Age is the variable that explains most of performance progression, independently of mid-career maternity occurrence(s).

Digital phenotyping in young breast cancer patients treated with neoadjuvant chemotherapy (the NeoFit Trial): protocol for a national, multicenter single-arm trial.

BACKGROUND: Breast cancer (BC) has particular characteristics in young women, with diagnosis at more advanced stages, a poorer prognosis and highly aggressive tumors. In NeoFit, we will use an activity tracker to identify and describe various digital profiles (heart rate, physical activity, and sleep patterns) in women below the age of 45 years on neoadjuvant chemotherapy for BC. METHODS: NeoFit is a prospective, national, multicenter, single-arm open-label study. It will include 300 women below the age of 45 years treated with neoadjuvant chemotherapy for BC. Participants will be asked to wear a Withing Steel HR activity tracker round the clock for 12 months. The principal assessments will be performed at baseline, at the end of neoadjuvant chemotherapy and at 12 months. We will evaluate clinical parameters, such as toxicity and the efficacy of chemotherapy, together with quality of life, fatigue, and parameters relating to lifestyle and physical activity. The women will complete REDCap form questionnaires via a secure internet link. DISCUSSION: In this study, the use of an activity tracker will enable us to visualize changes in the lifestyle of young women on neoadjuvant chemotherapy for BC, over the course of a one-year period. This exploratory study will provide crucial insight into the digital phenotypes of young BC patients on neoadjuvant chemotherapy and the relationship between these phenotypes and the toxicity and efficacy of treatment. This trial will pave the way for interventional studies involving sleep and physical activity interventions. TRIAL REGISTRATION: Clinicaltrials.gov identifier: NCT05011721 . Registration date: 18/08/2021.

Involvement in Multiple Race Events Among International Para and Non-disabled Swimmers.

International elite Para swimmers form a large portion of the overall multi-medalist winning population. For the highest performing Para swimmers, world class performances were achieved across different strokes. The aim of this study was to quantify the level of involvement across different events and to examine this in relation to the level of performance. The performances in swimming speed of the top 100 females and males for both Para- and non-disabled swimmers were collected in 11 race events between 2009 and 2019 (4,400 performances for 307 Para females and 365 Para males, 605 non-disabled females, and 715 non-disabled males). We tallied the number of events in which each swimmer was involved. Swimmers were grouped according to the total number of race events in which they participated. Then the association between involvement and level of performance was investigated. Para swimmers with impairment from classes seven to 14 were involved in a range of race events across different strokes. The most common combination for both Para and non-disabled athletes was over similarly distanced races of the same stroke (50 and 100 m freestyle). The more race events in which Para swimmers involved, the higher the level of performance that was achieved. This trend can partially be explained by the less concentrated competition pool for Para swimmers compared to able-bodied swimmers. Para swimmers with minimal and no physical impairment perform in multiple race events more often than able-bodied swimmers. Fewer Para swimmers at the international level and a less concentrated competition pool could explain these differences.