Anaplastic large cell lymphoma mimicking noduloulcerative tertiary syphilis.

Anaplastic large cell lymphoma (ALCL) is a recently described malignancy that can show heterogeneity in its clinical presentation. We report on a patient whose clinical presentation, medical history, and serologic test results were suggestive of tertiary syphilis. Histologic evaluation, however, revealed a large cell lymphoma with Ki-1 positive findings on immunostaining. We review the differential diagnosis of ALCL and add to that a pattern of ALCL clinically mimicking noduloulcerative tertiary syphilis.