Base-promoted perfluoroalkylation of rhodium(III) porphyrin complexes.

A new family of rhodium porphyrin complexes bearing a primary, secondary or benzylic perfluoroalkyl ligand RhIII(btpp)RF [btpp = 5,10,15,20-tetrakis(4-tert-butylphenyl)porphyrinato dianion] has been successfully synthesized in good yields using commercially available perfluoroalkyl iodides RFI (RF = nC3F7, iC3F7, nC4F9, nC6F13, cC6F11, nC10F21 and C6F5CF2) and the air-stable precursor RhIII(btpp)Cl under basic conditions. Mechanistic investigations suggest a halogen atom transfer pathway with a rhodium(ii) porphyrin metalloradical.

[Qianlie Jiedu capsule combined with rufloxacin for chronic prostatitis: a randomized double-blind controlled clinical trial].

OBJECTIVE: Few double-blind controlled trials have been reported on Chinese patent medicines for the treatment of chronic prostatitis. The purpose of this study was to investigate the therapeutic efficacy of Qianlie Jiedu Capsule for chronic prostatitis (CP) by the randomized double-blind controlled method. METHODS: Eighty CP patients were equally randomized into an experimental and a control group, the former treated with Qianlie Jiedu Capsule + Rufloxacin, and the latter given placebo + Rufloxacin, both for 4 weeks. All the patients were evaluated by NIH-CPSI and EPS examination before and after the medication. RESULTS: After 4-week treatment, the total score of NIH-CPSI and the scores of pain, voiding symptoms and quality of life were significantly decreased in both groups compared with the baseline (P < 0.05), so did the leukocyte count in EPS (P < 0.05). And the experimental group showed significant drops in the above scores as compared with the control (P < 0.05), except in the leukocyte count in EPS (P > 0.05). CONCLUSION: Qianlie Jiedu Capsule combined with Rufloxacin is highly effective for CP by relieving pain and voiding symptoms,decreasing the leukocyte count in EPS and improving the life quality of the patients.

[Successful treatment of high-flow priapism by selective arteriographic embolization of the pudendal artery].

OBJECTIVE: To evaluate the diagnosis and treatment of high-flow priapism (HFP). METHODS: Four cases of HFP following blunt trauma to the penis or perinea underwent diagnostic examination by colour-flow Doppler ultrasound and/or superselective pudendal arteriography, which revealed bilateral arteriocorporal fistula in 1 case and monolateral in the other 3. Penile detumescence was obtained in 2 cases by superselective bilateral/monolateral arteriographic embolization of the pudendal artery with absorbable gelatin RESULTS: The former 2 cases effected an immediate recovery of the sponge, while the other 2 cases received conservative treatment. Erectile function, able to perform normal sexual intercourse in approximately 2 months. But in the latter 2, follow-up revealed unsatisfactory potency. CONCLUSION: Superselective arteriographic embolization with absorbable gelatin sponge can provide a safe, selective and effective treatment for HFP patients.