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1.
J Equine Vet Sci ; 78: 134-137, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31203977

RESUMO

A 20-year-old Paint gelding was evaluated for fever of unknown origin. History and clinical signs were consistent with potential tick-borne disease. Samples were collected and submitted for tick-borne disease panel, herpes virus, complete blood count, and serum biochemistry. Based on physical examination findings and vaccination history, the gelding was treated for suspected tick-borne disease with oxytetracycline (8 mg/kg intravenously BID) for 5 days, followed by doxycycline (10 mg/kg PO BID) for an additional 5 days. Although titers to Borrelia burgdorferi, Anaplasma phagocytophilum, and Neorickettsia risticii on Days 4 and 8 were negative, the Rickettsia rickettsii titer went from 1:1,600 on Day 4 to 1:800 on Day 8, 1:100 on Day 21, and was seronegative by Day 38. Although complete blood polymerase chain reaction for Rickettsia rickettsii was negative, the clinical and serologic features of this case are extremely consistent with clinical cases of Rocky Mountain Spotted Fever (RMSF) described in both dogs and humans. Therefore, we submit this case report to document suspected clinical infection of an adult horse in the southeastern United States with Rickettsia rickettsii, the causative agent of RMSF. Other relevant differentials (i.e., Rickettsia parkeri, Theileria equi, and Babesia caballi) are also discussed.


Assuntos
Doenças dos Cavalos/diagnóstico , Rickettsia , Febre Maculosa das Montanhas Rochosas/veterinária , Animais , Doxiciclina/uso terapêutico , Doenças dos Cavalos/tratamento farmacológico , Cavalos , Humanos , Masculino , Rickettsia rickettsii , Febre Maculosa das Montanhas Rochosas/diagnóstico , Febre Maculosa das Montanhas Rochosas/tratamento farmacológico , Sudeste dos Estados Unidos
2.
J Vet Emerg Crit Care (San Antonio) ; 27(2): 198-205, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28207993

RESUMO

OBJECTIVE: To compare blood gas, electrolyte, and metabolic analysis results between blood obtained by jugular and transverse facial venous sinus (TFVS) venipuncture in healthy adult horses and sick adult horses presented for emergency evaluation. DESIGN: Prospective, experimental study, from June 2012 to October 2013. SETTING: Large animal university teaching hospital. ANIMALS: Ten healthy adult University-owned horses and 48 client-owned adult horses (≥2 years old) presenting to the large animal hospital emergency service for medical or surgical evaluation of systemic illness. INTERVENTIONS: Venipunctures (jugular vein [JV] and TFVS) were performed using preheparinized syringes and obtained prior to institution of medical therapy. Samples were analyzed in random order within a 10-minute interval using a point-of-care blood gas analyzer (NOVA Critical Care Xpress) that also reports electrolyte and metabolite results. Comparisons between venipuncture sites were analyzed using the Student's paired t-test for normally distributed data and the Wilcoxon paired test for nonnormally distributed data. Bland-Altman analysis was used to assess agreement between venipuncture sites. MEASUREMENTS AND MAIN RESULTS: There were no statistically significant differences found between variables for JV and TFVS in healthy horses. In sick horses, JV measurements were greater than TFVS for ionized calcium (P = 0.002) and glucose (P = 0.001), and less than TFVS for hematocrit (P = 0.015). Bland-Altman plots demonstrated small biases but overall agreement between sites. CONCLUSIONS: The TFVS can be used interchangeably with JV for venous blood gas analysis in healthy horses. In sick horses, identified differences were small and likely not clinically important. The reliability of this point-of-care blood gas analyzer for measurement of hematocrit remains to be determined.


Assuntos
Coleta de Amostras Sanguíneas/veterinária , Estado Terminal , Doenças dos Cavalos/sangue , Animais , Gasometria/veterinária , Estudos de Casos e Controles , Cuidados Críticos , Eletrólitos/sangue , Serviço Hospitalar de Emergência , Hematócrito/veterinária , Cavalos , Veias Jugulares , Sistemas Automatizados de Assistência Junto ao Leito , Estudos Prospectivos , Reprodutibilidade dos Testes
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