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BMC Surg ; 21(1): 138, 2021 Mar 17.
Artigo em Inglês | MEDLINE | ID: mdl-33731071

RESUMO

BACKGROUND: So called "mycotic" aortic aneurysms account for only 0.7 to 1.3% of all aortic aneurysms and are commonly caused by Staphylococcus aureus and Salmonella species. Bacillus Calmette-Guérin (BCG), a live attenuated strain of Mycobacterium bovis, is part of the therapy of non-muscle-invasive bladder cancer (NMIBC). CASE PRESENTATION: We report a case series of three patients with a mycobacterial graft infection related to BCG after surgical treatment of a presumed mycotic aortic aneurysm as an extremely rare complication after NMIBC treatment. All three patients developed aortic aneurysm after BCG instillation and subsequent mycobacterial graft infection. CONCLUSION: Diagnosis requires a high degree of suspicion because of its nonspecific symptoms and imaging. The pathogen is not detected by standard microbiological testing. Treatment includes triple antimycobacterial therapy and radical surgical interventions. Graft preservation may be considered if no anastomosis is involved.


Assuntos
Aneurisma Infectado/microbiologia , Aneurisma Aórtico/terapia , Vacina BCG/efeitos adversos , Imunoterapia/efeitos adversos , Infecções por Mycobacterium/complicações , Mycobacterium bovis/isolamento & purificação , Neoplasias da Bexiga Urinária/tratamento farmacológico , Administração Intravesical , Idoso , Antibacterianos/uso terapêutico , Vacina BCG/administração & dosagem , Humanos , Masculino , Pessoa de Meia-Idade , Infecções por Mycobacterium/tratamento farmacológico , Tomografia Computadorizada por Raios X , Resultado do Tratamento
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